Mouse LRIG1 Antibody | R&D Systems AF3688 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse LRIG1 Antibody

catalog :

AF3688

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation

more info or order :

R&D Systems product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; 1:2500; fig 6a	Hoesl C, Frohlich T, Posch C, Kneitz H, Goebeler M, Schneider M, et al. The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis. Mol Oncol. 2021;15:2140-2155 pubmed publisher
	Tu M, Liu R, Xue J, Xiao B, Li J, Liang L. Urban Particulate Matter Triggers Meibomian Gland Dysfunction. Invest Ophthalmol Vis Sci. 2024;65:8 pubmed publisher
	Lewis A, Kuwahara A, Franzosi J, Bush J. Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Rep. 2022;38:110510 pubmed publisher
	Xie Y, Kuan A, Wang W, Herbert Z, Mosto O, Olukoya O, et al. Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development. Cell Rep. 2022;38:110416 pubmed publisher
	Bieber J, Sanman L, Sun X, Hammerlindl H, Bao F, Roth M, et al. Differential toxicity to murine small and large intestinal epithelium induced by oncology drugs. Commun Biol. 2022;5:99 pubmed publisher
	Bhuju J, Olesen K, Muenyi C, Patel T, Read R, Thompson L, et al. Cutaneous Effects of In Utero and Lactational Exposure of C57BL/6J Mice to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxics. 2021;9: pubmed publisher
	Thulabandu V, Nehila T, Ferguson J, ATIT R. Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development. Dev Biol. 2021;478:25-40 pubmed publisher
	Huang S, Kuri P, Aubert Y, Brewster M, Li N, Farrelly O, et al. Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell. 2021;28:1582-1596.e6 pubmed publisher
	Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan D, et al. LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Rep. 2020;33:108257 pubmed publisher
	Kuwahara A, Lewis A, Coombes C, Leung F, Percharde M, Bush J. Delineating the early transcriptional specification of the mammalian trachea and esophagus. elife. 2020;9: pubmed publisher
	Piedrafita G, Kostiou V, Wabik A, Colom B, Fernández Antorán D, Herms A, et al. A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice. Nat Commun. 2020;11:1429 pubmed publisher
	Ge Y, Miao Y, Gur Cohen S, Gomez N, Yang H, Nikolova M, et al. The aging skin microenvironment dictates stem cell behavior. Proc Natl Acad Sci U S A. 2020;117:5339-5350 pubmed publisher
	Veniaminova N, Grachtchouk M, Doane O, Peterson J, Quigley D, Lull M, et al. Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin. Dev Cell. 2019;51:326-340.e4 pubmed publisher
	Oulès B, Rognoni E, Hoste E, Goss G, Fiehler R, Natsuga K, et al. Mutant Lef1 controls Gata6 in sebaceous gland development and cancer. EMBO J. 2019;38: pubmed publisher
	Napoletano F, Baron O, Vandenabeele P, Mollereau B, Fanto M. Intersections between Regulated Cell Death and Autophagy. Trends Cell Biol. 2019;29:323-338 pubmed publisher
	Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong S, et al. Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations. Cell Stem Cell. 2018;23:687-699.e8 pubmed publisher
	Singh K, Camera E, Krug L, Basu A, Pandey R, Munir S, et al. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin. Nat Commun. 2018;9:3425 pubmed publisher
	Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher
	Chovatiya G, Sarate R, Sunkara R, Gawas N, Kala V, Waghmare S. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response. Sci Rep. 2017;7:11619 pubmed publisher
	Hoeck J, Biehs B, Kurtova A, Kljavin N, De Sousa E Melo F, Alicke B, et al. Stem cell plasticity enables hair regeneration following Lgr5+ cell loss. Nat Cell Biol. 2017;19:666-676 pubmed publisher
	Ge Y, Gomez N, Adam R, Nikolova M, Yang H, Verma A, et al. Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell. 2017;169:636-650.e14 pubmed publisher

product information

master code :

AF3688

SKU :

AF3688

product name :

Mouse LRIG1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse LRIG1 Antibody from R&D Systems is a goat polyclonal antibody to LRIG1. This antibody reacts with mouse,transgenic mouse. The Mouse LRIG1 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry,Western Blot,CyTOF-ready.

target :

LRIG1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse LRIG1, Ala37-Thr794, Accession # P70193

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse LRIG1 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) LRIG1 is observed and less than 5% cross-reactivity with rhLRIG3 is observed.

gene symbol :

Lrig1

top caption :

Detection of Mouse LRIG1 antibody by Western Blot.

accessionNumbers :

P70193

applications :

Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry,Western Blot,CyTOF-ready

USD :

509 USD

alt names :

D6Bwg0781e, Img, LIG1, LIG-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage