Human IL-32 Antibody | R&D Systems AF3040 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-32 Antibody

catalog :

AF3040

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Reference
Kastnes M, Aass K, Bouma S, xc5 rseth C, Zahoor M, Yurchenko M, et al. The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes. Front Oncol. 2023;13:1197542 pubmed publisher
Aass K, Tryggestad S, Mjelle R, Kastnes M, Nedal T, Misund K, et al. IL-32 is induced by activation of toll-like receptors in multiple myeloma cells. Front Immunol. 2023;14:1107844 pubmed publisher
Aass K, Mjelle R, Kastnes M, Tryggestad S, van den Brink L, Aass Roseth I, et al. Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells. iScience. 2022;25:103605 pubmed publisher
Dos Santos J, Barroso de Figueiredo A, Teodoro Silva M, Cirovic B, de Bree L, Damen M, et al. β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32. Cell Rep. 2019;28:2659-2672.e6 pubmed publisher
Sloot Y, Rabold K, Ulas T, de Graaf D, Heinhuis B, Händler K, et al. Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration. Cell Oncol (Dordr). 2019;: pubmed publisher
Damen M, Schraa K, Tweehuysen L, den Broeder A, Netea M, Popa C, et al. Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients. Sci Rep. 2018;8:14050 pubmed publisher
Palstra R, De Crignis E, Röling M, van Staveren T, Kan T, van Ijcken W, et al. Allele-specific long-distance regulation dictates IL-32 isoform switching and mediates susceptibility to HIV-1. Sci Adv. 2018;4:e1701729 pubmed publisher

product information

master code :

AF3040

SKU :

AF3040

product name :

Human IL-32 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human IL-32 Antibody from R&D Systems is a goat polyclonal antibody to IL-32. This antibody reacts with human,transgenic mouse. The Human IL-32 Antibody has been validated for the following applications: Western Blot,Electrochemiluminescent Assay,ELISA Development,Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

IL-32

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human IL-32 alpha , Cys2-Lys131, Accession # NP_001012651

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Transgenic Mouse

specificity :

Detects human IL-32 in direct ELISAs and Western blots.

gene symbol :

IL32

accessionNumbers :

NP_001012651

applications :

Electrochemiluminescent Assay,ELISA Development,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

499 USD

alt names :

IL32, IL-32, IL-32alpha, IL-32beta, interleukin 32, interleukin-32, interleukin-32 theta, natural killer cell transcript 4, Natural killer cells protein 4, NK4, NK4IL-32delta, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, TAIFIL-32gamma, Tumor necrosis factor alpha-inducing factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage