Human/Mouse/Rat Neurofascin Antibody | R&D Systems AF3235 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Neurofascin Antibody

catalog :

AF3235

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 28

Reference
Ogawa Y, Lim B, George S, Oses Prieto J, Rasband J, Eshed Eisenbach Y, et al. Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nat Commun. 2023;14:6797 pubmed publisher
Miguel Hidalgo J, Hearn E, Moulana M, Saleem K, Clark A, Holmes M, et al. Reduced length of nodes of Ranvier and altered proteoglycan immunoreactivity in prefrontal white matter in major depressive disorder and chronically stressed rats. Sci Rep. 2023;13:16419 pubmed publisher
Dustin E, Suárez Pozos E, Stotesberry C, Qiu S, Palavicini J, Han X, et al. Compromised Myelin and Axonal Molecular Organization Following Adult-Onset Sulfatide Depletion. Biomedicines. 2023;11: pubmed publisher
Ogawa Y, Lim B, George S, Oses Prieto J, Rasband J, Eshed Eisenbach Y, et al. Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments. bioRxiv. 2023;: pubmed publisher
Miller J, Drouet D, Yermakov L, Elbasiouny M, Bensabeur F, Bottomley M, et al. Distinct Changes in Calpain and Calpastatin during PNS Myelination and Demyelination in Rodent Models. Int J Mol Sci. 2022;23: pubmed publisher
Shackleford G, Marziali L, Sasaki Y, Claessens A, Ferri C, Weinstock N, et al. A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication. PLoS Genet. 2022;18:e1010477 pubmed publisher
. Diabetes Mellitus Is a Possible Risk Factor for Nodo-paranodopathy With Antiparanodal Autoantibodies. Neurol Neuroimmunol Neuroinflamm. 2022;9: pubmed publisher
Stevens S, Longley C, Ogawa Y, Teliska L, Arumanayagam A, Nair S, et al. Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K+ channels. elife. 2021;10: pubmed publisher
Della Flora Nunes G, Wilson E, Marziali L, Hurley E, Silvestri N, He B, et al. Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells. Nat Commun. 2021;12:3285 pubmed publisher
Chang K, Agrawal I, Vainshtein A, Ho W, Xin W, Tucker Kellogg G, et al. TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. elife. 2021;10: pubmed publisher
Pourhoseini S, Goswami Sewell D, ZUNIGA SANCHEZ E. Neurofascin Is a Novel Component of Rod Photoreceptor Synapses in the Outer Retina. Front Neural Circuits. 2021;15:635849 pubmed publisher
Ogawa Y, Rasband M. Endogenously expressed Ranbp2 (Nup358) is not at the axon initial segment. J Cell Sci. 2021;: pubmed publisher
Feng T, Mai S, Roscoe J, Sheng R, Ullah M, Zhang J, et al. Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice. EMBO Rep. 2020;21:e50219 pubmed publisher
Davies A, Fehmi J, Senel M, Tumani H, Dorst J, Rinaldi S. Immunoadsorption and Plasma Exchange in Seropositive and Seronegative Immune-Mediated Neuropathies. J Clin Med. 2020;9: pubmed publisher
Zhang Y, Yuen S, Peles E, Salzer J. Accumulation of Neurofascin at Nodes of Ranvier Is Regulated by a Paranodal Switch. J Neurosci. 2020;40:5709-5723 pubmed publisher
Liu C, Seo R, Ho T, Stankewich M, Mohler P, Hund T, et al. β spectrin-dependent and domain specific mechanisms for Na+ channel clustering. elife. 2020;9: pubmed publisher
Mart xed n Aguilar L, Pascual Go xf1 i E, Lleix xe0 C, Frasquet M, Argente H, Cano Abascal Á, et al. Antibodies against nodo-paranodal proteins are not present in genetic neuropathies. Neurology. 2020;95:e427-e433 pubmed publisher
Liu C, Stevens S, Teliska L, Stankewich M, Mohler P, Hund T, et al. Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity. elife. 2020;9: pubmed publisher
Xu H, Dzhashiashvili Y, Shah A, Kunjamma R, Weng Y, Elbaz B, et al. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020;105:293-309.e5 pubmed publisher
Hamdan H, Lim B, Torii T, Joshi A, Konning M, Smith C, et al. Mapping axon initial segment structure and function by multiplexed proximity biotinylation. Nat Commun. 2020;11:100 pubmed publisher
Torii T, Ogawa Y, Liu C, Ho T, Hamdan H, Wang C, et al. NuMA1 promotes axon initial segment assembly through inhibition of endocytosis. J Cell Biol. 2020;219: pubmed publisher
Yermakov L, GRIGGS R, Drouet D, Sugimoto C, Williams M, Vorhees C, et al. Impairment of cognitive flexibility in type 2 diabetic db/db mice. Behav Brain Res. 2019;371:111978 pubmed publisher
Wang C, Ortiz Gonzalez X, Yum S, Gill S, White A, Kelter E, et al. βIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy. Am J Hum Genet. 2018;102:1158-1168 pubmed publisher
Susuki K, Zollinger D, Chang K, Zhang C, Huang C, Tsai C, et al. Glial βII Spectrin Contributes to Paranode Formation and Maintenance. J Neurosci. 2018;38:6063-6075 pubmed publisher
GRIGGS R, Yermakov L, Drouet D, Nguyen D, Susuki K. Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation. ASN Neuro. 2018;10:1759091418766175 pubmed publisher
Querol L, Siles A, Alba Rovira R, Jáuregui A, Devaux J, Faivre Sarrailh C, et al. Antibodies against peripheral nerve antigens in chronic inflammatory demyelinating polyradiculoneuropathy. Sci Rep. 2017;7:14411 pubmed publisher
Huang C, Zhang C, Zollinger D, Leterrier C, Rasband M. An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration. J Neurosci. 2017;37:11323-11334 pubmed publisher
Amor V, Zhang C, Vainshtein A, Zhang A, Zollinger D, Eshed Eisenbach Y, et al. The paranodal cytoskeleton clusters Na+ channels at nodes of Ranvier. elife. 2017;6: pubmed publisher

product information

brand :

R&D Systems

master code :

AF3235

SKU :

AF3235

product name :

Human/Mouse/Rat Neurofascin Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat Neurofascin Antibody from R&D Systems is a chicken polyclonal antibody to Neurofascin. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Mouse/Rat Neurofascin Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Western Blot,Bioassay,Biotinylation.

target :

Neurofascin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL

host :

Chicken

immunogen :

Mouse myeloma cell line NS0-derived recombinant rat Neurofascin, Ile25-Ala1031, Accession # NP_446361

isotype :

IgY

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects human, mouse, rat Neurofascin in Western blots and rat Neurofascin in direct ELISAs.

gene symbol :

NFASC

top caption :

Detection of Human, Mouse, and Rat Neurofascin antibody by Western Blot.

accessionNumbers :

NP_446361

applications :

Bioassay,Biotinylation,Immunohistochemistry,Western Blot,Immunocytochemistry

USD :

509 USD

alt names :

DKFZp686P2250, KIAA0756FLJ46866, neurofascin, neurofascin homolog, neurofascin homolog (chicken), NF, NFASC, NRCAML

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage