product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Gas1 Antibody
catalog :
AF2636
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Lee J, Kim Y, Ataliotis P, Kim H, Kim D, Bennett D, et al. Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development. Sci Rep. 2023;13:12309 pubmed publisher
Marczenke M, Sunaga Franze D, Popp O, Althaus I, Sauer S, Mertins P, et al. GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium. Development. 2021;148: pubmed publisher
Chapouly C, Hollier P, Guimbal S, Cornuault L, Gadeau A, Renault M. Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes). Arterioscler Thromb Vasc Biol. 2020;40:e336-e349 pubmed publisher
Kim Y, Lee J, Seppala M, Cobourne M, Kim S. Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration. Nat Commun. 2020;11:1994 pubmed publisher
product information
master code :
AF2636
SKU :
AF2636
product name :
Human Gas1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Gas1 Antibody from R&D Systems is a goat polyclonal antibody to Gas1. This antibody reacts with human,mouse. The Human Gas1 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Western Blot.
target :
Gas1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Gas1, Leu40-Ser318, Accession # P54826
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human Gas1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant mouse Gas1 is observed.
gene symbol :
GAS1
accessionNumbers :
P54826
applications :
Immunocytochemistry,Immunohistochemistry,Western Blot
USD :
459 USD
alt names :
GAS-1, growth arrest-specific 1, Growth arrest-specific gene-1, growth arrest-specific protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.