product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Aurora A Antibody
catalog :
AF3295
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Chang Y, Cheung C, Kuo Y. Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells. Front Cell Dev Biol. 2020;8:485 pubmed publisher
Wander S, Cohen O, Gong X, Johnson G, Buendia Buendia J, Lloyd M, et al. The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer. Cancer Discov. 2020;10:1174-1193 pubmed publisher
Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, et al. Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy. Mol Cancer Ther. 2019;18:2207-2219 pubmed publisher
Gong X, Du J, Parsons S, Merzoug F, Webster Y, Iversen P, et al. Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene. Cancer Discov. 2019;9:248-263 pubmed publisher
product information
master code :
AF3295
SKU :
AF3295
product name :
Human Aurora A Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Aurora A Antibody from R&D Systems is a goat polyclonal antibody to Aurora A. This antibody reacts with human. The Human Aurora A Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Simple Western.
target :
Aurora A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human Aurora A, Met1-Glu131, Accession # O14965
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Aurora A in Western blots.
gene symbol :
AURKA
top caption :
Detection of Human Aurora A antibody by Western Blot.
accessionNumbers :
O14965
applications :
Western Blot,Immunocytochemistry,Simple Western
USD :
469 USD
alt names :
AIK, AIKAurA, ARK1, ARK-1, ARK1EC 2.7.11.1, AURA, AURKA, aurora kinase AhARK1, aurora/IPL1-like kinase, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, Breast tumor-amplified kinase, breast-tumor-amplified kinase, BTAK, BTAKAURORA2, EC 2.7.11, IPL1-related kinase, serine/threonine kinase 6, serine/threonine protein kinase 15, Serine/threonine-protein kinase 15, serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, STK15, STK15serine/threonine kinase 15, STK6, STK6MGC34538, STK7
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.