Human PLZF Antibody | R&D Systems AF2944 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human PLZF Antibody

catalog :

AF2944

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 27

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 2k	Ma L, Xie D, Luo M, Lin X, Nie H, Chen J, et al. Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis. Sci Adv. 2022;8:eabn1606 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 7d	Smith K, Dinh D, Akison L, Nicholls M, Dunning K, Morimoto A, et al. Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation. Cells. 2022;11: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1i western blot; mouse; 1:1000; loading ...; fig 5b	Dong F, Chen M, Jiang L, Shen Z, Ma L, Han C, et al. PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications. Front Cell Dev Biol. 2021;9:673258 pubmed publisher
	Wei X, Zhang Z, Gu Y, Zhang R, Huang J, Li F, et al. Inter- and trans-generational impacts of real-world PM2.5 exposure on male-specific primary hypogonadism. Cell Discov. 2024;10:44 pubmed publisher
	Lei W, Li Y, Du Z, Su R, Meng T, Ning Y, et al. SRSF1-mediated alternative splicing is required for spermatogenesis. Int J Biol Sci. 2023;19:4883-4897 pubmed publisher
	Yamanaka S, Furihata H, Yanagihara Y, Taya A, Nagasaka T, Usui M, et al. Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation. Nat Commun. 2023;14:4683 pubmed publisher
	Liu W, Lu X, Zhao Z, Su R, Li Q, Xue Y, et al. SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing. elife. 2022;11: pubmed publisher
	Li M, Chen Y, Ou J, Huang J, Zhang X. PDCL2 is essential for spermiogenesis and male fertility in mice. Cell Death Discov. 2022;8:419 pubmed publisher
	Peart N, Johnson T, Lee S, Sears M, Yang F, Quesnel Valli xe8 res M, et al. The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice. PLoS Genet. 2022;18:e1010416 pubmed publisher
	Burda J, O Shea T, Ao Y, Suresh K, Wang S, Bernstein A, et al. Divergent transcriptional regulation of astrocyte reactivity across disorders. Nature. 2022;606:557-564 pubmed publisher
	Dang H, Martin Villalba A, Schiebel E. Centrosome linker protein C-Nap1 maintains stem cells in mouse testes. EMBO Rep. 2022;23:e53805 pubmed publisher
	Barroca V, Racine C, Pays L, Fouchet P, Coureuil M, Allemand I. The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice. Stem Cell Res. 2022;60:102723 pubmed publisher
	Yamanaka S, Horiuchi Y, Matsuoka S, Kido K, Nishino K, Maeno M, et al. A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues. Nat Commun. 2022;13:183 pubmed publisher
	Liu W, Zhang L, Gao A, Khawar M, Gao F, Li W. Food-Derived High Arginine Peptides Promote Spermatogenesis Recovery in Busulfan Treated Mice. Front Cell Dev Biol. 2021;9:791471 pubmed publisher
	Lei W, Li Y, Meng T, Ning Y, Sun S, Zhang C, et al. Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis. Cell Death Dis. 2021;12:883 pubmed publisher
	Suzuki S, McCarrey J, Hermann B. Differential RA responsiveness among subsets of mouse late progenitor spermatogonia. Reproduction. 2021;161:645-655 pubmed publisher
	Yamanaka S, Murai H, Saito D, Abe G, Tokunaga E, Iwasaki T, et al. Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF. EMBO J. 2021;40:e105375 pubmed publisher
	Mikedis M, Fan Y, Nicholls P, Endo T, Jackson E, Cobb S, et al. DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors. elife. 2020;9: pubmed publisher
	Wang M, Yu L, Wang S, Yang F, Wang M, Li L, et al. LIN28A binds to meiotic gene transcripts and modulates their translation in male germ cells. J Cell Sci. 2020;133: pubmed publisher
	Legrand J, Chan A, La H, Rossello F, Ankö M, Fuller Pace F, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278 pubmed publisher
	Fu K, Tian S, Tan H, Wang C, Wang H, Wang M, et al. Biological and RNA regulatory function of MOV10 in mammalian germ cells. BMC Biol. 2019;17:39 pubmed publisher
	Tang R, Fan L. PLZFposc-KITpos-delineated A1-A4-differentiating spermatogonia by subset and stage detection upon Bouin fixation. Asian J Androl. 2019;21:309-318 pubmed publisher
	Bai S, Fu K, Yin H, Cui Y, Yue Q, Li W, et al. Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. Development. 2018;145: pubmed publisher
	Jamin S, Petit F, Kervarrec C, Smagulova F, Illner D, Scherthan H, et al. EXOSC10/Rrp6 is post-translationally regulated in male germ cells and controls the onset of spermatogenesis. Sci Rep. 2017;7:15065 pubmed publisher
	Gassei K, Sheng Y, Fayomi A, Mital P, Sukhwani M, Lin C, et al. DDX4-EGFP transgenic rat model for the study of germline development and spermatogenesis. Biol Reprod. 2017;96:707-719 pubmed publisher
	Beyaz S, Kim J, Pinello L, Xifaras M, Hu Y, Huang J, et al. The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nat Immunol. 2017;18:184-195 pubmed publisher
	Mao A, Constantinides M, Mathew R, Zuo Z, Chen X, Weirauch M, et al. Multiple layers of transcriptional regulation by PLZF in NKT-cell development. Proc Natl Acad Sci U S A. 2016;113:7602-7 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2944

SKU :

AF2944

product name :

Human PLZF Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human PLZF Antibody from R&D Systems is a goat polyclonal antibody to PLZF. This antibody reacts with human,mouse,rat,transgenic mouse. The Human PLZF Antibody has been validated for the following applications: Immunohistochemistry,IHC-F,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Simple Western.

target :

PLZF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human PLZF, Met1-Gln254, Accession # Q05516

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects human PLZF in direct ELISAs and Western blots.

gene symbol :

ZBTB16

top caption :

Detection of Human PLZF antibody by Western Blot.

accessionNumbers :

Q05516

applications :

Simple Western,IHC-F,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

519 USD

alt names :

PLZFzinc finger and BTB domain-containing protein 16, ZBTB16, zinc finger and BTB domain containing 16, Zinc finger protein 145, zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia), Zinc finger protein PLZF, ZNF145, ZNF145Promyelocytic leukemia zinc finger protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage