product summary
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company name :
R&D Systems
product type :
antibody
product name :
Tau Antibody
catalog :
AF3494
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Meduri G, Guillemeau K, Daguinot C, Dounane O, Genet M, Ferrara L, et al. Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies. J Alzheimers Dis. 2023;94:313-331 pubmed publisher
Bathini P, Dupanloup I, Zenaro E, Terrabuio E, Fischer A, Ballabani E, et al. Systemic Inflammation Causes Microglial Dysfunction With a Vascular AD phenotype. Brain Behav Immun Health. 2023;28:100568 pubmed publisher
Largo Barrientos P, Apóstolo N, Creemers E, Callaerts Vegh Z, Swerts J, Davies C, et al. Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation. Neuron. 2021;109:767-777.e5 pubmed publisher
Pickett E, Herrmann A, McQueen J, Abt K, Dando O, Tulloch J, et al. Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease. Cell Rep. 2019;29:3592-3604.e5 pubmed publisher
Bathini P, Mottas A, Jaquet M, Brai E, Alberi L. Progressive signaling changes in the olfactory nerve of patients with Alzheimer's disease. Neurobiol Aging. 2019;76:80-95 pubmed publisher
product information
master code :
AF3494
SKU :
AF3494
product name :
Tau Antibody
unit size :
100 ug (also 25 ug)
description :
The Tau Antibody from R&D Systems is a goat polyclonal antibody to Tau. This antibody reacts with human,multi-species. The Tau Antibody has been validated for the following applications: Immunohistochemistry,Western Blot.
target :
Tau
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human Tau, Gln624-Gln756, Accession # P10636
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Multi-Species
specificity :
Detects human Tau in direct ELISAs and Western blots.
gene symbol :
MAPT
top caption :
Tau antibody in Human Alzheimer's Disease Brain by Immunohistochemistry (IHC-P).
accessionNumbers :
P10636
applications :
Immunohistochemistry,Western Blot
USD :
479 USD
alt names :
DDPAC, FLJ31424, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, MAPT, MGC138549, microtubule-associated protein tau, MSTD, MSTDMAPTL, MTBT1, MTBT1Neurofibrillary tangle protein, MTBT2, Neurofibrillary tangle protein, PHF-tau, PPND, tau, TAUPaired helical filament-tau
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.