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company name :
R&D Systems
product type :
antibody
product name :
Mouse SPARC-like 1/SPARCL1 Antibody
catalog :
AF2836
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 7c
Osokine I, Siewiera J, Rideaux D, Ma S, Tsukui T, Erlebacher A. Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface. Cell Rep. 2022;38:110329 pubmed publisher
Le A, Fu M, Kumar R, Zacharias G, Garcia A. Astrocyte modulation of synaptic plasticity mediated by activity-dependent Sonic hedgehog signaling. bioRxiv. 2024;: pubmed publisher
Niebergall E, Weekley D, Mazur A, Olszewski N, DeSchepper K, Radant N, et al. Abnormal Morphology and Synaptogenic Signaling in Astrocytes Following Prenatal Opioid Exposure. Cells. 2024;13: pubmed publisher
Alfonso A, Pomerleau V, Nicol xe1 s V, Raisch J, Jurkovic C, Boisvert F, et al. Comprehensive Profiling of Early Neoplastic Gastric Microenvironment Modifications and Biodynamics in Impaired BMP-Signaling FoxL1+-Telocytes. Biomedicines. 2022;11: pubmed publisher
Wang Y, Zhang S, Lan Z, Doan V, Kim B, Liu S, et al. SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice. Cell Rep. 2022;41:111842 pubmed publisher
Shelkar G, Gandhi P, Liu J, Dravid S. Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens. Sci Adv. 2022;8:eabo6574 pubmed publisher
Wu X, Sosunov A, Lado W, Teoh J, Ham A, Li H, et al. Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex. Cell Rep. 2022;40:111085 pubmed publisher
Taketomi T, Yasuda T, Morita R, Kim J, Shigeta Y, Eroglu C, et al. Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability. Sci Rep. 2022;12:11891 pubmed publisher
Udagawa T, Atkinson P, Milon B, Abitbol J, Song Y, Sperber M, et al. Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration. PLoS Biol. 2021;19:e3001445 pubmed publisher
Jan T, Eltawil Y, Ling A, Chen L, Ellwanger D, Heller S, et al. Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics. Cell Rep. 2021;36:109358 pubmed publisher
Kubota M, Scheibinger M, Jan T, Heller S. Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea. Cell Rep. 2021;34:108646 pubmed publisher
Regensburger D, Tenkerian C, P xfc rzer V, Schmid B, Wohlfahrt T, Stolzer I, et al. Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021;27:1491-1502 pubmed publisher
Yu L, Zheng Y, Liu B, Kang M, Millar J, Rhee D. Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility. PLoS ONE. 2020;15:e0241294 pubmed publisher
Klingler A, Regensburger D, Tenkerian C, Britzen Laurent N, Hartmann A, Sturzl M, et al. Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues. PLoS ONE. 2020;15:e0233422 pubmed publisher
product information
master code :
AF2836
SKU :
AF2836
product name :
Mouse SPARC-like 1/SPARCL1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse SPARC-like 1/SPARCL1 Antibody from R&D Systems is a goat polyclonal antibody to SPARC-like 1/SPARCL1. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse SPARC-like 1/SPARCL1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry,RNAscope compatible.
target :
SPARC-like 1/SPARCL1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse SPARC-like 1/SPARCL1 (R D Systems, Catalog # 4547-SL), Ile17-Phe650, Accession # P70663
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse SPARC-like 1 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human SPARC-like 1 is observed and less than 1% cross-reactivity with recombinant mouse SPARC is observed.
gene symbol :
SPARCL1
top caption :
Detection of Mouse SPARC-like 1/SPARCL1 by Immunocytochemistry/Immunofluorescence
accessionNumbers :
P70663
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry,RNAscope compatible
USD :
499 USD
alt names :
hevin, High endothelial venule protein, MAST 9, MAST9, PIG33, proliferation-inducing protein 33, SC1, SPARC like 1, SPARCL1, SPARC-like 1 (hevin), SPARC-like 1 (mast9, hevin), SPARC-like protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.