Human LMO2 Antibody | R&D Systems AF2726 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LMO2 Antibody

catalog :

AF2726

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry, chromatin immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 7

Reference
Chambers C, Cermakova K, Chan Y, Kurtz K, Wohlan K, Lewis A, et al. SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia. Cancer Res. 2023;83:983-996 pubmed publisher
Hirano K, Hosokawa H, Koizumi M, Endo Y, Yahata T, Ando K, et al. LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. elife. 2021;10: pubmed publisher
Bery N, Bataille C, Russell A, Hayes A, Raynaud F, Milhas S, et al. A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2. Sci Adv. 2021;7: pubmed publisher
Nafria M, Keane P, Ng E, Stanley E, Elefanty A, Bonifer C. Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells. Cell Rep. 2020;31:107691 pubmed publisher
Li L, Mitra A, Cui K, Zhao B, Choi S, Lee J, et al. Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia. Blood. 2020;135:2252-2265 pubmed publisher
Stanulovic V, Cauchy P, Assi S, Hoogenkamp M. LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage. Nucleic Acids Res. 2017;45:9874-9888 pubmed publisher
Cheng H, Ang H, A El Farran C, Li P, Fang H, Liu T, et al. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. Nat Commun. 2016;7:13396 pubmed publisher

product information

master code :

AF2726

SKU :

AF2726

product name :

Human LMO2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human LMO2 Antibody from R&D Systems is a goat polyclonal antibody to LMO2. This antibody reacts with human,mouse. The Human LMO2 Antibody has been validated for the following applications: ChIP (chromatin immunoprecipit,Western Blot,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing,Flow Cytometry,Immunocytochemistry.

target :

LMO2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human LMO2, Ser2-Ile158, Accession # P25791

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human LMO2 in direct ELISAs and Western blots.

gene symbol :

LMO2

top caption :

Detection of LMO2 antibody in K562 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

P25791

applications :

ChIP (chromatin immunoprecipit,Western Blot,Chromatin Immunoprecipitation (ChIP),Chromatin Immunoprecipitation Sequencing,Flow Cytometry,Immunocytochemistry

USD :

469 USD

alt names :

Cysteine-rich protein TTG-2, LIM domain only 2 (rhombotin-like 1), LIM domain only protein 2, LMO-2, RBTN2, RBTN2rhombotin-2, RBTNL1, RBTNL1rhombotin-like 1, RHOM2, RHOM2T-cell translocation protein 2, T-cell translocation gene 2, TTG2, TTG2rhombotin 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage