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company name :
R&D Systems
product type :
antibody
product name :
Human CCL20/MIP-3 alpha Antibody
catalog :
AF360
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Parween F, Singh S, Zhang H, Kathuria N, Otaizo Carrasquero F, Shamsaddini A, et al. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells. bioRxiv. 2023;: pubmed publisher
Brink K, Hunt M, Mu A, Groszman K, Hoang K, Lorch K, et al. An E. coli display method for characterization of peptide-sensor kinase interactions. Nat Chem Biol. 2022;: pubmed publisher
Wang W, Lin Y, Zhang F, Lei W, Pan F, Zhu Y, et al. Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition. Cell Biosci. 2022;12:64 pubmed publisher
Kwantwi L, Wang S, Zhang W, Peng W, Cai Z, Sheng Y, et al. Tumor-associated neutrophils activated by tumor-derived CCL20 (C-C motif chemokine ligand 20) promote T cell immunosuppression via programmed death-ligand 1 (PD-L1) in breast cancer. Bioengineered. 2021;12:6996-7006 pubmed publisher
Booth J, Duggan E, Patel V, Wu W, Burian D, Hutchings D, et al. Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines. Microb Pathog. 2018;121:9-21 pubmed publisher
Zhang X, Hu Z, Meng A, Duan G, Zhao Q, Yang J. Role of CCL20/CCR6 and the ERK signaling pathway in lung adenocarcinoma. Oncol Lett. 2017;14:8183-8189 pubmed publisher
Rump L, Mattey D, Kehoe O, Middleton J. An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine. 2017;97:133-140 pubmed publisher
Ye X, Wang R, Bhattacharya R, Boulbés D, Fan F, Xia L, et al. Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors. Cancer Prev Res (Phila). 2017;10:398-409 pubmed publisher
product information
master code :
AF360
SKU :
AF360
product name :
Human CCL20/MIP-3 alpha Antibody
unit size :
100 ug (also 25 ug)
description :
The Human CCL20/MIP-3 alpha Antibody from R&D Systems is a goat polyclonal antibody to CCL20/MIP-3 alpha. This antibody reacts with human,mouse. The Human CCL20/MIP-3 alpha Antibody has been validated for the following applications: Immunohistochemistry,Neutralization,Bioassay,ELISA Development,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
CCL20/MIP-3 alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human CCL20/MIP-3 alpha , Ala27-Met96 (Asn95Asp), Accession # P78556
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human CCL20/MIP-3 alpha in direct ELISAs.
gene symbol :
CCL20
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
CCL20/MIP-3a antibody in Human PBMCs by Immunocytochemistry (ICC).
accessionNumbers :
P78556
applications :
Neutralization,Bioassay,ELISA Development,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
beta chemokine exodus-1, Beta-chemokine exodus-1, CC chemokine LARC, C-C motif chemokine 20, chemokine (C-C motif) ligand 20, CKb4, exodus-1, LARC, LARCLiver and activation-regulated chemokine, MIP3 alpha, MIP-3 alpha, MIP-3a, MIP-3-alpha, MIP3AMacrophage inflammatory protein 3 alpha, SCYA20Small-inducible cytokine A20, small inducible cytokine subfamily A (Cys-Cys), member 20, ST38
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.