product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Myeloperoxidase/MPO Antibody
catalog :
AF3174
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 3
Reference
Reynolds W, Malle E, Maki R. Thiocyanate Reduces Motor Impairment in the hMPO-A53T PD Mouse Model While Reducing MPO-Oxidation of Alpha Synuclein in Enlarged LYVE1/AQP4 Positive Periventricular Glymphatic Vessels. Antioxidants (Basel). 2022;11: pubmed publisher
Maki R, Holzer M, Motamedchaboki K, Malle E, Masliah E, Marsche G, et al. Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment. Free Radic Biol Med. 2019;141:115-140 pubmed publisher
Bossaller L, Christ A, Pelka K, Nündel K, Chiang P, Pang C, et al. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus. J Immunol. 2016;197:1044-53 pubmed publisher
product information
brand :
R&D Systems
master code :
AF3174
SKU :
AF3174
product name :
Human Myeloperoxidase/MPO Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Myeloperoxidase/MPO Antibody from R&D Systems is a goat polyclonal antibody to Myeloperoxidase/MPO. This antibody reacts with human,mouse. The Human Myeloperoxidase/MPO Antibody has been validated for the following applications: ELISA Development,Western Blot,Simple Western,Immunocytochemistry.
target :
Myeloperoxidase/MPO
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Immunocytochemistry 1.7-15 ug/mL
host :
Goat
immunogen :
Human polymorphonuclear leukocytes Myeloperoxidase and mouse myeloma cell line NS0-derived recombinant human Myeloperoxidase/MPO, Ala49-Ser745, Accession # P05164
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human Myeloperoxidase/MPO in direct ELISAs and Western blots. In direct ELISAs, less than 30% cross-reactivity with recombinant mouse MPO is observed and less than 10% cross-reactivity with recombinant human Eosinophil Peroxidase (EPPO) is observed.
gene symbol :
MPO
top caption :
Detection of Human Myeloperoxidase/MPO antibody by Western Blot.
accessionNumbers :
P05164
applications :
Western Blot,Simple Western,Immunocytochemistry,ELISA Development
USD :
519 USD
alt names :
EC 1.11.1, EC 1.11.1.7, MPO, myeloperoxidase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.