Human NRL Antibody | R&D Systems AF2945 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NRL Antibody

catalog :

AF2945

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry knockout validation

more info or order :

R&D Systems product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; human; 1:100; fig 2i	Cuevas E, Holder D, Alshehri A, Tr xe9 guier J, Lakowski J, Sowden J. NRL-/- gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors. Stem Cells. 2021;39:414-428 pubmed publisher
immunocytochemistry; human; fig 2b	Salas A, Duarri A, Fontrodona L, Ram xed rez D, Badia A, Isla Magran xe9 H, et al. Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration. Mol Ther Methods Clin Dev. 2021;20:688-702 pubmed publisher
	Corso D xed az X, Liang X, Preston K, Tegshee B, English M, Nellissery J, et al. Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors. bioRxiv. 2025;: pubmed publisher
	Bohrer L, Stone N, Mullin N, Voigt A, Anfinson K, Fick J, et al. Automating iPSC generation to enable autologous photoreceptor cell replacement therapy. J Transl Med. 2023;21:161 pubmed publisher
	Le N, Appel H, Pannullo N, Hoang T, Blackshaw S. Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina. Front Cell Dev Biol. 2022;10:914386 pubmed publisher
	Han I, Bohrer L, Gibson Corley K, Wiley L, Shrestha A, Harman B, et al. Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats. Cell Transplant. 2022;31:9636897221104451 pubmed publisher
	Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Yada Y, et al. One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors. iScience. 2022;25:103987 pubmed publisher
	Yamasaki S, Kuwahara A, Kishino A, Kimura T, Takahashi M, Mandai M. Addition of Chk1 inhibitor and BMP4 cooperatively promotes retinal tissue formation in self-organizing human pluripotent stem cell differentiation culture. Regen Ther. 2022;19:24-34 pubmed publisher
	Afanasyeva T, Corral Serrano J, Garanto A, Roepman R, Cheetham M, Collin R. A look into retinal organoids: methods, analytical techniques, and applications. Cell Mol Life Sci. 2021;78:6505-6532 pubmed publisher
	Cowan C, Renner M, De Gennaro M, Gross Scherf B, Goldblum D, Hou Y, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182:1623-1640.e34 pubmed publisher
	Lu Y, Shiau F, Yi W, Lu S, Wu Q, Pearson J, et al. Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development. Dev Cell. 2020;53:473-491.e9 pubmed publisher
	Gao M, Lei X, Han F, He K, Jin S, Zhang Y, et al. Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa. Front Cell Dev Biol. 2020;8:128 pubmed publisher
	Kuwahara A, Yamasaki S, Mandai M, Watari K, Matsushita K, Fujiwara M, et al. Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue. Sci Rep. 2019;9:18936 pubmed publisher
	Gonzalez Cordero A, Kruczek K, Naeem A, Fernando M, Kloc M, Ribeiro J, et al. Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors. Stem Cell Reports. 2017;9:820-837 pubmed publisher

product information

master code :

AF2945

SKU :

AF2945

product name :

Human NRL Antibody

unit size :

100 ug (also 25 ug)

description :

The Human NRL Antibody from R&D Systems is a goat polyclonal antibody to NRL. This antibody reacts with human,mouse,xenograft. The Human NRL Antibody has been validated for the following applications: Immunohistochemistry,Functional Assay,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

NRL

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human NRL, Met1-Leu237, Accession # P54845

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Xenograft

specificity :

Detects human NRL in direct ELISAs and Western blots.

gene symbol :

NRL

accessionNumbers :

P54845

applications :

Immunohistochemistry,Functional Assay,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

499 USD

alt names :

D14S46Eneural retina-specific leucine zipper protein, neural retina leucine zipper, NRL-MAF, RP27, RP27neural retinal-specific leucine zipper

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage