product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human SOX7 Antibody
catalog :
AF2766
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Chiang I, Graus M, Kirschnick N, Davidson T, Luu W, Harwood R, et al. The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023;42:e109032 pubmed publisher
Yanagida A, Corujo Simon E, Revell C, Sahu P, Stirparo G, Aspalter I, et al. Cell surface fluctuations regulate early embryonic lineage sorting. Cell. 2022;185:777-793.e20 pubmed publisher
Hong N, Zhang E, Xie H, Jin L, Zhang Q, Lu Y, et al. The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling. Cell Death Dis. 2021;12:393 pubmed publisher
Klomp J, Hyun J, Klomp J, Pajcini K, Rehman J, Malik A. Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells. J Biol Chem. 2020;295:4796-4808 pubmed publisher
Peng W, Guo L, Tang R, Liu X, Jin R, Dong J, et al. Sox7 negatively regulates prostate-specific membrane antigen (PSMA) expression through PSMA-enhancer. Prostate. 2019;79:370-378 pubmed publisher
Kim I, Kim K, Lee E, Oh D, Park C, Park S, et al. Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality. J Exp Med. 2018;215:963-983 pubmed publisher
Lilly A, Mazan A, Scott D, Lacaud G, Kouskoff V. SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development. Mech Dev. 2017;146:31-41 pubmed publisher
Lin J, Khan M, Zapiec B, Mombaerts P. Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci Rep. 2016;6:39457 pubmed publisher
product information
master code :
AF2766
SKU :
AF2766
product name :
Human SOX7 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human SOX7 Antibody from R&D Systems is a goat polyclonal antibody to SOX7. This antibody reacts with human,mouse. The Human SOX7 Antibody has been validated for the following applications: Chromatin Immunoprecipitation (ChIP),Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
SOX7
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human SOX7, Ser249-Ala345, Accession # Q9BT81
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human SOX7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SOX1, -2, -3, -9, -10, and -17 is observed.
gene symbol :
SOX7
accessionNumbers :
Q9BT81
applications :
Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
469 USD
alt names :
MGC10895, SOX7 transcription factor, SRY (sex determining region Y)-box 7, transcription factor SOX-7
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.