Human XPE/DDB2 Antibody | R&D Systems AF3297 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human XPE/DDB2 Antibody

catalog :

AF3297

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Kusakabe M, Sugasawa K. Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cells. STAR Protoc. 2023;4:102378 pubmed publisher
Blessing C, Apelt K, van den Heuvel D, González Leal C, Rother M, van der Woude M, et al. XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair. Nat Commun. 2022;13:4762 pubmed publisher
Kusakabe M, Kakumu E, Kurihara F, Tsuchida K, Maeda T, Tada H, et al. Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein. iScience. 2022;25:104040 pubmed publisher
Sakai W, Yuasa Sunagawa M, Kusakabe M, Kishimoto A, Matsui T, Kaneko Y, et al. Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair. Sci Rep. 2020;10:19704 pubmed publisher
Lai T, Hu M. Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism. Sci Rep. 2019;9:5304 pubmed publisher
Zhu Q, Wei S, Sharma N, Wani G, He J, Wani A. Human CRL4DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1. Oncotarget. 2017;8:104525-104542 pubmed publisher

product information

master code :

AF3297

SKU :

AF3297

product name :

Human XPE/DDB2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human XPE/DDB2 Antibody from R&D Systems is a goat polyclonal antibody to XPE/DDB2. This antibody reacts with human. The Human XPE/DDB2 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.

target :

XPE/DDB2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human XPE/DDB2, Met1-Lys427, Accession # Q92466

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human XPE/DDB2 in Western blots.

gene symbol :

DDB2

top caption :

Detection of Human XPE/DDB2 antibody by Western Blot.

accessionNumbers :

Q92466

applications :

Western Blot,Immunocytochemistry

USD :

469 USD

alt names :

damage-specific DNA binding protein 2 (48kD), damage-specific DNA binding protein 2, 48kDa, Damage-specific DNA-binding protein 2, DDB p48 subunit, DDB2, DDBb, DNA damage-binding protein 2, FLJ34321, UV-damaged DNA-binding protein 2, UV-DDB 2, UV-DDB2, xeroderma pigmentosum group E protein, XP5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage