product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human HAPLN1 Antibody
catalog :
AF2608
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 11
Reference
Werren E, LaForce G, Srivastava A, Perillo D, Li S, Johnson K, et al. TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome. Nat Commun. 2024;15:1640 pubmed publisher
Wiedmann L, De Angelis Rigotti F, Vaquero Siguero N, Donato E, Espinet E, Moll I, et al. HAPLN1 potentiates peritoneal metastasis in pancreatic cancer. Nat Commun. 2023;14:2353 pubmed publisher
H xf6 hn L, Hu xdf ler W, Richter A, Smalla K, Birkl Toeglhofer A, Birkl C, et al. Extracellular Matrix Changes in Subcellular Brain Fractions and Cerebrospinal Fluid of Alzheimer's Disease Patients. Int J Mol Sci. 2023;24: pubmed publisher
Budhraja R, Saraswat M, De Graef D, Ranatunga W, Ramarajan M, Mousa J, et al. N-glycoproteomics reveals distinct glycosylation alterations in NGLY1-deficient patient-derived dermal fibroblasts. J Inherit Metab Dis. 2023;46:76-91 pubmed publisher
Schmidt S, Holzer M, Arendt T, Sonntag M, Morawski M. Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-acan Mouse Model. Biomolecules. 2022;12: pubmed publisher
Schob S, Puchta J, Winter K, Michalski D, Mages B, Martens H, et al. Surfactant protein C is associated with perineuronal nets and shows age-dependent changes of brain content and hippocampal deposits in wildtype and 3xTg mice. J Chem Neuroanat. 2021;118:102036 pubmed publisher
Nojima K, Miyazaki H, Hori T, Vargova L, Oohashi T. Assessment of Possible Contributions of Hyaluronan and Proteoglycan Binding Link Protein 4 to Differential Perineuronal Net Formation at the Calyx of Held. Front Cell Dev Biol. 2021;9:730550 pubmed publisher
Hunyadi A, Gaál B, Matesz C, Mészár Z, Morawski M, Reimann K, et al. Distribution and classification of the extracellular matrix in the olfactory bulb. Brain Struct Funct. 2020;225:321-344 pubmed publisher
Eill G, Sinha A, Morawski M, Viapiano M, Matthews R. The protein tyrosine phosphatase RPTPζ/phosphacan is critical for perineuronal net structure. J Biol Chem. 2020;295:955-968 pubmed publisher
Sonntag M, Blosa M, Schmidt S, Reimann K, Blum K, Eckrich T, et al. Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets. BMC Biol. 2018;16:99 pubmed publisher
Eskici N, Erdem Ozdamar S, Dayangac Erden D. The altered expression of perineuronal net elements during neural differentiation. Cell Mol Biol Lett. 2018;23:5 pubmed publisher
product information
master code :
AF2608
SKU :
AF2608
product name :
Human HAPLN1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human HAPLN1 Antibody from R&D Systems is a goat polyclonal antibody to HAPLN1. This antibody reacts with human,mouse,rat,transgenic mouse. The Human HAPLN1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture.
target :
HAPLN1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human HAPLN1 (R D Systems, Catalog # 2608-HP), Asp16-Asn354, Accession # P10915
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human HAPLN1 in direct ELISAs and Western blots. In these formats, this antibody shows approximately 5% cross-reactivity with recombinant human HAPLN4.
gene symbol :
HAPLN1
top caption :
Detection of Human HAPLN1 by Immunocytochemistry/Immunofluorescence
accessionNumbers :
P10915
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture
USD :
479 USD
alt names :
Cartilage link protein, Cartilage-link protein, Cartilage-linking protein 1, CRTL1, CRTL1cartilage linking protein 1, hyaluronan and proteoglycan link protein 1, Proteoglycan link protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.