product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat SOX1 Antibody
catalog :
AF3369
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 114
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:50; fig s5
Rhinn M, Zapata Bodalo I, Klein A, Plassat J, Knauer Meyer T, Keyes W. Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects. PLoS Biol. 2022;20:e3001664 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200-1:2000; loading ...; fig s1e
  • immunohistochemistry - frozen section; human; 1:200-1:2000; fig 5c
  • immunohistochemistry - frozen section; African green monkey; 1:200-1:2000; loading ...; fig 3c
Zhu X, Guo Y, Chu C, Liu D, Duan K, Yin Y, et al. BRN2 as a key gene drives the early primate telencephalon development. Sci Adv. 2022;8:eabl7263 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig s1e
Yoo J, Lee D, Park S, Shin H, Lee K, Kim D, et al. Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells. NPJ Parkinsons Dis. 2021;7:61 pubmed publisher
  • immunocytochemistry; human; fig 2b
Salas A, Duarri A, Fontrodona L, Ram xed rez D, Badia A, Isla Magran xe9 H, et al. Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration. Mol Ther Methods Clin Dev. 2021;20:688-702 pubmed publisher
  • immunocytochemistry; human; 1:150; loading ...; fig 1b
Jansch C, Ziegler G, Forero A, Gredy S, W xe4 ldchen S, Vitale M, et al. Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. J Neural Transm (Vienna). 2021;128:225-241 pubmed publisher
Huang C, Qiu L, Zhou W, Shao C, Wang X, Zhang Q, et al. A human-induced pluripotent stem cell (iPSC) line (SMUSHi006-A) from an ALS patient carrying a mutation c.1126C > T in the FUS gene. Stem Cell Res. 2025;82:103604 pubmed publisher
McCreery K, Stubb A, Stephens R, Fursova N, Cook A, Kruse K, et al. Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells. bioRxiv. 2024;: pubmed publisher
Zhao M, Wang J, Liu M, Xu Y, Huang J, Zhang Y, et al. KIF1A, R1457Q, and P1688L Mutations Induce Protein Abnormal Aggregation and Autophagy Impairment in iPSC-Derived Motor Neurons. Biomedicines. 2024;12: pubmed publisher
Tonin R, Feo F, Falliano S, Giunti L, Calamai M, Procopio E, et al. Generation of a human induced pluripotent stem cell line from a patient with GM3 synthase deficiency using self-replicating RNA vector. Stem Cell Res. 2024;77:103431 pubmed publisher
Kanemura Y, Yamamoto A, Katsuma A, Fukusumi H, Shofuda T, Kanematsu D, et al. Human-Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Showed Neuronal Differentiation, Neurite Extension, and Formation of Synaptic Structures in Rodent Ischemic Stroke Brains. Cells. 2024;13: pubmed publisher
Sun Z, Chen Z, Yin M, Wu X, Guo B, Cheng X, et al. Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids. Cell Stem Cell. 2024;31:772-787.e11 pubmed publisher
Werren E, LaForce G, Srivastava A, Perillo D, Li S, Johnson K, et al. TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome. Nat Commun. 2024;15:1640 pubmed publisher
Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, et al. Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids. Sci Rep. 2024;14:3936 pubmed publisher
Liu C, Xie Y, Chen X, Liu L, Liu C, Yin Z. BAF45D-binding to HOX genes was differentially targeted in H9-derived spinal cord neural stem cells. Sci Rep. 2024;14:29 pubmed publisher
Tang M, Xiong M, Zhou W, Lei J, Huang M, Huang C, et al. Generation of a human induced pluripotent stem cell line (SMUSHi002-A) from an ALS patient carrying a heterozygous mutation c.1562G > A in the FUS gene. Stem Cell Res. 2024;74:103286 pubmed publisher
Park S, Park C, Eom J, Jo M, Hur H, Choi S, et al. Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson's disease. Cell Stem Cell. 2024;31:25-38.e8 pubmed publisher
Tao Y, Li X, Dong Q, Kong L, Petersen A, Yan Y, et al. Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells. Nat Biotechnol. 2023;: pubmed publisher
Jaratsittisin J, Sornjai W, Chailangkarn T, Jongkaewwattana A, Smith D. The vitamin D receptor agonist EB1089 can exert its antiviral activity independently of the vitamin D receptor. PLoS ONE. 2023;18:e0293010 pubmed publisher
Oleksy C, Massart F, Goldwurm S, Arado A, Arena G, Boussaad I, et al. Generation and characterization of induced pluripotent stem cells from a Parkinson's disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations. Stem Cell Res. 2023;72:103212 pubmed publisher
Fiock K, Hook J, Hefti M. Determinants of astrocytic pathology in stem cell models of primary tauopathies. Acta Neuropathol Commun. 2023;11:161 pubmed publisher
Stanberry I, Cunningham D, Ye S, Alonzo M, Zhao M, Garg V, et al. Characterization of an induced pluripotent stem cell line NCHi011-A from a 23-year-old female with Alagille Syndrome harboring a heterozygous JAG1 pathogenic variant. Stem Cell Res. 2023;72:103213 pubmed publisher
Ong A, Kokaji T, Kishi A, Takihara Y, Shinozuka T, Shimamoto R, et al. Acquisition of neural fate by combination of BMP blockade and chromatin modification. iScience. 2023;26:107887 pubmed publisher
Wenker S, Farias M, Gradaschi V, Garcia C, Beauquis J, Leal M, et al. Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. PLoS ONE. 2023;18:e0263021 pubmed publisher
Mulica P, Venegas C, Landoulsi Z, Badanjak K, Delcambre S, Tziortziou M, et al. Comparison of two protocols for the generation of iPSC-derived human astrocytes. Biol Proced Online. 2023;25:26 pubmed publisher
Militi S, Nibhani R, Jalali M, Pauklin S. RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling. Cell Rep. 2023;42:113146 pubmed publisher
Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, et al. Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids. bioRxiv. 2023;: pubmed publisher
Jourdon A, Wu F, Mariani J, Capauto D, Norton S, Tomasini L, et al. Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis. Nat Neurosci. 2023;26:1505-1515 pubmed publisher
Cunningham D, Stanberry I, Ye S, Alonzo M, Zhao M, Garg V, et al. Generation of iPSC line NCHi012-A from a patient with Alagille syndrome and heterozygous pathogenic variant in the JAG1 gene. Stem Cell Res. 2023;71:103177 pubmed publisher
Girgin M, Broguiere N, Mattolini L, Lutolf M. A New Approach to Generate Gastruloids to Develop Anterior Neural Tissues. Bio Protoc. 2023;13:e4722 pubmed publisher
Qiu J, Liu Y, Wei H, Zeng F, Yan J. Single-cell RNA sequencing of neural stem cells derived from human trisomic iPSCs reveals the abnormalities during neural differentiation of Down syndrome. Front Mol Neurosci. 2023;16:1137123 pubmed publisher
CUKIER H, Duarte C, Laverde Paz M, Simon S, Van Booven D, Miyares A, et al. An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. bioRxiv. 2023;: pubmed publisher
Isoda M, Sanosaka T, Tomooka R, Mabuchi Y, Shinozaki M, Andoh Noda T, et al. Mesenchymal properties of iPSC-derived neural progenitors that generate undesired grafts after transplantation. Commun Biol. 2023;6:611 pubmed publisher
Zhu Z, Chen X, Guo A, Manzano T, Walsh P, Wills K, et al. Mitotic bookmarking by SWI/SNF subunits. Nature. 2023;618:180-187 pubmed publisher
Chang S, Wu T, Shih Y, Chen Y, Su H, Chian C, et al. SOX1 Functions as a Tumor Suppressor by Repressing HES1 in Lung Cancer. Cancers (Basel). 2023;15: pubmed publisher
Sidhaye J, Trepte P, Sepke N, Novatchkova M, Schutzbier M, D xfc rnberger G, et al. Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids. elife. 2023;12: pubmed publisher
Grigor eva E, Kopytova A, Yarkova E, Pavlova S, Sorogina D, Malakhova A, et al. Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson's Disease. Int J Mol Sci. 2023;24: pubmed publisher
Castellanos Montiel M, Chaineau M, Franco Flores A, Haghi G, Carrillo Valenzuela D, Reintsch W, et al. An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids. Cells. 2023;12: pubmed publisher
Sun J, Osenberg S, Irwin A, Ma L, Lee N, Xiang Y, et al. Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation. Cell Rep. 2023;42:111942 pubmed publisher
Yelagandula R, Stecher K, Novatchkova M, Michetti L, Michlits G, Wang J, et al. ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers. Nat Cell Biol. 2023;25:42-55 pubmed publisher
Li L, Si X, Yang J, Lei M, Liu H, Ruan J, et al. Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation. Stem Cell Res. 2023;66:102995 pubmed publisher
Czerminski J, King O, Lawrence J. Large-scale organoid study suggests effects of trisomy 21 on early fetal neurodevelopment are more subtle than variability between isogenic lines and experiments. Front Neurosci. 2022;16:972201 pubmed publisher
Brady M, Mariani J, Koca Y, Szekely A, King R, Bloch M, et al. Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids. Mol Psychiatry. 2022;27:5007-5019 pubmed publisher
Lin H, Ye S, Xu Z, Penaloza J, Aljuhani M, Vetter T, et al. Generation and characterization of a human induced pluripotent stem cell (iPSC) line from a patient with congenital heart disease (CHD). Stem Cell Res. 2022;65:102958 pubmed publisher
Kim J, Muraoka M, Okada H, Toyoda A, Ajima R, Saga Y. The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing. PLoS Genet. 2022;18:e1009967 pubmed publisher
Gogolou A, Souilhol C, Granata I, Wymeersch F, Manipur I, Wind M, et al. Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor. elife. 2022;11: pubmed publisher
Sun J, Cai Q, Xu M, Liu Y, Li W, Li J, et al. Loss of Protein Function Causing Severe Phenotypes of Female-Restricted Wieacker Wolff Syndrome due to a Novel Nonsense Mutation in the ZC4H2 Gene. Genes (Basel). 2022;13: pubmed publisher
Zheng Y, Gallegos C, Xue H, Li S, Kim D, Zhou H, et al. Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Promotes Forelimb Functional Recovery after Cervical Spinal Cord Injury. Cells. 2022;11: pubmed publisher
Tischler J, Swank Z, Hsiung H, Vianello S, Lutolf M, Maerkl S. An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates. Cell Rep Methods. 2022;2:100244 pubmed publisher
Robinson H, Ali S, Díaz Hernández M, López González R. Telomere Attrition in Induced Pluripotent Stem Cell-Derived Neurons From ALS/FTD-Related C9ORF72 Repeat Expansion Carriers. Front Cell Dev Biol. 2022;10:874323 pubmed publisher
Nehme R, Pietil xe4 inen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, et al. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia. Nat Commun. 2022;13:3690 pubmed publisher
Cho H, Abshire E, Popp M, Pr xf6 schel C, Schwartz J, Yeo G, et al. AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay. Mol Cell. 2022;82:2779-2796.e10 pubmed publisher
Mencke P, Boussaad I, Onal G, Kievit A, Boon A, Mandemakers W, et al. Generation and characterization of a genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A). Stem Cell Res. 2022;62:102792 pubmed publisher
Xu J, Huang L, Fang Z, Luo H, Chen Y, Li Y, et al. Spinal dI4 Interneuron Differentiation From Human Pluripotent Stem Cells. Front Mol Neurosci. 2022;15:845875 pubmed publisher
Tisch M, Carmen De Mingo Alemany M, Suarez Cubero M, Fauth C, Defrancesco M, Zschocke J, et al. Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene. Stem Cell Res. 2022;61:102784 pubmed publisher
Kodani Y, Kawata M, Suga H, Kaneko Y, Nakashima A, Kameyama T, et al. Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells. Eneuro. 2022;9: pubmed publisher
Garipler G, Lu C, Morrissey A, Lopez Zepeda L, Pei Y, Vidal S, et al. The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes. Cell Rep. 2022;38:110524 pubmed publisher
Zyner K, Simeone A, Flynn S, Doyle C, Marsico G, Adhikari S, et al. G-quadruplex DNA structures in human stem cells and differentiation. Nat Commun. 2022;13:142 pubmed publisher
Meharena H, Marco A, Dileep V, Lockshin E, Akatsu G, Mullahoo J, et al. Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors. Cell Stem Cell. 2022;29:116-130.e7 pubmed publisher
Hong J, Cheng Y, Yang S, Swaroop M, Xu M, Beers J, et al. iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II. Exp Cell Res. 2022;412:113007 pubmed publisher
Fathi A, Mathivanan S, Kong L, Petersen A, Harder C, Block J, et al. Chemically induced senescence in human stem cell-derived neurons promotes phenotypic presentation of neurodegeneration. Aging Cell. 2021;:e13541 pubmed publisher
Ciarpella F, Zamfir R, Campanelli A, Ren E, Pedrotti G, Bottani E, et al. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. iScience. 2021;24:103438 pubmed publisher
Li J, Chen L, Li D, Lu M, Huang X, Han X, et al. Electroacupuncture Promotes the Survival of the Grafted Human MGE Neural Progenitors in Rats with Cerebral Ischemia by Promoting Angiogenesis and Inhibiting Inflammation. Neural Plast. 2021;2021:4894881 pubmed publisher
Mackinlay K, Weatherbee B, Souza Rosa V, Handford C, Hudson G, Coorens T, et al. An in vitro stem cell model of human epiblast and yolk sac interaction. elife. 2021;10: pubmed publisher
Pachano T, S xe1 nchez Gaya V, Ealo T, Mariner Faul xed M, Bleckwehl T, Asenjo H, et al. Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness. Nat Genet. 2021;53:1036-1049 pubmed publisher
Kawatani K, Nambara T, Nawa N, Yoshimatsu H, Kusakabe H, Hirata K, et al. A human isogenic iPSC-derived cell line panel identifies major regulators of aberrant astrocyte proliferation in Down syndrome. Commun Biol. 2021;4:730 pubmed publisher
Dykxhoorn D, Tong X, Gosstola N, Liu X. Derivation of iPSC line UMi029-A bearing a hearing-loss associated variant in the SMPX gene. Stem Cell Res. 2021;54:102405 pubmed publisher
Kim K, Li C, Bunina D, Jeong H, Ghelman J, Yoon J, et al. Donor cell memory confers a metastable state of directly converted cells. Cell Stem Cell. 2021;28:1291-1306.e10 pubmed publisher
Krenn V, Bosone C, Burkard T, Spanier J, Kalinke U, Calistri A, et al. Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell. 2021;28:1362-1379.e7 pubmed publisher
Prince L, Neely M, Warren E, Thomas M, Henley M, Smith K, et al. Environmentally relevant developmental methylmercury exposures alter neuronal differentiation in a human-induced pluripotent stem cell model. Food Chem Toxicol. 2021;152:112178 pubmed publisher
Gong C, Zheng X, Guo F, Wang Y, Zhang S, Chen J, et al. Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury. Cell Rep. 2021;34:108889 pubmed publisher
Wang M, Li A, Sekiya M, Beckmann N, Quan X, Schrode N, et al. Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. Neuron. 2021;109:257-272.e14 pubmed publisher
Minn K, Fu Y, He S, Dietmann S, George S, Anastasio M, et al. High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures. elife. 2020;9: pubmed publisher
Malankhanova T, Suldina L, Grigor eva E, Medvedev S, Minina J, Morozova K, et al. A Human Induced Pluripotent Stem Cell-Derived Isogenic Model of Huntington's Disease Based on Neuronal Cells Has Several Relevant Phenotypic Abnormalities. J Pers Med. 2020;10: pubmed publisher
Wörsdörfer P, Rockel A, Alt Y, Kern A, Ergun S. Generation of Vascularized Neural Organoids by Co-culturing with Mesodermal Progenitor Cells. STAR Protoc. 2020;1:100041 pubmed publisher
Lundin A, Porritt M, Jaiswal H, Seeliger F, Johansson C, Bidar A, et al. Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery. Nat Commun. 2020;11:4903 pubmed publisher
Dias J, Alekseenko Z, Jeggari A, Boareto M, Vollmer J, Kozhevnikova M, et al. A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells. Sci Adv. 2020;6: pubmed publisher
Hirata K, Nambara T, Kawatani K, Nawa N, Yoshimatsu H, Kusakabe H, et al. 4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates. Sci Rep. 2020;10:14047 pubmed publisher
Walsh P, Truong V, Nayak S, Sald xed as Montivero M, Low W, Parr A, et al. Accelerated differentiation of human pluripotent stem cells into neural lineages via an early intermediate ectoderm population. Stem Cells. 2020;38:1400-1408 pubmed publisher
Martins S, Müller Schiffmann A, Erichsen L, Bohndorf M, Wruck W, Sleegers K, et al. IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network. Int J Mol Sci. 2020;21: pubmed publisher
Meraviglia V, Arendzen C, Tok M, Freund C, Maione A, Sommariva E, et al. Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation. Stem Cell Res. 2020;46:101835 pubmed publisher
Lewis E, Sankar S, Tong C, Patterson E, Waller L, Gontarz P, et al. Geminin is required for Hox gene regulation to pattern the developing limb. Dev Biol. 2020;464:11-23 pubmed publisher
Meraviglia V, Arendzen C, Freund C, Atsma D, Mummery C, Bellin M. Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene. Stem Cell Res. 2020;45:101764 pubmed publisher
Berenguer Escuder C, Grossmann D, Antony P, Arena G, Wasner K, Massart F, et al. Impaired mitochondrial-endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson's disease. Hum Mol Genet. 2020;29:1353-1364 pubmed publisher
Bredenkamp N, Yang J, Clarke J, Stirparo G, von Meyenn F, Dietmann S, et al. Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency. Stem Cell Reports. 2019;13:1083-1098 pubmed publisher
Wörsdörfer P, Dalda N, Kern A, Kruger S, Wagner N, Kwok C, et al. Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells. Sci Rep. 2019;9:15663 pubmed publisher
Di Stefano B, Luo E, Haggerty C, Aigner S, Charlton J, Brumbaugh J, et al. The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell. 2019;25:622-638.e13 pubmed publisher
Kim J, Lana B, Torelli S, Ryan D, Catapano F, Ala P, et al. A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan. EMBO Rep. 2019;20:e47967 pubmed publisher
Stuart H, Stirparo G, Lohoff T, Bates L, Kinoshita M, Lim C, et al. Distinct Molecular Trajectories Converge to Induce Naive Pluripotency. Cell Stem Cell. 2019;25:388-406.e8 pubmed publisher
Park S, Yoo J, Lee D, Jang J, Cho M, Kim D, et al. Establishment of PITX3-mCherry knock-in reporter human embryonic stem cell line (WAe009-A-23). Stem Cell Res. 2019;39:101499 pubmed publisher
Liu Z, Osipovitch M, Benraiss A, Huynh N, Foti R, Bates J, et al. Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling. Cell Rep. 2019;27:3832-3843.e6 pubmed publisher
Huang M, Tailor J, Zhen Q, Gillmor A, Miller M, Weishaupt H, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. 2019;: pubmed publisher
Chanda S, Ang C, Lee Q, Ghebrial M, Haag D, Shibuya Y, et al. Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. Cell Stem Cell. 2019;: pubmed publisher
Ang C, Ma Q, Wapinski O, Fan S, Flynn R, Lee Q, et al. The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders. elife. 2019;8: pubmed publisher
Li J, Narayanan C, Bian J, Sambo D, Brickler T, Zhang W, et al. A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family. PLoS ONE. 2018;13:e0208110 pubmed publisher
Kang Y, Ai Z, Duan K, Si C, Wang Y, Zheng Y, et al. Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys. Cell Rep. 2018;25:2563-2576.e9 pubmed publisher
Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, et al. Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury. Stem Cells Transl Med. 2019;8:260-270 pubmed publisher
Lager A, Corradin O, Cregg J, Elitt M, Shick H, Clayton B, et al. Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells. Nat Commun. 2018;9:3708 pubmed publisher
Senft A, Costello I, King H, Mould A, Bikoff E, Robertson E. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming. Cell Rep. 2018;24:1977-1985.e7 pubmed publisher
Latchoumane C, Jackson L, Sendi M, Tehrani K, Mortensen L, Stice S, et al. Chronic Electrical Stimulation Promotes the Excitability and Plasticity of ESC-derived Neurons following Glutamate-induced Inhibition In vitro. Sci Rep. 2018;8:10957 pubmed publisher
Pastor W, Liu W, Chen D, Ho J, Kim R, Hunt T, et al. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nat Cell Biol. 2018;20:553-564 pubmed publisher
Kim J, Lee J, Hwang H, Lee D, Park C, Jung S, et al. Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Exp Mol Med. 2018;50:24 pubmed publisher
Corsini N, Peer A, Moeseneder P, Roiuk M, Burkard T, Theussl H, et al. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 2018;22:543-558.e12 pubmed publisher
Zhang M, Ngo J, Pirozzi F, Sun Y, Wynshaw Boris A. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther. 2018;9:67 pubmed publisher
Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed publisher
Walsh P, Truong V, Hill C, Stoflet N, Baden J, Low W, et al. Defined Culture Conditions Accelerate Small-molecule-assisted Neural Induction for the Production of Neural Progenitors from Human-induced Pluripotent Stem Cells. Cell Transplant. 2017;26:1890-1902 pubmed publisher
Li Y, Wang R, Qiao N, Peng G, Zhang K, Tang K, et al. Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells. J Biol Chem. 2017;292:19590-19604 pubmed publisher
Yuan X, Li Z, Baines A, Gavriilaki E, Ye Z, Wen Z, et al. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. PLoS ONE. 2017;12:e0174074 pubmed publisher
Nevin Z, Factor D, Karl R, Douvaras P, Laukka J, Windrem M, et al. Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes. Am J Hum Genet. 2017;100:617-634 pubmed publisher
Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, et al. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS ONE. 2017;12:e0171947 pubmed publisher
Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed publisher
Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed publisher
Flores J, Cordero Espinoza L, Oeztuerk Winder F, Andersson Rolf A, Selmi T, Blanco S, et al. Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility. Stem Cell Reports. 2017;8:112-124 pubmed publisher
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product information
brand :
R&D Systems
master code :
AF3369
SKU :
AF3369
product name :
Human/Mouse/Rat SOX1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat SOX1 Antibody from R&D Systems is a goat polyclonal antibody to SOX1. This antibody reacts with human,mouse,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),rabbit,rat,xenograft. The Human/Mouse/Rat SOX1 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Bioassay,IHC/IF,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western.
target :
SOX1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 3-15 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human SOX1, Asn242-Gly379 (Leu276Ile), Accession # NP_005977
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Rabbit,Rat,Xenograft
specificity :
Detects human SOX1 in direct ELISAs and Western blots.
gene symbol :
SOX1
top caption :
Detection of Human SOX1 antibody by Western Blot.
accessionNumbers :
NP_005977
applications :
Simple Western,Bioassay,IHC/IF,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
SRY (sex determining region Y)-box 1, SRY-related HMG-box gene 1, transcription factor SOX-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.