product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CX3CL1/Fractalkine Chemokine Domain Antibody
catalog :
AF365
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 11
Reference
Wu C, Peng P, Renn T, Lee C, Chang T, Wei A, et al. CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells. J Cell Mol Med. 2023;27:1509-1522 pubmed publisher
Sun Y, Zhang X, Huang S, Pan H, Gai Y, Zhou Y, et al. Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis. J Immunol Res. 2022;2022:5665964 pubmed publisher
Coleman C, Stanley B, Lang C. Enrichment of Newly Synthesized Proteins following treatment of C2C12 Myotubes with Endotoxin and Interferon-γ. Inflammation. 2022;45:1313-1331 pubmed publisher
Que Z, Yao J, Zhou Z, Yu P, Luo B, Li H, et al. Jinfukang inhibits lung cancer metastasis by upregulating CX3CL1 to recruit NK cells to kill CTCs. J Ethnopharmacol. 2021;275:114175 pubmed publisher
Li J, Wuethrich A, Sina A, Cheng H, Wang Y, Behren A, et al. A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy. Nat Commun. 2021;12:1087 pubmed publisher
Panigrahi S, Chen B, Fang M, Potashnikova D, Komissarov A, Lebedeva A, et al. CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis. PLoS Pathog. 2020;16:e1008885 pubmed publisher
Ostuni M, Hermand P, Saindoy E, Guillou N, Guellec J, Coens A, et al. CX3CL1 homo-oligomerization drives cell-to-cell adherence. Sci Rep. 2020;10:9069 pubmed publisher
Avril M, Benjamin M, Dols M, Smith J. Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption. Sci Rep. 2019;9:13142 pubmed publisher
Nonn O, Güttler J, Forstner D, Maninger S, Zadora J, Balogh A, et al. Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction. Int J Mol Sci. 2019;20: pubmed publisher
Kim K, Kuang S, Song Q, Gavin T, Roseguini B. Impact of heat therapy on recovery after eccentric exercise in humans. J Appl Physiol (1985). 2019;126:965-976 pubmed publisher
Erreni M, Siddiqui I, Marelli G, Grizzi F, Bianchi P, Morone D, et al. The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination. J Immunol. 2016;196:902-14 pubmed publisher
product information
master code :
AF365
SKU :
AF365
product name :
Human CX3CL1/Fractalkine Chemokine Domain Antibody
unit size :
100 ug (also 25 ug)
description :
The Human CX3CL1/Fractalkine Chemokine Domain Antibody from R&D Systems is a goat polyclonal antibody to CX3CL1/Fractalkine. This antibody reacts with bovine,hamster,human,monkey. The Human CX3CL1/Fractalkine Chemokine Domain Antibody has been validated for the following applications: Western Blot,Bioassay,ELISA Development,Flow Cytometry,Neutralization,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
CX3CL1/Fractalkine
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human CX3CL1/Fractalkine, Gln25-Gly100, Accession # Q6I9S9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Bovine,Human
specificity :
Detects human CX3CL1/Fractalkine in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) MCP-2 and rhMCP-4 is observed.
gene symbol :
CX3CL1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CX3CL1/Fractalkine and Neutralization by Human CX3CL1/Fractalkine Antibody.
accessionNumbers :
Q6I9S9
applications :
Western Blot,Bioassay,ELISA Development,Flow Cytometry,Neutralization,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
489 USD
alt names :
ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.