Mouse MFG-E8 Antibody | R&D Systems AF2805 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse MFG-E8 Antibody

catalog :

AF2805

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse, bovine

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 18

Reference
Sokolova D, Ghansah S, Puletti F, Georgiades T, De Schepper S, Zheng Y, et al. Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models. bioRxiv. 2024;: pubmed publisher
Itoh Y, Sahni V, Shnider S, Mckee H, Macklis J. Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations. Cell Rep. 2023;42:112182 pubmed publisher
Han D, Lu D, Huang S, Pang J, Wu Y, Hu J, et al. Small extracellular vesicles from Ptpn1-deficient macrophages alleviate intestinal inflammation by reprogramming macrophage polarization via lactadherin enrichment. Redox Biol. 2022;58:102558 pubmed publisher
Wagner J, Degenhardt K, Veit M, Louros N, Konstantoulea K, Skodras A, et al. Medin co-aggregates with vascular amyloid-β in Alzheimer's disease. Nature. 2022;612:123-131 pubmed publisher
Ni L, Liu L, Zhu W, Telljohann R, Zhang J, Monticone R, et al. Inflammatory Role of Milk Fat Globule-Epidermal Growth Factor VIII in Age-Associated Arterial Remodeling. J Am Heart Assoc. 2022;11:e022574 pubmed publisher
Han G, Kim H, Kim D, Ahn Y, Kim J, Jang Y, et al. The Potential of Bovine Colostrum-Derived Exosomes to Repair Aged and Damaged Skin Cells. Pharmaceutics. 2022;14: pubmed publisher
Marazuela P, Solé M, Bonaterra Pastra A, Pizarro J, Camacho J, Martínez Sáez E, et al. MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy. Acta Neuropathol Commun. 2021;9:154 pubmed publisher
Lu Y, Liu L, Pan J, Luo B, Zeng H, Shao Y, et al. MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway. Cell Death Dis. 2021;12:533 pubmed publisher
Bu H, Subramanian S, Geng H, Wang X, Liu F, Chou P, et al. MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice. Cells. 2021;10: pubmed publisher
Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh A, Delpech J, et al. Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. Nat Commun. 2020;11:6133 pubmed publisher
Egaña Gorroño L, Chinnasamy P, Casimiro I, Almonte V, Parikh D, Oliveira Paula G, et al. Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019;289:184-194 pubmed publisher
Eguchi S, Takefuji M, Sakaguchi T, Ishihama S, Mori Y, Tsuda T, et al. Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction. J Biol Chem. 2019;294:11665-11674 pubmed publisher
Brelstaff J, Tolkovsky A, Ghetti B, Goedert M, Spillantini M. Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia. Cell Rep. 2018;24:1939-1948.e4 pubmed publisher
Reardon C, Lingaraju A, Schoenfelt K, Zhou G, Cui C, Jacobs El H, et al. Obesity and Insulin Resistance Promote Atherosclerosis through an IFN?-Regulated Macrophage Protein Network. Cell Rep. 2018;23:3021-3030 pubmed publisher
Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
Wang J, Forterre A, Zhao J, Frimannsson D, Delcayre A, Antes T, et al. Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation. Mol Cancer Ther. 2018;17:1133-1142 pubmed publisher
Yuzwa S, Borrett M, Innes B, Voronova A, Ketela T, Kaplan D, et al. Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling. Cell Rep. 2017;21:3970-3986 pubmed publisher
Wang X, Hao L, Bu H, Scott A, Tian K, Liu F, et al. Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8 gene expression and restores enterocyte migration in lipopolysaccharide-induced septic mice. Sci Rep. 2016;6:31687 pubmed publisher

product information

master code :

AF2805

SKU :

AF2805

product name :

Mouse MFG-E8 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse MFG-E8 Antibody from R&D Systems is a goat polyclonal antibody to MFG-E8. This antibody reacts with bovine,mouse,transgenic mouse. The Mouse MFG-E8 Antibody has been validated for the following applications: Western Blot,Immunoprecipitation,Immunohistochemistry,In vivo assay,Simple Western.

target :

MFG-E8

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse MFG-E8 (R D Systems, Catalog # 2805-MF), Ala23-Cys463, Accession # P21956

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bovine,Mouse,Transgenic Mouse

specificity :

Detects mouse MFG-E8 in direct ELISAs and Western blots. In these formats, less than 2% cross-reactivity with recombinant human MFG-E8 is observed.

gene symbol :

MFGE8

top caption :

Detection of Mouse MFG-E8 antibody by Western Blot.

accessionNumbers :

P21956

applications :

Western Blot,Immunoprecipitation,Immunohistochemistry,In vivo assay,Simple Western

USD :

499 USD

alt names :

BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, Lactahedrin, Medin, MFG1, MFGE8, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage