Human Wnt-7b Antibody | R&D Systems AF3460 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Wnt-7b Antibody

catalog :

AF3460

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Martín Flores N, Podpolny M, McLeod F, Workman I, Crawford K, Ivanov D, et al. Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model. elife. 2024;12: pubmed publisher
Militi S, Nibhani R, Jalali M, Pauklin S. RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling. Cell Rep. 2023;42:113146 pubmed publisher
Zhang Z, Xu Y, Zhao C. Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer. Cancer Med. 2021;10:3332-3345 pubmed publisher
Jiang S, Li Q, Liu Y, Zhang H, Wang Q, Chen Y, et al. Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis. BMC Cancer. 2021;21:180 pubmed publisher
Wang Z, Yin P, Sun Y, Na L, Gao J, Wang W, et al. LGR4 maintains HGSOC cell epithelial phenotype and stem-like traits. Gynecol Oncol. 2020;159:839-849 pubmed publisher
Beeler J, Marshall C, Gonzalez Ericsson P, Shaver T, Santos Guasch G, Lea S, et al. p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS ONE. 2019;14:e0218458 pubmed publisher
Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, et al. JUNB governs a feed-forward network of TGF? signaling that aggravates breast cancer invasion. Nucleic Acids Res. 2017;: pubmed publisher
Vesel M, Rapp J, Feller D, Kiss E, Jaromi L, Meggyes M, et al. ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling. Respir Res. 2017;18:52 pubmed publisher
Rider V, Talbott A, Bhusri A, Krumsick Z, Foster S, Wormington J, et al. WINGLESS (WNT) signaling is a progesterone target for rat uterine stromal cell proliferation. J Endocrinol. 2016;229:197-207 pubmed publisher
Newman D, Sills W, Hanrahan K, Ziegler A, Tidd K, Cook E, et al. Expression of WNT5A in Idiopathic Pulmonary Fibrosis and Its Control by TGF-Î² and WNT7B in Human Lung Fibroblasts. J Histochem Cytochem. 2016;64:99-111 pubmed publisher

product information

master code :

AF3460

SKU :

AF3460

product name :

Human Wnt-7b Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Wnt-7b Antibody from R&D Systems is a goat polyclonal antibody to Wnt-7b. This antibody reacts with human,mouse,rat. The Human Wnt-7b Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

Wnt-7b

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human Wnt-7b, Leu32-Glu72 & Thr216-Ala283, Accession # P56706

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human Wnt-7b in direct ELISAs and Western blots. In Western blots, approximately 20% cross-reactivity with recombinant human (rh) Wnt-7a is observed and less than 5% cross-reactivity with recombinant mouse (rm) Wnt-1, rmWnt-3a, rmWnt-4, rmWnt-5a, rhWnt-9a, rmWnt-11, and rmWnt-16 is observed.

gene symbol :

WNT7B

top caption :

Detection of Human Wnt-7b antibody by Western Blot.

accessionNumbers :

P56706

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

469 USD

alt names :

protein Wnt-7b, wingless-type MMTV integration site family, member 7B, Wnt7b

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage