Human TGF┐▀ RI/ALK-5 Antibody | R&D Systems AF3025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TGF┐▀ RI/ALK-5 Antibody

catalog :

AF3025

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, bovine

application :

western blot, ELISA, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5a	Nam B, Park H, Lee Y, Oh Y, Park J, Kim S, et al. TGFβ1 Suppressed Matrix Mineralization of Osteoblasts Differentiation by Regulating SMURF1-C/EBPβ-DKK1 Axis. Int J Mol Sci. 2020;21: pubmed publisher
	Windus L, Matigian N, Avery V. Induction of Reactive Bone Stromal Fibroblasts in 3D Models of Prostate Cancer Bone Metastases. Biology (Basel). 2023;12: pubmed publisher
	Zhang H, Li B, Huang Q, L xf3 pez Gir xe1 ldez F, Tanaka Y, Lin Q, et al. Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas. Nat Commun. 2022;13:7637 pubmed publisher
	Cheng W, Li H, Xi S, Zhang X, Zhu Y, Le Xing -, et al. Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021;12:7142 pubmed publisher
	Li C, Meng X, Liu S, Li W, Zhang X, Zhou J, et al. Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells. Development. 2020;147: pubmed publisher
	Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
	Wang B, Xu X, Yang Z, Zhang L, Liu Y, Ma A, et al. POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1. EBioMedicine. 2019;41:320-332 pubmed publisher
	Chen Y, Wang D, Wu Y, Su D, Zhou T, Gai R, et al. MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. Br J Cancer. 2017;117:1192-1201 pubmed publisher

product information

master code :

AF3025

SKU :

AF3025

product name :

Human TGF┐▀ RI/ALK-5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TGF¿ß RI/ALK-5 Antibody from R&D Systems is a goat polyclonal antibody to TGF-beta RI/ALK-5. This antibody reacts with bovine,human,mouse. The Human TGF¿ß RI/ALK-5 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,ELISA.

target :

TGF-beta RI/ALK-5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TGF┐▀ RI/ALK-5, Leu34-Glu125, Accession # P36897

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bovine,Human,Mouse

specificity :

Detects human TGF┐▀ RI/ALK-5 in direct ELISAs and Western blots. In direct ELISAs, less than 25% cross-reactivity with recombinant mouse TGF┐▀ RI is observed.

gene symbol :

TGFBR1

top caption :

Detection of Human TGF-ss RI/ALK-5 antibody by Western Blot.

accessionNumbers :

P36897

applications :

Western Blot,Immunocytochemistry,ELISA

USD :

489 USD

alt names :

AAT5, activin A receptor type II-like kinase, 53kD, activin A receptor type II-like kinase, 53kDa, Activin receptor-like kinase 5, ACVRLK4, ALK-5, ALK-5ALK5, EC 2.7.11, EC 2.7.11.30, LDS1A, LDS2A, Serine/threonine-protein kinase receptor R4, SKR4, TbetaR-I, TGFB1R1, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFbetaRI, TGFBR1, TGF-bRI, TGFR-1, transforming growth factor beta receptor I, transforming growth factor, beta receptor 1, transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD), Transforming growth factor-beta receptor type I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage