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company name :
R&D Systems
product type :
antibody
product name :
Mouse ACE-2 Antibody
catalog :
AF3437
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 17
Reference
McCauley H, Riedman A, Enriquez J, Zhang X, Watanabe Chailland M, Sanchez J, et al. Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to Nutrients. Cell Mol Gastroenterol Hepatol. 2023;15:1293-1310 pubmed publisher
Enriquez J, McCauley H, Zhang K, Sanchez J, Kalin G, Lang R, et al. A dietary change to a high-fat diet initiates a rapid adaptation of the intestine. Cell Rep. 2022;41:111641 pubmed publisher
Brown J, Sanidad K, Lucotti S, Lieber C, Cox R, Ananthanarayanan A, et al. Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. Gut Microbes. 2022;14:2105609 pubmed publisher
Khaddaj Mallat R, Aldib N, Bernard M, Paquette A, Ferreira A, Lecordier S, et al. SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein. Neurobiol Dis. 2021;161:105561 pubmed publisher
Kamle S, Ma B, He C, Akosman B, Zhou Y, Lee C, et al. Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19. JCI Insight. 2021;6: pubmed publisher
Bilinska K, von Bartheld C, Butowt R. Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19. Front Cell Neurosci. 2021;15:674123 pubmed publisher
Falach R, Bar On L, Lazar S, Kadar T, Mazor O, Aftalion M, et al. Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2. JCI Insight. 2021;6: pubmed publisher
Dani N, Herbst R, McCabe C, Green G, Kaiser K, Head J, et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021;184:3056-3074.e21 pubmed publisher
Naidu V, Zeki A, Sharma P. Sex differences in the induction of angiotensin converting enzyme 2 (ACE-2) in mouse lungs after e-cigarette vapor exposure and its relevance to COVID-19. J Investig Med. 2021;69:954-961 pubmed publisher
Bilinska K, von Bartheld C, Butowt R. Expression of the ACE2 virus entry protein in the nervus terminalis reveals the potential for an alternative route to brain infection in COVID-19. bioRxiv. 2021;: pubmed publisher
Miličić Stanić B, Maddox S, de Souza A, Wu X, Mehranfard D, Ji H, et al. Male bias in ACE2 basic science research: missed opportunity for discovery in the time of COVID-19. Am J Physiol Regul Integr Comp Physiol. 2021;320:R925-R937 pubmed publisher
Lallai V, Manca L, Fowler C. E-cigarette vape and lung ACE2 expression: Implications for coronavirus vulnerability. Environ Toxicol Pharmacol. 2021;86:103656 pubmed publisher
Wohlrab P, Johann Danhofer M, Schaubmayr W, Tiboldi A, Krenn K, Markstaller K, et al. Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions. Physiol Rep. 2021;9:e14590 pubmed publisher
Kamle S, Ma B, He C, Akosman B, Zhou Y, Lee C, et al. Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19. bioRxiv. 2021;: pubmed publisher
Bilinska K, Jakubowska P, von Bartheld C, Butowt R. Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. ACS Chem Neurosci. 2020;11:1555-1562 pubmed publisher
Wysocki J, Schulze A, Batlle D. Novel Variants of Angiotensin Converting Enzyme-2 of Shorter Molecular Size to Target the Kidney Renin Angiotensin System. Biomolecules. 2019;9: pubmed publisher
Jando J, Camargo S, Herzog B, Verrey F. Expression and regulation of the neutral amino acid transporter B0AT1 in rat small intestine. PLoS ONE. 2017;12:e0184845 pubmed publisher
product information
master code :
AF3437
SKU :
AF3437
product name :
Mouse ACE-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse ACE-2 Antibody from R&D Systems is a goat polyclonal antibody to ACE-2. This antibody reacts with mouse,rat,transgenic mouse. The Mouse ACE-2 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Flow Cytometry,ELISA,Immunoprecipitation,Simple Western.
target :
ACE-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant mouse ACE-2, Gln18-Thr740, Accession # Q8R0I0
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse ACE-2 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant rat ACE-2 and 10% cross-reactivity with recombinant human ACE-2 is observed.
gene symbol :
ACE2
top caption :
Detection of Mouse ACE-2 antibody by Western Blot.
accessionNumbers :
Q8R0I0
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Flow Cytometry,ELISA,Immunoprecipitation,Simple Western
USD :
499 USD
alt names :
ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.