product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse FGF-21 Antibody
catalog :
AF3057
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, neutralization
more info or order :
citations: 7
Reference
Sun J, Du L, Shi X, Zhang Y, Liu Y, Wang Y, et al. An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction. Sci Adv. 2023;9:eade4110 pubmed publisher
Lee B, An H, Kim D, Lee M, Jeong H, Chung K, et al. SMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice. Exp Mol Med. 2022;54:2036-2046 pubmed publisher
Kim J, Lee S, Lee M. Suppressive Effect of Autocrine FGF21 on Autophagy-Deficient Hepatic Tumorigenesis. Front Oncol. 2022;12:832804 pubmed publisher
Reilly S, Abu Odeh M, Ameka M, DeLuca J, Naber M, Dadpey B, et al. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. J Clin Invest. 2021;131: pubmed publisher
Timper K, Del Río Martín A, Cremer A, Bremser S, Alber J, Giavalisco P, et al. GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function. Cell Metab. 2020;31:1189-1205.e13 pubmed publisher
Turpin Nolan S, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, et al. CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019;26:1-10.e7 pubmed publisher
Zhang J, Gupte J, Gong Y, Weiszmann J, Zhang Y, Lee K, et al. Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action. EBioMedicine. 2017;15:173-183 pubmed publisher
product information
master code :
AF3057
SKU :
AF3057
product name :
Mouse FGF-21 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse FGF-21 Antibody from R&D Systems is a goat polyclonal antibody to FGF-21. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse FGF-21 Antibody has been validated for the following applications: Western Blot,ELISA Development (Capture),Neutralization.
target :
FGF-21
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse FGF-21, Tyr30-Ser210, Accession # Q9JJN1
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse FGF-21 in direct ELISAs and Western blots. In these formats, approximately 15% cross-reactivity with recombinant human (rh) FGF-21 is observed and less than 1% cross-reactivity with rhFGF-19 and rhFGF-23 is observed.
gene symbol :
FGF21
top caption :
Detection of Mouse FGF-21 antibody by Western Blot.
accessionNumbers :
Q9JJN1
applications :
ELISA Development (Capture),Western Blot,Neutralization
USD :
509 USD
alt names :
FGF21, FGF-21, fibroblast growth factor 21
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.