Human VEGFR3/Flt-4 Antibody | R&D Systems AF349 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGFR3/Flt-4 Antibody

catalog :

AF349

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4a	Lee S, Rho S, Park H, Park J, Kim J, Lee I, et al. Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. J Clin Invest. 2017;127:457-471 pubmed publisher
	Creff J, Lamaa A, Benuzzi E, Balzan E, Pujol F, Draia Nicolau T, et al. Apelin-VEGF-C mRNA delivery as therapeutic for the treatment of secondary lymphedema. EMBO Mol Med. 2024;16:386-415 pubmed publisher
	Garg R, Endzhievskaya S, Williamson M. B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancer. Cancer Gene Ther. 2023;30:1513-1523 pubmed publisher
	Jannaway M, Iyer D, Mastrogiacomo D, Li K, Sung D, Yang Y, et al. VEGFR3 is required for button junction formation in lymphatic vessels. Cell Rep. 2023;42:112777 pubmed publisher
	Das A, Ash D, Fouda A, Sudhahar V, Kim Y, Hou Y, et al. Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis. Nat Cell Biol. 2022;24:35-50 pubmed publisher
	Park M, Kim J, Kim T, Kim S, Park W, Ha K, et al. REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expression. Exp Mol Med. 2021;53:1612-1622 pubmed publisher
	Thomson B, Liu P, Onay T, Du J, Tompson S, Misener S, et al. Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies. Nat Commun. 2021;12:6072 pubmed publisher
	Bernatz S, Monden D, Gessler F, Radic T, Hattingen E, Senft C, et al. Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients. J Mol Histol. 2021;52:233-243 pubmed publisher
	Ella Tongwiis P, Lamb R, Makanga A, Shergill I, Hughes S. The role of antibody expression and their association with bladder cancer recurrence: a single-centre prospective clinical-pilot study in 35 patients. BMC Urol. 2020;20:187 pubmed publisher
	Wei S, Huang Y, Hsieh M, Lin Y, Shyu W, Chen H, et al. Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Cell Death Dis. 2020;11:307 pubmed publisher
	Urner S, Planas Paz L, Hilger L, Henning C, Branopolski A, Kelly Goss M, et al. Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth. EMBO J. 2019;38: pubmed publisher
	Volk Draper L, Hall K, Wilber A, Ran S. Lymphatic endothelial progenitors originate from plastic myeloid cells activated by toll-like receptor-4. PLoS ONE. 2017;12:e0179257 pubmed publisher
	Heinolainen K, Karaman S, D Amico G, Tammela T, Sormunen R, Eklund L, et al. VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling. Circ Res. 2017;120:1414-1425 pubmed publisher
	Parry T, Ganguly A, Troy E, Luis Guerrero J, Iaci J, Srinivas M, et al. Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction. Eur J Pharmacol. 2017;796:76-89 pubmed publisher
	Takamura S, Yagi H, Hakata Y, Motozono C, McMaster S, Masumoto T, et al. Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance. J Exp Med. 2016;213:3057-3073 pubmed
	Scherer S, Bauer J, Schmaus A, Neumaier C, Herskind C, Veldwijk M, et al. TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT). PLoS ONE. 2016;11:e0162221 pubmed publisher
	Wakisaka N, Hasegawa Y, Yoshimoto S, Miura K, Shiotani A, Yokoyama J, et al. Primary Tumor-Secreted Lymphangiogenic Factors Induce Pre-Metastatic Lymphvascular Niche Formation at Sentinel Lymph Nodes in Oral Squamous Cell Carcinoma. PLoS ONE. 2015;10:e0144056 pubmed publisher

product information

master code :

AF349

SKU :

AF349

product name :

Human VEGFR3/Flt-4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human VEGFR3/Flt-4 Antibody from R&D Systems is a goat polyclonal antibody to VEGFR3/Flt-4. This antibody reacts with human,mouse,transgenic mouse. The Human VEGFR3/Flt-4 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Western Blot,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

VEGFR3/Flt-4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human VEGFR3/Flt-4, Tyr25-Ile776, Accession # P35916

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects human VEGFR3/Flt-4 in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant mouse VEGFR3 is observed and less than 2% cross-reactivity with recombinant human VEGFR1 is observed.

gene symbol :

FLT4

top caption :

VEGFR3/Flt-4 antibody in Human Cervical Squamous Metaplasia by Immunohistochemistry (IHC-P).

accessionNumbers :

P35916

applications :

Immunohistochemistry,Immunocytochemistry,Western Blot,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

489 USD

alt names :

EC 2.7.10, EC 2.7.10.1, Flt-4, FLT4, fms-related tyrosine kinase 4, LMPH1A, PCLFLT41, soluble VEGFR3 variant 1, soluble VEGFR3 variant 2, soluble VEGFR3 variant 3, Tyrosine-protein kinase receptor FLT4, vascular endothelial growth factor receptor 3, VEGF R3, VEGFR-3, VEGFR3Fms-like tyrosine kinase 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage