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company name :
R&D Systems
product type :
antibody
product name :
Mouse Nanog Antibody
catalog :
AF2729
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 15
Reference
Katoku Kikyo N, Lim S, Yuan C, Koroth J, Nakagawa Y, Bradley E, et al. The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages. PLoS Biol. 2023;21:e3002419 pubmed publisher
Sun J, Osenberg S, Irwin A, Ma L, Lee N, Xiang Y, et al. Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation. Cell Rep. 2023;42:111942 pubmed publisher
O Shea T, Ao Y, Wang S, Wollenberg A, Kim J, Ramos Espinoza R, et al. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice. Nat Commun. 2022;13:5702 pubmed publisher
Fütterer A, Talavera Gutiérrez A, Pons T, de Celis J, Gutierrez J, Domínguez Plaza V, et al. Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels. Cell Death Dis. 2021;12:637 pubmed publisher
Khoa L, Tsan Y, Mao F, Kremer D, Sajjakulnukit P, Zhang L, et al. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. 2020;27:441-458.e10 pubmed publisher
Vardhana S, Arnold P, Rosen B, Chen Y, Carey B, Huangfu D, et al. Glutamine independence is a selectable feature of pluripotent stem cells. Nat Metab. 2019;1:676-687 pubmed publisher
He S, Wang F, Zhang Y, Chen J, Liang L, Li Y, et al. Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming. Cell Discov. 2019;5:11 pubmed publisher
Kaindl J, Meiser I, Majer J, Sommer A, Krach F, Katsen Globa A, et al. Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification. Stem Cells Transl Med. 2019;8:247-259 pubmed publisher
Corsini N, Peer A, Moeseneder P, Roiuk M, Burkard T, Theussl H, et al. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 2018;22:543-558.e12 pubmed publisher
Miao Y, Gambini A, Zhang Y, Padilla Banks E, Jefferson W, Bernhardt M, et al. Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse. Biol Reprod. 2018;98:449-464 pubmed publisher
Wang P, Lan C, Xiong S, Zhao X, Shan Y, Hu R, et al. HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia. Oncotarget. 2017;8:28074-28092 pubmed publisher
Wang P, Wan W, Xiong S, Feng H, Wu N. Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer. Cell Death Discov. 2017;3:16105 pubmed publisher
Maldonado M, Luu R, Ramos M, Nam J. ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation. Stem Cell Res. 2016;17:222-227 pubmed publisher
Sun H, Liang L, Li Y, Feng C, Li L, Zhang Y, et al. Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch. Sci Rep. 2016;6:30903 pubmed publisher
Ye S, Zhang D, Cheng F, Wilson D, Mackay J, He K, et al. Wnt/β-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. J Cell Sci. 2016;129:269-76 pubmed publisher
product information
master code :
AF2729
SKU :
AF2729
product name :
Mouse Nanog Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Nanog Antibody from R&D Systems is a goat polyclonal antibody to Nanog. This antibody reacts with human,mouse. The Mouse Nanog Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Chromatin Immunoprecipitation (ChIP),Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
Nanog
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse Nanog, Trp154-Leu262, Accession # Q80Z64
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects recombinant mouse Nanog in Western blots. In this format, approximately 50% cross-reactivity with recombinant human Nanog is observed.
gene symbol :
NANOG
top caption :
Detection of Nanog antibody in D3 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q80Z64
applications :
Western Blot,Immunocytochemistry,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Chromatin Immunoprecipitation (ChIP),Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
489 USD
alt names :
FLJ12581, FLJ40451, hNanog, homeobox protein NANOG, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48, Nanog homeobox
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.