Mouse Klotho ▀ Antibody | R&D Systems AF2619 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Klotho ▀ Antibody

catalog :

AF2619

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Kobayashi K, Iwasa K, Azuma Suzuki R, Kawauchi T, Nabeshima Y. Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth. Life Sci Alliance. 2023;6: pubmed publisher
Wang S, Zha L, Cui X, Yeh Y, Liu R, Jing J, et al. Epigenetic Regulation of Hepatic Lipid Metabolism by DNA Methylation. Adv Sci (Weinh). 2023;10:e2206068 pubmed publisher
Wu Y, Ren Z, Zhu S, Wu Y, Wang G, Zhang H, et al. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway. Acta Pharmacol Sin. 2022;43:1473-1483 pubmed publisher
Ying L, Li N, He Z, Zeng X, Nan Y, Chen J, et al. Fibroblast growth factor 21 Ameliorates diabetes-induced endothelial dysfunction in mouse aorta via activation of the CaMKK2/AMPKα signaling pathway. Cell Death Dis. 2019;10:665 pubmed publisher
Bao L, Yin J, Gao W, Wang Q, Yao W, Gao X. A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway. Br J Pharmacol. 2018;175:3379-3393 pubmed publisher
Gilroy C, Roberts S, Chilkoti A. Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action. J Control Release. 2018;277:154-164 pubmed publisher
BonDurant L, Ameka M, Naber M, Markan K, Idiga S, Acevedo M, et al. FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms. Cell Metab. 2017;25:935-944.e4 pubmed publisher

product information

master code :

AF2619

SKU :

AF2619

product name :

Mouse Klotho ▀ Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Klotho ß Antibody from R&D Systems is a goat polyclonal antibody to Klotho beta. This antibody reacts with human,mouse,transgenic mouse. The Mouse Klotho ß Antibody has been validated for the following applications: Western Blot,Immunohistochemistry.

target :

Klotho beta

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Klotho ▀ (R D Systems, Catalog # 2619-KB), Phe53-Leu995, Accession # NP_112457

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse Klotho ▀ in direct ELISAs and Western blots. In these formats, approximately 5% cross-reactivity with recombinant mouse Klotho is observed.

gene symbol :

KLB

accessionNumbers :

NP_112457

applications :

Western Blot,Immunohistochemistry

USD :

509 USD

alt names :

beta-klotho, betaKlotho, BKL, KLB, klotho beta, klotho beta like, klotho beta-like protein, MGC142213

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage