Mouse pIgR Antibody | R&D Systems AF2800 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse pIgR Antibody

catalog :

AF2800

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 12

Reference
Donald K, Serapio Palacios A, Gerbec Z, Bozorgmehr T, Holani R, Cruz A, et al. Secretory IgA in breast milk protects against asthma through modulation of the gut microbiota. Cell Rep. 2024;43:114835 pubmed publisher
Kinashi Y, Tanaka K, Kimura S, Hirota M, Komiyama S, Shindo T, et al. Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice. EBioMedicine. 2024;106:105256 pubmed publisher
Hu S, Liu S, Bian Y, Poddar M, Singh S, Cao C, et al. Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b. Cell Rep Med. 2022;3:100754 pubmed publisher
Zeng B, Wang H, Luo J, Xie M, Zhao Z, Chen X, et al. Porcine Milk-Derived Small Extracellular Vesicles Promote Intestinal Immunoglobulin Production through pIgR. Animals (Basel). 2021;11: pubmed publisher
Collin A, Lecocq M, Noel S, Detry B, Carlier F, Aboubakar Nana F, et al. Lung immunoglobulin A immunity dysregulation in cystic fibrosis. EBioMedicine. 2020;60:102974 pubmed publisher
Zeng B, Wang D, Wang H, Chen T, Luo J, Xi Q, et al. Dietary Soy Protein Isolate Attenuates Intestinal Immunoglobulin and Mucin Expression in Young Mice Compared with Casein. Nutrients. 2020;12: pubmed publisher
Yang C, Mogno I, Contijoch E, Borgerding J, Aggarwala V, Li Z, et al. Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation. Cell Host Microbe. 2020;27:467-475.e6 pubmed publisher
Noval Rivas M, Wakita D, Franklin M, Carvalho T, Abolhesn A, Gomez A, et al. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity. 2019;51:508-521.e6 pubmed publisher
Bornstein C, Nevo S, Giladi A, Kadouri N, Pouzolles M, Gerbe F, et al. Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells. Nature. 2018;559:622-626 pubmed publisher
Basic M, Buettner M, Keubler L, Smoczek A, Bruesch I, Buchheister S, et al. Loss of CD14 leads to disturbed epithelial-B cell crosstalk and impairment of the intestinal barrier after E. coli Nissle monoassociation. Sci Rep. 2018;8:719 pubmed publisher
Azzam K, Madenspacher J, Cain D, Lai L, Gowdy K, Rai P, et al. Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. JCI Insight. 2017;2: pubmed publisher
Nakanishi K, Morikane S, Ichikawa S, Kurohane K, Niwa Y, Akimoto Y, et al. Protection of Human Colon Cells from Shiga Toxin by Plant-based Recombinant Secretory IgA. Sci Rep. 2017;7:45843 pubmed publisher

product information

master code :

AF2800

SKU :

AF2800

product name :

Mouse pIgR Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse pIgR Antibody from R&D Systems is a goat polyclonal antibody to pIgR. This antibody reacts with human,mouse,plant,transgenic mouse. The Mouse pIgR Antibody has been validated for the following applications: Immunohistochemistry,ELISA Capture,IHC Paraffin-embedded,ELISA Development,ELISA Development (Capture),Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

pIgR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse pIgR, Lys19-Lys645, Accession # O70570

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Plant,Transgenic Mouse

specificity :

Detects mouse pIgR in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human pIgR is observed.

gene symbol :

PIGR

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Mouse pIgR antibody by Western Blot.

accessionNumbers :

O70570

applications :

Immunohistochemistry,ELISA Capture,IHC Paraffin-embedded,ELISA Development,ELISA Development (Capture),Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction

USD :

509 USD

alt names :

FLJ22667, hepatocellular carcinoma associated protein TB6, Hepatocellular carcinoma-associated protein TB6, MGC125361, MGC125362, PIgR, Poly-Ig receptor, polymeric immunoglobulin receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage