Human Norrin Antibody | R&D Systems AF3014 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Norrin Antibody

catalog :

AF3014

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 3

Reference
Liu M, Dai E, Yang M, Li S, Fan L, Liu Y, et al. Investigating the Impact of Dimer Interface Mutations on Norrin's Secretion and Norrin/β-Catenin Pathway Activation. Invest Ophthalmol Vis Sci. 2024;65:31 pubmed publisher
Pauzuolyte V, Patel A, Wawrzynski J, Ingham N, Leong Y, Karda R, et al. Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease. EMBO Mol Med. 2023;15:e17393 pubmed publisher
El Sehemy A, Selvadurai H, Ortín Martínez A, Pokrajac N, Mamatjan Y, Tachibana N, et al. Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt. J Clin Invest. 2020;130:3069-3086 pubmed publisher

product information

master code :

AF3014

SKU :

AF3014

product name :

Human Norrin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Norrin Antibody from R&D Systems is a goat polyclonal antibody to Norrin/NDP. This antibody reacts with human. The Human Norrin Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Blockade of Receptor-ligand Interaction.

target :

Norrin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human Norrin, Lys25-Ser133, Accession # Q00604

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human Norrin in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Norrin is observed.

gene symbol :

NDP

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q00604

applications :

Western Blot,Neutralization,Immunohistochemistry,Blockade of Receptor-ligand Interaction

USD :

469 USD

alt names :

EVR2, exudative vitreoretinopathy 2 (X-linked), FEVR, ND, NDP, Norrie disease (pseudoglioma), Norrie disease protein, norrin, X-linked exudative vitreoretinopathy 2 protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage