product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-33 Antibody
catalog :
AF3626
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 99
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 3h
Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al. A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Rep. 2021;35:108997 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 10f, 10p
Liu J, Wang C, Cheng T, Rixiati Y, Ji C, Deng M, et al. Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:251-276 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s2a
Chen W, Wu Y, Tsai T, Li R, Lai A, Li L, et al. Group 2 innate lymphoid cells contribute to IL-33-mediated alleviation of cardiac fibrosis. Theranostics. 2021;11:2594-2611 pubmed publisher
Wang M, Dufort C, Du Z, Shi R, Xu F, Huang Z, et al. IL-33/ST2 signaling in monocyte-derived macrophages maintains blood-brain barrier integrity and restricts infarctions early after ischemic stroke. J Neuroinflammation. 2024;21:274 pubmed publisher
Wei H, Zhen L, Wang S, Yang L, Zhang S, Zhang Y, et al. Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice. J Neuroinflammation. 2023;20:264 pubmed publisher
Hassan D, Chen J. CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair. bioRxiv. 2023;: pubmed publisher
Jiang Y, Donati V, Peters G, Giovannetti E, Deng D. Fungal mycobiome-mediated immune response: a non-negligible promoter in pancreatic oncogenesis and chemoresistance. Cancer Drug Resist. 2023;6:284-290 pubmed publisher
Du J, Liu Y, Lan G, Zhou Y, Ni Y, Liao K, et al. PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation. Cell Death Dis. 2023;14:432 pubmed publisher
Kaur G, Sharma D, Bisen S, Mukhopadhyay C, Gurdziel K, Singh N. Vascular cell-adhesion molecule 1 (VCAM-1) regulates JunB-mediated IL-8/CXCL1 expression and pathological neovascularization. Commun Biol. 2023;6:516 pubmed publisher
Ma Z, Li W, Zhuang L, Wen T, Wang P, Yu H, et al. TMEM59 ablation leads to loss of olfactory sensory neurons and impairs olfactory functions via interaction with inflammation. Brain Behav Immun. 2023;111:151-168 pubmed publisher
Liu M, Huang J, Liu T, Yuan J, Lv C, Sha Z, et al. Exogenous interleukin 33 enhances the brain's lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice. Acta Neuropathol Commun. 2023;11:61 pubmed publisher
Benvie A, Lee D, Steiner B, Xue S, Jiang Y, Berry D. Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice. Nat Commun. 2023;14:1806 pubmed publisher
Hou J, Zhou Y, Cai Z, Terekhova M, Swain A, Andhey P, et al. Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination. Cell Rep. 2023;42:112293 pubmed publisher
Zhou X, Hu Y, Liu L, Liu L, Chen H, Huang D, et al. IL-33-mediated activation of mast cells is involved in the progression of imiquimod-induced psoriasis-like dermatitis. Cell Commun Signal. 2023;21:52 pubmed publisher
Cheong L, Wang B, Wang Q, Jin L, Kwok K, Wu X, et al. Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice. Nat Commun. 2023;14:1213 pubmed publisher
Gurtner A, Borrelli C, Gonzalez Perez I, Bach K, Acar I, N xfa xf1 ez N, et al. Active eosinophils regulate host defence and immune responses in colitis. Nature. 2023;615:151-157 pubmed publisher
Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, et al. IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders. Int Immunopharmacol. 2023;114:109479 pubmed publisher
Widmayer P, Pregitzer P, Breer H. Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach. Histol Histopathol. 2023;38:273-286 pubmed publisher
Zhao J, Jung S, Li X, Li L, Kasinath V, Zhang H, et al. Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice. J Clin Invest. 2022;132: pubmed publisher
Vanherle L, Lidington D, Uhl F, Steiner S, Vassallo S, Skoug C, et al. Restoring myocardial infarction-induced long-term memory impairment by targeting the cystic fibrosis transmembrane regulator. EBioMedicine. 2022;86:104384 pubmed publisher
Yamakawa D, Tsuboi J, Kasahara K, Matsuda C, Nishimura Y, Kodama T, et al. Cilia-Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury. Adv Sci (Weinh). 2022;10:e2202632 pubmed publisher
Xu L, Wei C, Chen Y, Wu Y, Shou X, Chen W, et al. IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection. Nat Commun. 2022;13:6881 pubmed publisher
Dixit A, Sarver A, Zettervall J, Huang H, Zheng K, Brekken R, et al. Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling. JCI Insight. 2022;7: pubmed publisher
Jowett G, Read E, Roberts L, Coman D, Vil xe0 Gonz xe1 lez M, Zabinski T, et al. Organoids capture tissue-specific innate lymphoid cell development in mice and humans. Cell Rep. 2022;40:111281 pubmed publisher
El Naccache D, Chen F, Palma M, Lemenze A, Fischer M, Wu W, et al. Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells. Cell Rep. 2022;40:111150 pubmed publisher
Glaubitz J, Wilden A, Golchert J, Homuth G, V xf6 lker U, Br xf6 ker B, et al. In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response. Nat Commun. 2022;13:4502 pubmed publisher
Sharma D, Bisen S, Kaur G, Van Buren E, Rao G, Singh N. IL-33 enhances Jagged1 mediated NOTCH1 intracellular domain (NICD) deubiquitination and pathological angiogenesis in proliferative retinopathy. Commun Biol. 2022;5:479 pubmed publisher
Deng P, Wang L, Zhang Q, Chen S, Zhang Y, Xu H, et al. Therapeutic Potential of a Combination of Electroacupuncture and Human iPSC-Derived Small Extracellular Vesicles for Ischemic Stroke. Cells. 2022;11: pubmed publisher
Kos K, Aslam M, van de Ven R, Wellenstein M, Pieters W, van Weverwijk A, et al. Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche. Cell Rep. 2022;38:110447 pubmed publisher
Xie Y, Kuan A, Wang W, Herbert Z, Mosto O, Olukoya O, et al. Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development. Cell Rep. 2022;38:110416 pubmed publisher
Alam A, Levanduski E, Denz P, Villavicencio H, Bhatta M, Alhorebi L, et al. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell. 2022;40:153-167.e11 pubmed publisher
Meng X, Qian X, Ding X, Wang W, Yin X, Zhuang G, et al. Eosinophils regulate intra-adipose axonal plasticity. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
He D, Xu H, Zhang H, Tang R, Lan Y, Xing R, et al. Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function. Immunity. 2022;55:159-173.e9 pubmed publisher
Li X, Jiang B, Zou Y, Zhang J, Fu Y, Zhai X. Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid. Front Pharmacol. 2021;12:788977 pubmed publisher
Miller J, Lingegowda H, Symons L, Bougie O, Young S, Lessey B, et al. IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis. JCI Insight. 2021;6: pubmed publisher
Lu Y, Huang Y, Li J, Huang J, Zhang L, Feng J, et al. Eosinophil extracellular traps drive asthma progression through neuro-immune signals. Nat Cell Biol. 2021;23:1060-1072 pubmed publisher
Mikuls T, Gaurav R, Thiele G, England B, Wolfe M, Shaw B, et al. The impact of airborne endotoxin exposure on rheumatoid arthritis-related joint damage, autoantigen expression, autoimmunity, and lung disease. Int Immunopharmacol. 2021;100:108069 pubmed publisher
Clark J, Christian D, Gullicksrud J, Perry J, Park J, Jacquet M, et al. IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii. elife. 2021;10: pubmed publisher
Chetty A, Darby M, Vornewald P, Martín Alonso M, Filz A, Ritter M, et al. Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection. Cell Host Microbe. 2021;29:579-593.e5 pubmed publisher
Alonso Curbelo D, Ho Y, Burdziak C, Mååg J, Morris J, Chandwani R, et al. A gene-environment-induced epigenetic program initiates tumorigenesis. Nature. 2021;: pubmed publisher
Ferreira A, Szeto A, Heycock M, Clark P, Walker J, Crisp A, et al. RORα is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus. Nat Immunol. 2021;22:166-178 pubmed publisher
Botelho F, Dubey A, Ayaub E, Park R, Yip A, Humbles A, et al. IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M. Mediators Inflamm. 2020;2020:4087315 pubmed publisher
Leimkühler N, Gleitz H, Ronghui L, Snoeren I, Fuchs S, Nagai J, et al. Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell Stem Cell. 2020;: pubmed publisher
Perez F, Ruera C, Miculán E, Carasi P, Dubois Camacho K, Garbi L, et al. IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease. Front Immunol. 2020;11:581445 pubmed publisher
Still K, Batista S, O Brien C, Oyesola O, Früh S, Webb L, et al. Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling. PLoS Pathog. 2020;16:e1009027 pubmed publisher
Huang J, Gandini M, Chen L, M Dahoma S, Stemkowski P, Chung H, et al. Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk. Cell Rep. 2020;33:108233 pubmed publisher
Shani O, Vorobyov T, Monteran L, Lavie D, Cohen N, Raz Y, et al. Fibroblast-Derived IL33 Facilitates Breast Cancer Metastasis by Modifying the Immune Microenvironment and Driving Type 2 Immunity. Cancer Res. 2020;80:5317-5329 pubmed publisher
Chen L, Sun R, Xu J, Zhai W, Zhang D, Yang M, et al. Tumor-Derived IL33 Promotes Tissue-Resident CD8+ T Cells and Is Required for Checkpoint Blockade Tumor Immunotherapy. Cancer Immunol Res. 2020;8:1381-1392 pubmed publisher
Ljunggren Rose A, Natarajan C, Matta P, Pandey A, Upender I, Sriram S. Anacardic acid induces IL-33 and promotes remyelination in CNS. Proc Natl Acad Sci U S A. 2020;117:21527-21535 pubmed publisher
Aparicio Domingo P, Cannelle H, Buechler M, Nguyen S, Kallert S, Favre S, et al. Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection. Eur J Immunol. 2021;51:76-90 pubmed publisher
Chauch xe9 C, Vacca F, Chia S, Richards J, Gregory W, Ogunkanbi A, et al. A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine. Front Immunol. 2020;11:1363 pubmed publisher
Li T, Zhang Z, Bartolacci J, Dwyer G, Liu Q, Mathews L, et al. Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection. J Clin Invest. 2020;130:5397-5412 pubmed publisher
Wu K, Wang X, Keeler S, Gerovac B, Agapov E, Byers D, et al. Group 2 Innate Lymphoid Cells Must Partner with the Myeloid-Macrophage Lineage for Long-Term Postviral Lung Disease. J Immunol. 2020;205:1084-1101 pubmed publisher
Nguyen P, Dorman L, Pan S, Vainchtein I, Han R, Nakao Inoue H, et al. Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity. Cell. 2020;182:388-403.e15 pubmed publisher
Lamberet A, Rostan O, Dion S, Jan A, Guegan H, Manuel C, et al. IL-33/ST2 axis is involved in disease progression in the spleen during Leishmania donovani infection. Parasit Vectors. 2020;13:320 pubmed publisher
Farini A, Villa C, Di Silvestre D, Bella P, Tripodi L, Rossi R, et al. PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy. Front Physiol. 2020;11:403 pubmed publisher
Lee K, Bae J, Kim E, Kim J, Lyu L, Chung Y, et al. Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis. Clin Exp Otorhinolaryngol. 2020;: pubmed publisher
Takenaga K, Akimoto M, Koshikawa N, Nagase H. Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model. PLoS ONE. 2020;15:e0232230 pubmed publisher
Lu Y, Basatemur G, Scott I, Chiarugi D, Clement M, Harrison J, et al. Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages. Immunity. 2020;52:782-793.e5 pubmed publisher
Govatati S, Pichavaram P, Janjanam J, Guo L, Virmani R, Rao G. Myristoylation of LMCD1 Leads to Its Species-Specific Derepression of E2F1 and NFATc1 in the Modulation of CDC6 and IL-33 Expression During Development of Vascular Lesions. Arterioscler Thromb Vasc Biol. 2020;40:1256-1274 pubmed publisher
Flamar A, Klose C, Moeller J, Mahlakõiv T, Bessman N, Zhang W, et al. Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity. Immunity. 2020;52:606-619.e6 pubmed publisher
Begum S, Perlman B, Valero Pacheco N, O Besso V, Wu T, Morelli S, et al. Dynamic Expression of Interleukin-33 and ST2 in the Mouse Reproductive Tract Is Influenced by Superovulation. J Histochem Cytochem. 2020;68:253-267 pubmed publisher
Moral J, Leung J, Rojas L, Ruan J, Zhao J, Sethna Z, et al. ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity. Nature. 2020;579:130-135 pubmed publisher
Córdoba David G, Duro Castano A, Castelo Branco R, González Guerrero C, Cannata P, Sanz A, et al. Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate. Sci Rep. 2020;10:2056 pubmed publisher
Augustine J, Pavlou S, Ali I, Harkin K, Ozaki E, Campbell M, et al. IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment. J Neuroinflammation. 2019;16:251 pubmed publisher
Hussey G, Dziki J, Lee Y, Bartolacci J, Behun M, Turnquist H, et al. Matrix bound nanovesicle-associated IL-33 activates a pro-remodeling macrophage phenotype via a non-canonical, ST2-independent pathway. J Immunol Regen Med. 2019;3:26-35 pubmed publisher
Ximerakis M, Lipnick S, Innes B, Simmons S, Adiconis X, Dionne D, et al. Single-cell transcriptomic profiling of the aging mouse brain. Nat Neurosci. 2019;22:1696-1708 pubmed publisher
Drake L, Squillace D, Iijima K, Kobayashi T, Uchida M, Kephart G, et al. Early Life Represents a Vulnerable Time Window for IL-33-Induced Peripheral Lung Pathology. J Immunol. 2019;203:1952-1960 pubmed publisher
Huang H, Tsai S, Wu H, Huang H, Hsieh H, Kuo Y, et al. Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus. BMC Neurosci. 2019;20:33 pubmed publisher
Rana B, Jou E, Barlow J, Rodriguez Rodriguez N, Walker J, Knox C, et al. A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue. J Exp Med. 2019;: pubmed publisher
Eissmann M, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh A, et al. IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization. Nat Commun. 2019;10:2735 pubmed publisher
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, Canton T, Consiglio C, Albert M, et al. Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection. JCI Insight. 2019;5: pubmed publisher
Govatati S, Pichavaram P, Janjanam J, Zhang B, Singh N, Mani A, et al. NFATc1-E2F1-LMCD1-Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation. Arterioscler Thromb Vasc Biol. 2019;39:1212-1226 pubmed publisher
Weinberg E, Ferrán B, Tsukahara Y, Hatch M, Han J, Murdoch C, et al. IL-33 induction and signaling are controlled by glutaredoxin-1 in mouse macrophages. PLoS ONE. 2019;14:e0210827 pubmed publisher
Anderton H, Bandala Sanchez E, Simpson D, Rickard J, Ng A, Di Rago L, et al. RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. Cell Death Differ. 2019;26:877-889 pubmed publisher
Nabe T, Matsuda M, Ishida T, Tsujimoto N, Kido H, Kanaya H, et al. Antigen-specific airway IL-33 production depends on FcγR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice. Immunology. 2018;155:99-111 pubmed publisher
Dohi E, Choi E, Rose I, Murata A, Chow S, Niwa M, et al. Behavioral Changes in Mice Lacking Interleukin-33. Eneuro. 2017;4: pubmed publisher
Mahmutovic Persson I, Menzel M, Ramu S, Cerps S, Akbarshahi H, Uller L. IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation. Respir Res. 2018;19:16 pubmed publisher
Yamaguchi M, Samuchiwal S, Quehenberger O, Boyce J, Balestrieri B. Macrophages regulate lung ILC2 activation via Pla2g5-dependent mechanisms. Mucosal Immunol. 2018;11:615-626 pubmed publisher
Liu T, Barrett N, Kanaoka Y, Yoshimoto E, Garofalo D, Cirka H, et al. Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity. J Immunol. 2018;200:915-927 pubmed publisher
Chang J, Xia Y, Wasserloos K, Deng M, Blose K, Vorp D, et al. Cyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells. PLoS ONE. 2017;12:e0184770 pubmed publisher
Lv R, Zhao J, Lei M, Xiao D, Yu Y, Xie J. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell Physiol Biochem. 2017;42:1961-1972 pubmed publisher
Xu J, Guardado J, Hoffman R, Xu H, Namas R, Vodovotz Y, et al. IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model. PLoS Med. 2017;14:e1002365 pubmed publisher
Han M, Rajput C, Hong J, Lei J, Hinde J, Wu Q, et al. The Innate Cytokines IL-25, IL-33, and TSLP Cooperate in the Induction of Type 2 Innate Lymphoid Cell Expansion and Mucous Metaplasia in Rhinovirus-Infected Immature Mice. J Immunol. 2017;199:1308-1318 pubmed publisher
Lewis B, Sultana R, Sharma R, Noël A, Langohr I, Patial S, et al. Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease. J Immunol. 2017;199:1170-1183 pubmed publisher
Carrière V, Arshad M, Le Seyec J, Lefevre B, Farooq M, Jan A, et al. Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis. Mediators Inflamm. 2017;2017:1359064 pubmed publisher
Qi F, Bai S, Wang D, Xu L, Hu H, Zeng S, et al. Macrophages produce IL-33 by activating MAPK signaling pathway during RSV infection. Mol Immunol. 2017;87:284-292 pubmed publisher
Reverchon F, Mortaud S, Sivoyon M, Maillet I, Laugeray A, Palomo J, et al. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathog. 2017;13:e1006322 pubmed publisher
Nakagawa H, Suzuki N, Hirata Y, Hikiba Y, Hayakawa Y, Kinoshita H, et al. Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands. Proc Natl Acad Sci U S A. 2017;114:E3806-E3815 pubmed publisher
Sezaki T, Hirata Y, Hagiwara T, Kawamura Y, Okamura T, Takanashi R, et al. Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice. World J Gastroenterol. 2017;23:2294-2307 pubmed publisher
Chen S, Chen B, Wen Z, Huang Z, Ye L. IL-33/ST2-mediated inflammation in macrophages is directly abrogated by IL-10 during rheumatoid arthritis. Oncotarget. 2017;8:32407-32418 pubmed publisher
Li C, Maillet I, Mackowiak C, Viala C, Di Padova F, Li M, et al. Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells. Cell Death Dis. 2017;8:e2735 pubmed publisher
Oh J, Oh D, Jung H, Lee H. A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract. Proc Natl Acad Sci U S A. 2017;114:E1188-E1195 pubmed publisher
Lapérine O, Cloitre A, Caillon J, Huck O, Bugueno I, Pilet P, et al. Interleukin-33 and RANK-L Interplay in the Alveolar Bone Loss Associated to Periodontitis. PLoS ONE. 2016;11:e0168080 pubmed publisher
Lin S, Fu J, Wang C, Gao F, Feng X, Liu Q, et al. Inflammation elevated IL-33 originating from the lung mediates inflammation in acute lung injury. Clin Immunol. 2016;: pubmed publisher
Liu B, Tai Y, Achanta S, Kaelberer M, Caceres A, Shao X, et al. IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy. Proc Natl Acad Sci U S A. 2016;113:E7572-E7579 pubmed
Aguiniga L, Yaggie R, Schaeffer A, Klumpp D. Lipopolysaccharide Domains Modulate Urovirulence. Infect Immun. 2016;84:3131-3140 pubmed publisher
Athari S, Poirier E, Biton J, Semerano L, Hervé R, Raffaillac A, et al. Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33. Arthritis Res Ther. 2016;18:143 pubmed publisher
Mahmutovic Persson I, Akbarshahi H, Menzel M, Brandelius A, Uller L. Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation. J Transl Med. 2016;14:52 pubmed publisher
product information
brand :
R&D Systems
master code :
AF3626
SKU :
AF3626
product name :
Mouse IL-33 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse IL-33 Antibody from R&D Systems is a goat polyclonal antibody to IL-33. This antibody reacts with human,mouse,transgenic mouse. The Mouse IL-33 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunoprecipitation,Immunohistochemistry-Frozen,Neutralization,ELISA Development,ELISA Development (Capture),ELISpot Development,Flow Cytometry,Immunohistochemistry-Paraffin,In vivo assay,Immunofluorescence,Immunocytochemistry,ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
IL-33
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.4 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 10-50 ng/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 5-15 ug/mL, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse IL-33, Ser109-Ile266, Accession # Q8BVZ5
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse IL-33 in ELISAs and Western blots. In sandwich immunoassays, less than 2% cross-reactivity with recombinant human IL-33 is observed.
gene symbol :
IL33
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse IL-33 antibody by Western Blot.
accessionNumbers :
Q8BVZ5
applications :
ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready,ELISA Development,ELISA Development (Capture),ELISpot Development,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Neutralization,Immunofluorescence,Immunocytochemistry
USD :
489 USD
alt names :
C9orf26, C9orf26chromosome 9 open reading frame 26 (NF-HEV), DKFZp586H0523, DVS27, DVS27-related protein, IL1F11, IL-1F11, IL33, IL-33, interleukin 33, Interleukin-1 family member 11, interleukin-33, NFHEV, NF-HEV, NF-HEVNFEHEV, Nuclear factor from high endothelial venules, RP11-575C20.2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.