Human Cadherin-13 Antibody | R&D Systems AF3264 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Cadherin-13 Antibody

catalog :

AF3264

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:200; loading ...; fig 4a	Jansch C, Ziegler G, Forero A, Gredy S, W xe4 ldchen S, Vitale M, et al. Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. J Neural Transm (Vienna). 2021;128:225-241 pubmed publisher
	Fujii K, Fujishima Y, Kita S, Kawada K, Fukuoka K, Sakaue T, et al. Pharmacological HIF-1 activation upregulates extracellular vesicle production synergistically with adiponectin through transcriptional induction and protein stabilization of T-cadherin. Sci Rep. 2024;14:3620 pubmed publisher
	Fukuoka K, Mineo R, Kita S, Fukuda S, Okita T, Kawada Horitani E, et al. ER stress decreases exosome production through adiponectin/T-cadherin-dependent and -independent pathways. J Biol Chem. 2023;299:105114 pubmed publisher
	Okita T, Kita S, Fukuda S, Fukuoka K, Kawada Horitani E, Iioka M, et al. Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling. iScience. 2022;25:105404 pubmed publisher
	Vitale M, Zöller J, Jansch C, Janz A, Edenhofer F, Klopocki E, et al. Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelopmental disorders using CRISPR/Cas9. Stem Cell Res. 2021;51:102169 pubmed publisher
	Nakamura Y, Kita S, Tanaka Y, Fukuda S, Obata Y, Okita T, et al. Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice. Mol Ther. 2020;28:2203-2219 pubmed publisher
	Kita S, Fukuda S, Maeda N, Shimomura I. Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin. elife. 2019;8: pubmed publisher
	Mori D, Miyagawa S, Matsuura R, Sougawa N, Fukushima S, Ueno T, et al. Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotype. Cardiovasc Diabetol. 2019;18:39 pubmed publisher
	Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
	Frismantiene A, Kyriakakis E, Dasen B, Erne P, Resink T, Philippova M. Actin cytoskeleton regulates functional anchorage-migration switch during T-cadherin-induced phenotype modulation of vascular smooth muscle cells. Cell Adh Migr. 2018;12:69-85 pubmed publisher
	Fukuda S, Kita S, Obata Y, Fujishima Y, Nagao H, Masuda S, et al. The unique prodomain of T-cadherin plays a key role in adiponectin binding with the essential extracellular cadherin repeats 1 and 2. J Biol Chem. 2017;292:7840-7849 pubmed publisher
	Alexander G, Huang Y, Soderblom E, He X, Moseley M, McNamara J. Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex. J Neurochem. 2017;140:629-644 pubmed publisher
	Buechner S, Erne P, Resink T. T-Cadherin Expression in the Epidermis and Adnexal Structures of Normal Skin. Dermatopathology (Basel). 2016;3:68-78 pubmed

product information

brand :

R&D Systems

master code :

AF3264

SKU :

AF3264

product name :

Human Cadherin-13 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human Cadherin-13 Antibody from R&D Systems is a goat polyclonal antibody to Cadherin-13. This antibody reacts with human,mouse,rat. The Human Cadherin-13 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,Simple Western,CyTOF-ready.

target :

Cadherin-13

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL, CyTOF-ready

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Cadherin-13, Glu23-Ala692, Accession # P55290

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human Cadherin-13 in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant mouse Cadherin-13 is observed, and less than 10% cross-reactivity with recombinant human (rh) N-Cadherin is observed, and less than 2% cross-reactivity with rhCadherin-8, rhCadherin-11, rhCadherin-17, rhE-Cadherin, rhP-Cadherin, rhVE-Cadherin and rhR-Cadherin is observed.

gene symbol :

CDH13

top caption :

Detection of Human Cadherin-13 antibody by Western Blot.

accessionNumbers :

P55290

applications :

Flow Cytometry,Simple Western,CyTOF-ready,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

509 USD

alt names :

cadherin 13, H-cadherin (heart), cadherin-13, Cadherin13, CDH13, CDHHT-cadherin, H-cadherin, Heart cadherin, heart-cadherin, P105, T-cad, T-Cadherin, Truncated cadherin, truncated-cadherin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage