Human ROBO3 Antibody | R&D Systems AF3076 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ROBO3 Antibody

catalog :

AF3076

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 17

Reference
Herrera A, Menendez A, Ochoa A, Bardia L, Colombelli J, Pons S. Neurogenesis redirects β-catenin from adherens junctions to the nucleus to promote axonal growth. Development. 2023;150: pubmed publisher
Schlienger S, Yam P, Balekoglu N, Ducuing H, Michaud J, Makihara S, et al. Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control. Sci Adv. 2023;9:eadd5501 pubmed publisher
Zang Y, Chaudhari K, Bashaw G. Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputs. Cell Rep. 2022;41:111785 pubmed publisher
Company V, Moreno Cerdá A, Andreu Cervera A, Murcia Ramón R, Almagro García F, Echevarria D, et al. Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus. Front Cell Dev Biol. 2021;9:755729 pubmed publisher
Wurmser M, Muppavarapu M, Tait C, Laumonnerie C, González Castrillón L, Wilson S. Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin. Front Cell Dev Biol. 2021;9:668175 pubmed publisher
Company V, Andreu Cervera A, Madrigal M, Andrés B, Almagro García F, Chedotal A, et al. Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067 pubmed publisher
Chaudhari K, Gorla M, Chang C, Kania A, Bashaw G. Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion. elife. 2021;10: pubmed publisher
Gupta S, Yamauchi K, Novitch B, Butler S. Derivation of dorsal spinal sensory interneurons from human pluripotent stem cells. STAR Protoc. 2021;2:100319 pubmed publisher
Ducuing H, Gardette T, Pignata A, Kindbeiter K, Bozon M, Thoumine O, et al. SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate. elife. 2020;9: pubmed publisher
Roome R, Bourojeni F, Mona B, Rastegar Pouyani S, Blain R, Dumouchel A, et al. Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020;33:108425 pubmed publisher
Zhu Y, Hirata T, Mackay F, Murakami F. Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020;10:11830 pubmed publisher
Skarlatou S, Hérent C, Toscano E, Mendes C, Bouvier J, Zampieri N. Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection. Cell Rep. 2020;31:107741 pubmed publisher
Feng W, Wilkins O, Bang S, Ung M, Li J, An J, et al. CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies. Cell Rep. 2019;29:3405-3420.e5 pubmed publisher
Ferent J, Constable S, Gigante E, Yam P, Mariani L, Legue E, et al. The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance. Cell Rep. 2019;29:3356-3366.e3 pubmed publisher
Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G. Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019;26:3298-3312.e4 pubmed publisher
Andreu Cervera A, Anselme I, Karam A, Laclef C, Catala M, Schneider Maunoury S. The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling. J Neurosci. 2019;39:2398-2415 pubmed publisher
Dominici C, Moreno Bravo J, Puiggros S, Rappeneau Q, Rama N, Vieugué P, et al. Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Nature. 2017;545:350-354 pubmed publisher

product information

master code :

AF3076

SKU :

AF3076

product name :

Human ROBO3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human ROBO3 Antibody from R&D Systems is a goat polyclonal antibody to ROBO3. This antibody reacts with avian - chicken,human,mouse,rat,transgenic mouse. The Human ROBO3 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Immunoprecipitation,Western Blot.

target :

ROBO3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ROBO3, Leu40-Ser545, Accession # Q96MS0

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Avian - Chicken,Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects ROBO3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 60% cross-reactivity with recombinant mouse ROBO3 is observed, 5% cross-reactivity with recombinant human ROBO2 and recombinant rat ROBO1 is observed, and less than 1% cross-reactivity with recombinant human ROBO4 is observed.

gene symbol :

ROBO3

accessionNumbers :

Q96MS0

applications :

Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Immunoprecipitation,Western Blot

USD :

499 USD

alt names :

FLJ21044, HGPPS, HGPS, RBIG1horizontal gaze palsy with progressive scoliosis, retinoblastoma inhibiting gene 1, RIG1, roundabout (axon guidance receptor, Drosophila) homolog 3, roundabout homolog 3, roundabout, axon guidance receptor, homolog 3 (Drosophila), Roundabout-like protein 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage