Mouse Carboxypeptidase A1/CPA1 Antibody | R&D Systems AF2765 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Carboxypeptidase A1/CPA1 Antibody

catalog :

AF2765

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig s3-3h	Hendley A, Rao A, Leonhardt L, Ashe S, Smith J, Giacometti S, et al. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. elife. 2021;10: pubmed publisher
immunohistochemistry; mouse; 1:300; loading ...; fig 3a	Hidalgo Sastre A, Kuebelsbeck L, Jochheim L, Staufer L, Altmayr F, Johannes W, et al. Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice. Eur J Immunol. 2021;51:1182-1194 pubmed publisher
	Miguel Escalada I, Maestro M, Balboa D, Elek A, Bernal A, Bernardo E, et al. Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster. Dev Cell. 2022;57:1922-1936.e9 pubmed publisher
	Erener S, Ellis C, Ramzy A, Glavas M, O Dwyer S, Pereira S, et al. Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice. Cell Rep Med. 2021;2:100434 pubmed publisher
	Hung J, Awasthi R, Klibanov A, Kelly K. Identification of Novel Ligands for Targeted Antifibrotic Therapy of Chronic Pancreatitis. Int J Nanomedicine. 2021;16:5495-5512 pubmed publisher
	Yum M, Han S, Fink J, Wu S, Dabrowska C, Trendafilova T, et al. Tracing oncogene-driven remodelling of the intestinal stem cell niche. Nature. 2021;594:442-447 pubmed publisher
	Padgett L, Robertson M, Anderson Baucum E, Connors C, Wu W, Mirmira R, et al. Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development. FASEB J. 2021;35:e21473 pubmed publisher
	Alonso Curbelo D, Ho Y, Burdziak C, Mååg J, Morris J, Chandwani R, et al. A gene-environment-induced epigenetic program initiates tumorigenesis. Nature. 2021;: pubmed publisher
	Kato H, Tateishi K, Fujiwara H, Ijichi H, Yamamoto K, Nakatsuka T, et al. Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis. Cancer Genomics Proteomics. 2020;17:695-705 pubmed publisher
	Zafra M, Parsons M, Kim J, Alonso Curbelo D, Goswami S, Schatoff E, et al. An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants. Cancer Discov. 2020;10:1654-1671 pubmed publisher
	Beel S, Kolloch L, Apken L, Jürgens L, Bolle A, Sudhof N, et al. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis. Nat Commun. 2020;11:3409 pubmed publisher
	Ebelt N, Zuniga E, Johnson B, Diamond D, Manuel E. 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma. Front Immunol. 2020;11:538 pubmed publisher
	Johnson B, D Alincourt Salazar M, Mackenzie Dyck S, D Apuzzo M, Shih H, Manuel E, et al. Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice. PLoS ONE. 2019;14:e0221810 pubmed publisher
	Krah N, Narayanan S, Yugawa D, Straley J, Wright C, Macdonald R, et al. Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism. Dev Cell. 2019;50:744-754.e4 pubmed publisher
	Carrer A, Trefely S, Zhao S, Campbell S, Norgard R, Schultz K, et al. Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer Discov. 2019;9:416-435 pubmed publisher
	Young C, Baker R, Howlett C, Hryciw T, Herman J, Higgs D, et al. The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice. Cell Mol Gastroenterol Hepatol. 2019;7:93-113 pubmed publisher
	Khoriaty R, Vogel N, Hoenerhoff M, Sans M, Zhu G, Everett L, et al. SEC23B is required for pancreatic acinar cell function in adult mice. Mol Biol Cell. 2017;28:2146-2154 pubmed publisher
	Krentz N, Van Hoof D, Li Z, Watanabe A, Tang M, Nian C, et al. Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. Dev Cell. 2017;41:129-142.e6 pubmed publisher

product information

master code :

AF2765

SKU :

AF2765

product name :

Mouse Carboxypeptidase A1/CPA1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Carboxypeptidase A1/CPA1 Antibody from R&D Systems is a goat polyclonal antibody to Carboxypeptidase A1/CPA1. This antibody reacts with mouse,transgenic mouse. The Mouse Carboxypeptidase A1/CPA1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunoprecipitation,Neutralization.

target :

Carboxypeptidase A1/CPA1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Carboxypeptidase A1/CPA1, Asn17-Tyr419, Accession # Q7TPZ8

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Carboxypeptidase A1/CPA1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) CPA1 is observed and approximately 10% cross-reactivity with rhCPA2, rhCPB1, and recombinant mouse CPA4 is observed.

gene symbol :

CPA1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q7TPZ8

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunoprecipitation,Neutralization

USD :

469 USD

alt names :

carboxypeptidase A1, carboxypeptidase A1 (pancreatic), CPA, CPA1, EC 3.4.17, EC 3.4.17.1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage