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company name :
R&D Systems
product type :
antibody
product name :
Mouse Serum Amyloid A1/A2 Antibody
catalog :
AF2948
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 24
Reference
Holcomb M, Marshall A, Flinn H, Lozano M, Soriano S, Gomez Pinilla F, et al. Probiotic treatment causes sex-specific neuroprotection after traumatic brain injury in mice. Res Sq. 2024;: pubmed publisher
He M, Liu Y, Chen S, Deng H, Feng C, Qiao S, et al. Serum amyloid A promotes glycolysis of neutrophils during PD-1 blockade resistance in hepatocellular carcinoma. Nat Commun. 2024;15:1754 pubmed publisher
Yu J, Zhu H, Taheri S, Lee J, Diamond D, Kirstein C, et al. Serum amyloid A-dependent inflammasome activation and acute injury in a mouse model of experimental stroke. Res Sq. 2023;: pubmed publisher
He C, Konishi R, Harata A, Nakamura Y, Mizuno R, Yoda M, et al. Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model. Front Immunol. 2023;14:1097788 pubmed publisher
Vaisar T, Wang S, Omer M, Irwin A, Storey C, Tang C, et al. 10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice. J Lipid Res. 2022;63:100241 pubmed publisher
Soriano S, Curry K, Wang Q, Chow E, Treangen T, Villapol S. Fecal Microbiota Transplantation Derived from Alzheimer's Disease Mice Worsens Brain Trauma Outcomes in Wild-Type Controls. Int J Mol Sci. 2022;23: pubmed publisher
Wakai M, Hayashi R, Ueno Y, Onishi K, Takasago T, Uchida T, et al. Promoting mechanism of serum amyloid a family expression in mouse intestinal epithelial cells. PLoS ONE. 2022;17:e0264836 pubmed publisher
Song Y, Hu S, Zhang J, Zhu L, Zhao X, Chen Q, et al. Fractionated Irradiation of Right Thorax Induces Abscopal Damage on Bone Marrow Cells via TNF-α and SAA. Int J Mol Sci. 2021;22: pubmed publisher
Farré Alins V, Palomino Antolin A, Narros Fernández P, López Rodríguez A, Decouty Pérez C, Muñoz Montero A, et al. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients. Biomedicines. 2021;9: pubmed publisher
Massart I, Paulissen G, Loumaye A, Lause P, Pötgens S, Thibaut M, et al. Marked Increased Production of Acute Phase Reactants by Skeletal Muscle during Cancer Cachexia. Cancers (Basel). 2020;12: pubmed publisher
Lim S, Dunlap K, Rosa Caldwell M, Haynie W, Jansen L, Washington T, et al. Comparative plasma proteomics in muscle atrophy during cancer-cachexia and disuse: The search for atrokines. Physiol Rep. 2020;8:e14608 pubmed publisher
Han C, Kang I, Omer M, Wang S, Wietecha T, Wight T, et al. Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties. JCI Insight. 2020;5: pubmed publisher
Chait A, den Hartigh L, Wang S, Goodspeed L, Babenko I, Altemeier W, et al. Presence of serum amyloid A3 in mouse plasma is dependent on the nature and extent of the inflammatory stimulus. Sci Rep. 2020;10:10397 pubmed publisher
Gan X, Wang W, Lu J, Ling L, Zhou Q, Zhang H, et al. De novo Synthesis of SAA1 in the Placenta Participates in Parturition. Front Immunol. 2020;11:1038 pubmed publisher
Smole U, Gour N, Phelan J, Hofer G, Köhler C, Kratzer B, et al. Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity. Nat Immunol. 2020;21:756-765 pubmed publisher
Soriano S, Moffet B, Wicker E, Villapol S. Serum Amyloid A is Expressed in the Brain After Traumatic Brain Injury in a Sex-Dependent Manner. Cell Mol Neurobiol. 2020;40:1199-1211 pubmed publisher
Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al. Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. Cell. 2020;180:79-91.e16 pubmed publisher
Zheng H, Li H, Zhang J, Fan H, Jia L, Ma W, et al. Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection. J Biol Chem. 2020;295:2570-2581 pubmed publisher
Li Y, Xu Y, Jadhav K, Zhu Y, Yin L, Zhang Y. Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis. Arterioscler Thromb Vasc Biol. 2019;39:1574-1587 pubmed publisher
Wicker E, Benton L, George K, Furlow W, Villapol S. Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury. Biomed Res Int. 2019;2019:5967816 pubmed publisher
Wang H, Blackall M, Sominsky L, Spencer S, Vlahos R, Churchill M, et al. Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production. J Neuroinflammation. 2018;15:200 pubmed publisher
Hinrichs B, Matthews J, Siuda D, O Leary M, Wolfarth A, Saeedi B, et al. Serum Amyloid A1 Is an Epithelial Prorestitutive Factor. Am J Pathol. 2018;188:937-949 pubmed publisher
Li X, Lyu Y, Shen J, Mu Y, Qiang L, Liu L, et al. Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci. Lab Invest. 2018;98:512-524 pubmed publisher
Zhang Y, Wei Y, Jiang B, Chen L, Bai H, Zhu X, et al. Scavenger Receptor A1 Prevents Metastasis of Non-Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1. Cancer Res. 2017;77:1586-1598 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2948
SKU :
AF2948
product name :
Mouse Serum Amyloid A1/A2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Serum Amyloid A1/A2 Antibody from R&D Systems is a goat polyclonal antibody to Serum Amyloid A1/A2. This antibody reacts with human,mouse. The Mouse Serum Amyloid A1/A2 Antibody has been validated for the following applications: Western Blot,In vivo assay,ELISA Development,Neutralization,Cell Culture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Simple Western.
target :
Serum Amyloid A1/A2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 50 ug/mL, ELISA, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse Serum Amyloid A1, Gly20-Tyr122, Accession # P05366
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects mouse Serum Amyloid A1/SAA1 and mouse Serum Amyloid A2/SAA2 in direct ELISAs and Western blots.
gene symbol :
SAA1
top caption :
Detection of Mouse Serum Amyloid A1/A2 antibody by Western Blot.
accessionNumbers :
P05366
applications :
ELISA,Simple Western,ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,In vivo assay,Neutralization,Immunocytochemistry,Cell Culture
USD :
519 USD
alt names :
PIG4, PIG4;SAA;SAA1;SAA2;Serum amyloid A-1 protein;Serum amyloid A-2 protein;TP53I4, SAA1, SAA2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.