Human/Mouse/Rat Activin A ▀A subunit Antibody | R&D Systems AF338 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Activin A ▀A subunit Antibody

catalog :

AF338

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 15

Reference
Muhamad S, Safuan S, Stanslas J, Wan Ahmad W, Bushra S, Nurul A. Lignosus rhinocerotis extract ameliorates airway inflammation and remodelling via attenuation of TGF-β1 and Activin A in a prolonged induced allergic asthma model. Sci Rep. 2023;13:18442 pubmed publisher
Whiley P, Luu M, O Donnell L, Handelsman D, Loveland K. Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure. Front Endocrinol (Lausanne). 2023;14:1234712 pubmed publisher
Xu J, Zhang L, Li M, He X, Luo J, Wu R, et al. TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair. J Neuroinflammation. 2023;20:50 pubmed publisher
Sugii H, Albougha M, Adachi O, Tomita H, Tomokiyo A, Hamano S, et al. Activin A Promotes Osteoblastic Differentiation of Human Preosteoblasts through the ALK1-Smad1/5/9 Pathway. Int J Mol Sci. 2021;22: pubmed publisher
Mundy C, Yao L, Sinha S, Chung J, Rux D, Catheline S, et al. Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice. Sci Signal. 2021;14: pubmed publisher
Werner C, Mitra S, Auerbach B, Wang Z, Martin J, Stewart A, et al. Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence. Proc Natl Acad Sci U S A. 2020;117:26460-26469 pubmed publisher
Thomas A, Castellanos K, Mancinelli G, Xia Y, Bauer J, Yazici C, et al. Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index. Clin Transl Gastroenterol. 2020;11:e00152 pubmed publisher
Lepletier A, Hun M, Hammett M, Wong K, Naeem H, Hedger M, et al. Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging. Cell Rep. 2019;27:3887-3901.e4 pubmed publisher
Jin Q, Qiao C, Li J, Xiao B, Li J, Xiao X. A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice. Skelet Muscle. 2019;9:16 pubmed publisher
Lemaitre R, Bogdanova A, Borgonovo B, Woodruff J, Drechsel D. FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing. BMC Biotechnol. 2019;19:20 pubmed publisher
Carlton A, Illendula A, Gao Y, Llaneza D, Boulton A, Shah A, et al. Small molecule inhibition of the CBFβ/RUNX interaction decreases ovarian cancer growth and migration through alterations in genes related to epithelial-to-mesenchymal transition. Gynecol Oncol. 2018;149:350-360 pubmed publisher
Hu J, Wang X, Tang Y, Shan Y, Zou Q, Wang Z, et al. Activin A inhibition attenuates sympathetic neural remodeling following myocardial infarction in rats. Mol Med Rep. 2018;17:5074-5080 pubmed publisher
Staudacher J, Yazici C, Carroll T, Bauer J, Pang J, Krett N, et al. Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target. Sci Rep. 2017;7:12786 pubmed publisher
Wallner C, Jaurich H, Wagner J, Becerikli M, Harati K, Dadras M, et al. Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2. Sci Rep. 2017;7:9878 pubmed publisher
Merfeld Clauss S, Lu H, Wu X, March K, Traktuev D. Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity. J Cell Mol Med. 2018;22:173-184 pubmed publisher

product information

brand :

R&D Systems

master code :

AF338

SKU :

AF338

product name :

Human/Mouse/Rat Activin A ▀A subunit Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat Activin A ßA subunit Antibody from R&D Systems is a goat polyclonal antibody to Activin A. This antibody reacts with canine,human,mouse,porcine,primate - chlorocebus pygerythrus (vervet monkey),rat. The Human/Mouse/Rat Activin A ßA subunit Antibody has been validated for the following applications: Immunohistochemistry,Neutralization,ELISA Development,Flow Cytometry,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.

target :

Activin A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 2-6 ug/mL, Immunocytochemistry 5-25 ug/mL

host :

Goat

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Activin A

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Canine,Human,Mouse,Porcine,Primate - Chlorocebus pygerythrus (Vervet Monkey),Rat

specificity :

Detects human, mouse and rat Activin A in direct ELISAs and Western blots.

gene symbol :

INHBA

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Activin A antibody in SK-BR-3 and HeLa Human Cell Lines by Immunocytochemistry (ICC).

applications :

ELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Neutralization,Immunocytochemistry,Functional Assay

USD :

489 USD

alt names :

activin AB alpha polypeptide, Activin beta-A chain, erythroid differentiation factor, Erythroid differentiation protein, follicle-stimulating hormone-releasing protein, FSH-releasing protein, inhibin beta A chain, inhibin beta A subunit, Inhibin, beta-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage