Human CD117/c-kit Antibody | R&D Systems AF332 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD117/c-kit Antibody

catalog :

AF332

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 9

Reference
Phua R, Tien T, Goh G, Pantelireis N, Sim K, Lim J, et al. In vitro quantification of pigment production and transfer in 2D co-cultures and 3D skin organotypic. STAR Protoc. 2023;4:102334 pubmed publisher
Luo S, Tang L, Zhou D, Bo H, Fan L. FOXP4 promotes proliferation of human spermatogonial stem cells. Asian J Androl. 2023;25:322-330 pubmed publisher
Pfeiffer A, Petersen J, Falduto G, Anderson D, Zimmerberg J, Metcalfe D, et al. Selective immunocapture reveals neoplastic human mast cells secrete distinct microvesicle- and exosome-like populations of KIT-containing extracellular vesicles. J Extracell Vesicles. 2022;11:e12272 pubmed publisher
Lu P, Chen J, Zhang C, Saur D, Baer C, Lifshitz L, et al. Oscillating calcium signals in smooth muscle cells underlie the persistent basal tone of internal anal sphincter. J Cell Physiol. 2021;236:5937-5952 pubmed publisher
Cui W, He X, Zhai X, Zhang H, Zhang Y, Jin F, et al. CARF promotes spermatogonial self-renewal and proliferation through Wnt signaling pathway. Cell Discov. 2020;6:85 pubmed publisher
Drimousis S, Markus I, Murphy T, Perera D, Phan Thien K, Zhang L, et al. Gender-Related Differences of Tachykinin NK2 Receptor Expression and Activity in Human Colonic Smooth Muscle. J Pharmacol Exp Ther. 2020;375:28-39 pubmed publisher
Shami A, Zheng X, Munyoki S, Ma Q, Manske G, Green C, et al. Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis. Dev Cell. 2020;54:529-547.e12 pubmed publisher
Guo J, Nie X, Giebler M, Mlcochova H, Wang Y, Grow E, et al. The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty. Cell Stem Cell. 2020;26:262-276.e4 pubmed publisher
Tang R, Fan L. PLZFposc-KITpos-delineated A1-A4-differentiating spermatogonia by subset and stage detection upon Bouin fixation. Asian J Androl. 2019;21:309-318 pubmed publisher

product information

brand :

R&D Systems

master code :

AF332

SKU :

AF332

product name :

Human CD117/c-kit Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human CD117/c-kit Antibody from R&D Systems is a goat polyclonal antibody to CD117/c-kit. This antibody reacts with human,mouse. The Human CD117/c-kit Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Flow Cytometry,Simple Western,Neutralization,CyTOF-ready.

target :

CD117/c-kit

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 5 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Neutralization 0.06-0.36 ug/mL, CyTOF-ready

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD117/c-kit, Gln26-Thr520, Accession # P10721

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human and mouse CD117/c-kit in direct ELISAs and Western blots. In Western blots, approximately 2% cross-reactivity with recombinant human PDGF sR alpha is observed.

gene symbol :

KIT

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by SCF/c-kit Ligand and Neutralization by Human CD117/c-kit Antibody.

accessionNumbers :

P10721

applications :

Flow Cytometry,Simple Western,Neutralization,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

519 USD

alt names :

CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage