product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat AMPK alpha 1 Antibody
catalog :
AF3197
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 10
Reference
Zhai R, Liu Y, Tong J, Yu Y, Yang L, Gu Y, et al. Empagliflozin Ameliorates Preeclampsia and Reduces Postpartum Susceptibility to Adriamycin in a Mouse Model Induced by Angiotensin Receptor Agonistic Autoantibodies. Front Pharmacol. 2022;13:826792 pubmed publisher
Eacret D, Noreck J, Blendy J. Adenosine Monophosphate-activated Protein Kinase (AMPK) in serotonin neurons mediates select behaviors during protracted withdrawal from morphine in mice. Behav Brain Res. 2022;419:113688 pubmed publisher
Shin H, Yang W, Chay D, Lee E, Chung J, Kim H, et al. Tetraspanin 1 promotes endometriosis leading to ovarian clear cell carcinoma. Mol Oncol. 2020;: pubmed publisher
Yang W, Shin H, Cho H, Chung J, Lee E, Kim J, et al. TOM40 Inhibits Ovarian Cancer Cell Growth by Modulating Mitochondrial Function Including Intracellular ATP and ROS Levels. Cancers (Basel). 2020;12: pubmed publisher
Yang W, Zhou X, Zimmermann H, Ma T. Brain-specific suppression of AMPKα2 isoform impairs cognition and hippocampal LTP by PERK-mediated eIF2α phosphorylation. Mol Psychiatry. 2021;26:1880-1897 pubmed publisher
Zimmermann H, Yang W, Kasica N, Zhou X, Wang X, Beckelman B, et al. Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice. J Clin Invest. 2020;130:3511-3527 pubmed publisher
Sagrillo Fagundes L, Bienvenue Pariseault J, Vaillancourt C. Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells. PLoS ONE. 2019;14:e0202458 pubmed publisher
Shi C, Rubel C, Soss S, Sanchez Hodge R, Zhang S, Madrigal S, et al. Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16. PLoS Genet. 2018;14:e1007664 pubmed publisher
Maddocks O, Athineos D, Cheung E, Lee P, Zhang T, van den Broek N, et al. Modulating the therapeutic response of tumours to dietary serine and glycine starvation. Nature. 2017;544:372-376 pubmed publisher
Domise M, Didier S, Marinangeli C, Zhao H, Chandakkar P, Buée L, et al. AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo. Sci Rep. 2016;6:26758 pubmed publisher
product information
master code :
AF3197
SKU :
AF3197
product name :
Human/Mouse/Rat AMPK alpha 1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat AMPK alpha 1 Antibody from R&D Systems is a goat polyclonal antibody to AMPK alpha 1. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat AMPK alpha 1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Bioassay,Immunoprecipitation,Immunocytochemistry.
target :
AMPK alpha 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human AMPK alpha 1, Lys349-Gln559, Accession # Q13131
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat AMPK alpha 1 in Western blots. The antibody does not cross-react with recombinant human AMPK alpha 2.
gene symbol :
PRKAA1
top caption :
AMPKa1 antibody in Human Liver by Immunohistochemistry (IHC-P).
accessionNumbers :
Q13131
applications :
Immunohistochemistry,Western Blot,Bioassay,Immunoprecipitation,Immunocytochemistry
USD :
469 USD
alt names :
AMP -activate kinase alpha 1 subunit, AMP-activated protein kinase, catalytic, alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK, AMPK alpha 1,5'-AMP-activated protein kinase, catalytic alpha-1 chain, AMPK subunit alpha-1, AMPK1, AMPKa1, EC 2.7.11, EC 2.7.11.1, MGC33776, MGC57364, PRKAA1, protein kinase, AMP-activated, alpha 1 catalytic subunit
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.