product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-Src (Y419) Antibody
catalog :
AF2685
quantity :
100 ug (also 25 ug)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Ruiz Sáenz A, Atreya C, Wang C, Pan B, Dreyer C, Brunen D, et al. A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors. Nat Cancer. 2023;4:240-256 pubmed publisher
R xf6 sch L, Herter S, Najafi S, Ridinger J, Peterziel H, Cinatl J, et al. ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein. Mol Oncol. 2023;17:37-58 pubmed publisher
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed publisher
Ramirez Ricardo J, Leal Orta E, Martínez Baeza E, Ortiz Mendoza C, Breton Mora F, Herrera Torres A, et al. Circulating extracellular vesicles from patients with breast cancer enhance migration and invasion via a Src‑dependent pathway in MDA‑MB‑231 breast cancer cells. Mol Med Rep. 2020;22:1932-1948 pubmed publisher
Mao Y, Sun S, Irvine K. Role and regulation of Yap in KrasG12D-induced lung cancer. Oncotarget. 2017;8:110877-110889 pubmed publisher
Pak J, Bashir Q, Kim I, Hong S, Maeng S, Bahk Y, et al. Clonorchis sinensis excretory-secretory products promote the migration and invasion of cholangiocarcinoma cells by activating the integrin ?4-FAK/Src signaling pathway. Mol Biochem Parasitol. 2017;214:1-9 pubmed publisher
product information
master code :
AF2685
SKU :
AF2685
product name :
Human Phospho-Src (Y419) Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Phospho-Src (Y419) Antibody from R&D Systems is a rabbit polyclonal antibody to Src. This antibody reacts with human,mouse. The Human Phospho-Src (Y419) Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Simple Western.
target :
Src
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Phosphopeptide containing human Src Y419 site
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human Src family members when phosphorylated at sites corresponding to Y419 of human Src in Western blots.
gene symbol :
SRC
top caption :
Detection of Human Phospho-Src (Y419) antibody by Western Blot.
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Simple Western
USD :
399 USD
alt names :
ASV, c-Src, EC 2.7.10, EC 2.7.10.2, pp60c-src, Rous sarcoma, RSVgp4, tyrosine kinase pp60c-src, tyrosine-protein kinase SRC-1, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.