product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse GLI-1 Antibody
catalog :
AF3455
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 11
Reference
Jeffery E, Mann T, Pool J, Zhao Z, Morrison S. Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair. Cell Stem Cell. 2022;29:1547-1561.e6 pubmed publisher
Lei X, Li Z, Zhong Y, Li S, Chen J, Ke Y, et al. Gli1 promotes epithelial-mesenchymal transition and metastasis of non-small cell lung carcinoma by regulating snail transcriptional activity and stability. Acta Pharm Sin B. 2022;12:3877-3890 pubmed publisher
Sobecki M, Chen J, Krzywinska E, Nagarajan S, Fan Z, Nelius E, et al. Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell. 2022;29:1459-1474.e9 pubmed publisher
Min M, Song T, Sun M, Wang T, Tan J, Zhang J. Dhh signaling pathway regulates reconstruction of seminiferous tubule-like structure. Reprod Biol. 2022;22:100684 pubmed publisher
Po A, Citarella A, Catanzaro G, Besharat Z, Trocchianesi S, Gianno F, et al. Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells. Sci Rep. 2020;10:13988 pubmed publisher
Lei X, Zhong Y, Huang L, Li S, Fu J, Zhang L, et al. Identification of a novel tumor angiogenesis inhibitor targeting Shh/Gli1 signaling pathway in Non-small cell lung cancer. Cell Death Dis. 2020;11:232 pubmed publisher
Belgacemi R, Luczka E, Ancel J, Diabasana Z, Perotin J, Germain A, et al. Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD. EBioMedicine. 2020;51:102572 pubmed publisher
Aravani D, Morris G, Jones P, Tattersall H, Karamanavi E, Kaiser M, et al. HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis. Circulation. 2019;140:500-513 pubmed publisher
Mirza A, McKellar S, Urman N, Brown A, Hollmig T, Aasi S, et al. LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Cell. 2019;176:198-212.e15 pubmed publisher
Coutu D, Kokkaliaris K, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018;15:39-46 pubmed publisher
Tukachinsky H, Petrov K, Watanabe M, Salic A. Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog. Proc Natl Acad Sci U S A. 2016;113:E5866-E5875 pubmed
product information
master code :
AF3455
SKU :
AF3455
product name :
Human/Mouse GLI-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse GLI-1 Antibody from R&D Systems is a goat polyclonal antibody to GLI-1. This antibody reacts with human,mouse. The Human/Mouse GLI-1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
GLI-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse GLI-1, Met1-Glu237, Accession # P47806
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human and mouse GLI-1.
gene symbol :
GLI1
top caption :
Detection of Human GLI-1 antibody by Western Blot.
accessionNumbers :
P47806
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
489 USD
alt names :
GLI family zinc finger 1, GLI1, Glioma-associated oncogene, glioma-associated oncogene family zinc finger 1, glioma-associated oncogene homolog 1 (zinc finger protein), GLIzinc finger protein GLI1, Oncogene GLI
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.