Human TLR2 Antibody | R&D Systems AF2616 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TLR2 Antibody

catalog :

AF2616

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

R&D Systems product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig 4k western blot; human; loading ...; fig 4i	Luo X, Gong H, Gao H, Wu Y, Sun W, Li Z, et al. Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2. Cell Death Differ. 2021;: pubmed publisher
	Shen P, Serve S, Wu P, Liu X, Dai Y, Dur xe1 n Hern xe1 ndez N, et al. NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age-related osteoarthritis. Proc Natl Acad Sci U S A. 2023;120:e2207993120 pubmed publisher
	Youn S, Jiang F, Won H, Hong D, Kang T, Park Y, et al. PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway. Int J Mol Sci. 2022;23: pubmed publisher
	Karavyraki M, Porter R. Evidence of a role for interleukin-6 in anoikis resistance in oral squamous cell carcinoma. Med Oncol. 2022;39:60 pubmed publisher
	Li T, Yang Y, Li Y, Wang Z, Ma F, Luo R, et al. Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein. J Clin Invest. 2022;132: pubmed publisher
	He X, Howard B, Liu Y, Neumann A, Li L, Menon N, et al. LYSMD3: A mammalian pattern recognition receptor for chitin. Cell Rep. 2021;36:109392 pubmed publisher
	Flis E, Barber G, Nulty C, Keogh B, McGuirk P, Anand A, et al. Identification of TLR2 Signalling Mechanisms Which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression. Cancers (Basel). 2021;13: pubmed publisher
	Jun J, Lau L. CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling. Nat Commun. 2020;11:1242 pubmed publisher
	Pandruvada S, Ebersole J, Huja S. Inhibition of osteoclastogenesis by opsonized Porphyromonas gingivalis. FASEB Bioadv. 2019;1:213-226 pubmed publisher
	Huang P, Low P, Wang I, Hsu S, Angata T. Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses. J Biol Chem. 2018;293:19645-19658 pubmed publisher
	Dzamko N, Gysbers A, Perera G, Bahar A, Shankar A, Gao J, et al. Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology. Acta Neuropathol. 2017;133:303-319 pubmed publisher

product information

master code :

AF2616

SKU :

AF2616

product name :

Human TLR2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TLR2 Antibody from R&D Systems is a goat polyclonal antibody to TLR2. This antibody reacts with human. The Human TLR2 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Cell-based ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

TLR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TLR2, Glu21-Leu590, Accession # O60603

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human TLR2 in ELISAs and Western blots. In sandwich ELISAs, less than 1% cross-reactivity with recombinant mouse TLR2 and less than 0.3% cross-reactivity with recombinant human (rh) TLR3 and rhTLR4/MD-2 is observed.

gene symbol :

TLR2

top caption :

Detection of Human TLR2 antibody by Western Blot.

accessionNumbers :

O60603

applications :

Immunohistochemistry,Western Blot,Cell-based ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair),CyTOF-ready

USD :

489 USD

alt names :

CD282, CD282 antigen, TIL4CD282, toll/interleukin 1 receptor-like 4, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage