Mouse/Rat MyD88 Antibody | R&D Systems AF3109 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse/Rat MyD88 Antibody

catalog :

AF3109

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, proximity ligation assay

more info or order :

R&D Systems product webpage

citations: 12

Reference
Lopez A, Chirasani V, Balan I, O Buckley T, Adelman M, Morrow A. Novel Inhibitory Actions of Neuroactive Steroid [3α,5α]-3-Hydroxypregnan-20-One on Toll-like Receptor 4-Dependent Neuroimmune Signaling. Biomolecules. 2024;14: pubmed publisher
Pereira M, Ramalho T, Andrade W, Durso D, Souza M, Fitzgerald K, et al. The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection. Cell Rep. 2024;43:113795 pubmed publisher
Kalantari P, Shecter I, Hopkins J, Pilotta Gois A, Morales Y, Harandi B, et al. The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology. Proc Natl Acad Sci U S A. 2023;120:e2211047120 pubmed publisher
Pereira M, Durso D, Bryant C, Kurt Jones E, Silverman N, Golenbock D, et al. The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways. Cell Rep. 2022;40:111225 pubmed publisher
Indralingam C, Gutierrez Gonzalez A, Johns S, Tsui T, Cannon D, Fuster M, et al. IL-33/ST2 receptor-dependent signaling in the development of pulmonary hypertension in Sugen/hypoxia mice. Physiol Rep. 2022;10:e15185 pubmed publisher
Parveen A, Bohnert K, Tomaz da Silva M, Wen Y, Bhat R, Roy A, et al. MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms. FASEB J. 2021;35:e21821 pubmed publisher
Deliz Aguirre R, Cao F, Gerpott F, Auevechanichkul N, Chupanova M, Mun Y, et al. MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling. J Cell Biol. 2021;220: pubmed publisher
Li M, Wang H, Li W, Xu X, Yu Y. Macrophage activation on "phagocytic synapse" arrays: Spacing of nanoclustered ligands directs TLR1/2 signaling with an intrinsic limit. Sci Adv. 2020;6: pubmed publisher
Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
Dowling J, Tate M, Rosli S, Bourke N, Bitto N, Lauterbach M, et al. The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses. J Immunol. 2019;202:2384-2396 pubmed publisher
De Nardo D, Balka K, Cardona Gloria Y, Rao V, Latz E, Masters S. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling. J Biol Chem. 2018;293:15195-15207 pubmed publisher
Javmen A, Szmacinski H, Lakowicz J, Toshchakov V. Blocking TIR Domain Interactions in TLR9 Signaling. J Immunol. 2018;201:995-1006 pubmed publisher

product information

master code :

AF3109

SKU :

AF3109

product name :

Mouse/Rat MyD88 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse/Rat MyD88 Antibody from R&D Systems is a goat polyclonal antibody to MyD88. This antibody reacts with human,mouse,rat. The Mouse/Rat MyD88 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Co-Immunoprecipitation,Immunocytochemistry,Proximity Ligation Assay (PLA),Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

MyD88

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse MyD88, Met1-Pro296, Accession # Q3U7M4

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects mouse and rat MyD88 in Western blots.

gene symbol :

MYD88

top caption :

Detection of Mouse/Rat MyD88 antibody by Western Blot.

accessionNumbers :

Q3U7M4

applications :

Western Blot,Co-Immunoprecipitation,Immunoprecipitation,Immunocytochemistry,Proximity Ligation Assay (PLA),Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

489 USD

alt names :

MYD88D, myeloid differentiation primary response gene (88), myeloid differentiation primary response protein MyD88

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage