product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CLEC4F/CLECSF13 Antibody
catalog :
AF2784
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 24
Reference
Zhao D, Huang Z, Li X, Wang H, Hou Q, Wang Y, et al. GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health. elife. 2024;13: pubmed publisher
Halimani N, Nesterchuk M, Tsitrina A, Sabirov M, Andreichenko I, Dashenkova N, et al. Knockdown of Hyaluronan synthase 2 suppresses liver fibrosis in mice via induction of transcriptomic changes similar to 4MU treatment. Sci Rep. 2024;14:2797 pubmed publisher
Katoch O, Ungalara R, Kaminski T, Li Z, Dubey R, Burholt I, et al. Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease. Biomedicines. 2023;11: pubmed publisher
Zheng L, Ling W, Zhu D, Li Z, Li Y, Zhou H, et al. Roquin-1 resolves sepsis-associated acute liver injury by regulating inflammatory profiles via miRNA cargo in extracellular vesicles. iScience. 2023;26:107295 pubmed publisher
Kim A, Kui L, Kaufmann B, Kim S, Leszczyńska A, Feldstein A. Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression. J Mol Med (Berl). 2023;101:813-828 pubmed publisher
Li L, Cui L, Lin P, Liu Z, Bao S, Ma X, et al. Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers. Cell Stem Cell. 2023;30:283-299.e9 pubmed publisher
Trzaskalski N, Vulesevic B, Nguyen M, Jeraj N, Fadzeyeva E, Morrow N, et al. Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression. JCI Insight. 2023;8: pubmed publisher
Mainz R, Albers S, Haque M, Sonntag R, Treichel N, Clavel T, et al. NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease. Cells. 2022;11: pubmed publisher
Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, et al. Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. Cell. 2022;185:379-396.e38 pubmed publisher
Cohen K, Mouhadeb O, Ben Shlomo S, Langer M, Neumann A, Erez N, et al. COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver. Cell Rep. 2021;37:110026 pubmed publisher
Yang X, Lu D, Wang R, Lian Z, Lin Z, Zhuo J, et al. Single-cell profiling reveals distinct immune phenotypes that contribute to ischaemia-reperfusion injury after steatotic liver transplantation. Cell Prolif. 2021;54:e13116 pubmed publisher
Han Y, Onufer E, Huang L, Sprung R, Davidson W, Czepielewski R, et al. Enterically derived high-density lipoprotein restrains liver injury through the portal vein. Science. 2021;373: pubmed publisher
Ishikiriyama T, Nakashima H, Endo Umeda K, Nakashima M, Ito S, Kinoshita M, et al. Contrasting functional responses of resident Kupffer cells and recruited liver macrophages to irradiation and liver X receptor stimulation. PLoS ONE. 2021;16:e0254886 pubmed publisher
Daemen S, Chan M, Schilling J. Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH. STAR Protoc. 2021;2:100511 pubmed publisher
Jiang Y, Tang Y, Hoover C, Kondo Y, Huang D, Restagno D, et al. Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice. Cell Death Differ. 2021;28:3009-3021 pubmed publisher
Tsitrina A, Krasylov I, Maltsev D, Andreichenko I, Moskvina V, Ivankov D, et al. Inhibition of hyaluronan secretion by novel coumarin compounds and chitin synthesis inhibitors. Glycobiology. 2021;31:959-974 pubmed publisher
Pilling D, Karhadkar T, Gomer R. A CD209 ligand and a sialidase inhibitor differentially modulate adipose tissue and liver macrophage populations and steatosis in mice on the Methionine and Choline-Deficient (MCD) diet. PLoS ONE. 2020;15:e0244762 pubmed publisher
Remmerie A, Martens L, Thoné T, Castoldi A, Seurinck R, Pavie B, et al. Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver. Immunity. 2020;53:641-657.e14 pubmed publisher
Zhao Q, Molina Portela M, Parveen A, Adler A, Adler C, E H, et al. Heterogeneity and chimerism of endothelial cells revealed by single-cell transcriptome in orthotopic liver tumors. Angiogenesis. 2020;23:581-597 pubmed publisher
Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, et al. OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. Cell Rep. 2020;30:2237-2247.e6 pubmed publisher
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product information
brand :
R&D Systems
master code :
AF2784
SKU :
AF2784
product name :
Mouse CLEC4F/CLECSF13 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse CLEC4F/CLECSF13 Antibody from R&D Systems is a goat polyclonal antibody to CLEC4F/CLECSF13. This antibody reacts with mouse,transgenic mouse. The Mouse CLEC4F/CLECSF13 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
CLEC4F/CLECSF13
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse CLEC4F/CLECSF13, Ala65-Gly548, Accession # P70194
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse CLEC4F/CLECSF13 in direct ELISAs and Western blots.
gene symbol :
CLEC4F
top caption :
CLEC4F/CLECSF13 antibody in Mouse Liver by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P70194
applications :
Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
489 USD
alt names :
CLECSF13, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13, C-type lectin 13, C-type lectin domain family 4, member F, Galactose Particle Receptor, KCLR, KCR
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.