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company name :
R&D Systems
product type :
antibody
product name :
Human Thrombospondin-1 Antibody
catalog :
AF3074
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 1d
Wiley C, Liu S, Limbad C, Zawadzka A, Beck J, Demaria M, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Rep. 2019;28:3329-3337.e5 pubmed publisher
Catral K, Tse C, Yang W, Ling C, Kwok O, Choy K, et al. Thrombospondin 1 Mediates Autophagy Upon Inhibition of the Rho-Associated Protein Kinase Inhibitor. Cells. 2024;13: pubmed publisher
Mu Y, Wallenius A, Zang G, Zhu S, Rudolfsson S, Aripaka K, et al. The TβRI promotes migration and metastasis through thrombospondin 1 and ITGAV in prostate cancer cells. Oncogene. 2024;43:3321-3334 pubmed publisher
Zhou T, Yang H, Assa C, DeRoo E, Bontekoe J, Burkel B, et al. Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins. bioRxiv. 2024;: pubmed publisher
Niebergall E, Weekley D, Mazur A, Olszewski N, DeSchepper K, Radant N, et al. Abnormal Morphology and Synaptogenic Signaling in Astrocytes Following Prenatal Opioid Exposure. Cells. 2024;13: pubmed publisher
Pfeffer T, Wetzel C, Kirschner P, Bartosova M, Poth T, Schwab C, et al. Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet. Antioxidants (Basel). 2023;12: pubmed publisher
Samsonraj R, Law S, Chandra A, Pignolo R. An unbiased proteomics approach to identify the senescence-associated secretory phenotype of human bone marrow-derived mesenchymal stem cells. Bone Rep. 2023;18:101674 pubmed publisher
Soundararajan A, Wang T, Ghag S, Kang M, Pattabiraman P. Novel insight into the role of clusterin on intraocular pressure regulation by modifying actin polymerization and extracellular matrix remodeling in the trabecular meshwork. J Cell Physiol. 2022;237:3012-3029 pubmed publisher
Annarapu G, Nolfi Donegan D, Reynolds M, Wang Y, Kohut L, Zuckerbraun B, et al. Heme stimulates platelet mitochondrial oxidant production to induce targeted granule secretion. Redox Biol. 2021;48:102205 pubmed publisher
Vanhoutte D, Schips T, Vo A, Grimes K, Baldwin T, Brody M, et al. Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy. Nat Commun. 2021;12:3928 pubmed publisher
Bhattacharya A, Janal M, Veeramachaneni R, Dolgalev I, Dubeykovskaya Z, Tu N, et al. Oncogenes overexpressed in metastatic oral cancers from patients with pain: potential pain mediators released in exosomes. Sci Rep. 2020;10:14724 pubmed publisher
Mouton A, Ma Y, Rivera Gonzalez O, Daseke M, Flynn E, Freeman T, et al. Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis. Basic Res Cardiol. 2019;114:6 pubmed publisher
Salunkhe V, De Cuyper I, Papadopoulos P, van der Meer P, Daal B, Villa Fajardo M, et al. A comprehensive proteomics study on platelet concentrates: Platelet proteome, storage time and Mirasol pathogen reduction technology. Platelets. 2019;30:368-379 pubmed publisher
Miao X, Rahman M, Jiang L, Min Y, Tan S, Xie H, et al. Thrombin-reduced miR-27b attenuates platelet angiogenic activities in vitro via enhancing platelet synthesis of anti-angiogenic thrombospondin-1. J Thromb Haemost. 2018;16:791-801 pubmed publisher
Koh S, Chen W, Dejneka N, Harris I, Lu B, Girman S, et al. Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity. J Neurosci. 2018;38:2923-2943 pubmed publisher
product information
master code :
AF3074
SKU :
AF3074
product name :
Human Thrombospondin-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Thrombospondin-1 Antibody from R&D Systems is a goat polyclonal antibody to Thrombospondin-1. This antibody reacts with human,mouse,rat. The Human Thrombospondin-1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation,Dot Blot,Immunohistochemistry-Paraffin,Simple Western.
target :
Thrombospondin-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Thrombospondin-1, Asn19-Pro1170, Accession # CAA32889
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human Thrombospondin-1 in direct ELISAs and Western blots.
gene symbol :
THBS1
top caption :
Detection of Human Thrombospondin-1 antibody by Western Blot.
accessionNumbers :
CAA32889
applications :
Western Blot,Immunohistochemistry,Immunoprecipitation,Dot Blot,Immunohistochemistry-Paraffin,Simple Western
USD :
499 USD
alt names :
THBS, THBS1, THBS-1, thrombospondin 1, Thrombospondin1, thrombospondin-1p180, TSP-1, TSP1thrombospondin-1, TSPTSP-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.