Human Notch-1 Intracellular Domain Antibody | R&D Systems AF3647 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Notch-1 Intracellular Domain Antibody

catalog :

AF3647

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 4

Reference
Rajeh A, Cornman H, Gupta A, Szeto M, Kambala A, Oladipo O, et al. Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis. medRxiv. 2023;: pubmed publisher
Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed publisher
Hrstka S, Li X, Nelson T. NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis. Stem Cells. 2017;35:1106-1119 pubmed publisher
Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher

product information

master code :

AF3647

SKU :

AF3647

product name :

Human Notch-1 Intracellular Domain Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Notch-1 Intracellular Domain Antibody from R&D Systems is a sheep polyclonal antibody to Notch-1. This antibody reacts with human. The Human Notch-1 Intracellular Domain Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,Immunocytochemistry,Chromatin Immunoprecipitation (ChIP),CyTOF-ready.

target :

Notch-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

E. coli -derived recombinant human Notch-1, Gly2428-Lys2556, Accession # P46531

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects the intracellular domain (ICD) of human Notch-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Notch-2 ICD, rhNotch-3 ICD, and rhNotch-4 ICD is observed.

gene symbol :

NOTCH1

top caption :

Detection of Human Notch-1.

accessionNumbers :

P46531

applications :

Flow Cytometry,Western Blot,Immunohistochemistry,Immunocytochemistry,Chromatin Immunoprecipitation (ChIP),CyTOF-ready

USD :

489 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage