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company name :
R&D Systems
product type :
antibody
product name :
Human GATA-3 Antibody
catalog :
AF2605
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 30
Reference
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Inage Y, Fujimori K, Takasu M, Matsui K, Kinoshita Y, Morimoto K, et al. Fetal Kidney Grafts and Organoids from Microminiature Pigs: Establishing a Protocol for Production and Long-Term Cryopreservation. Int J Mol Sci. 2024;25: pubmed publisher
Yamamoto S, Matsui K, Kinoshita Y, Hiroshi Sasaki -, Sekine H, Saito Y, et al. Successful reconstruction of the rat ureter by a syngeneic collagen tube with a cardiomyocyte sheet. Regen Ther. 2023;24:561-567 pubmed publisher
Yu L, Logsdon D, Pinzon Arteaga C, Duan J, Ezashi T, Wei Y, et al. Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk. Cell Stem Cell. 2023;30:1246-1261.e9 pubmed publisher
Lermant A, Rabussier G, Lanz H, Davidson L, Porter I, Murdoch C. Development of a human iPSC-derived placental barrier-on-chip model. iScience. 2023;26:107240 pubmed publisher
Li J, Zhu Q, Cao J, Liu Y, Lu Y, Sun Y, et al. Cynomolgus monkey embryo model captures gastrulation and early pregnancy. Cell Stem Cell. 2023;30:362-377.e7 pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Groenewegen E, Rudraraju R, Neil J, et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. Nat Commun. 2022;13:5943 pubmed publisher
Hiratsuka K, Miyoshi T, Kroll K, Gupta N, Valerius M, Ferrante T, et al. Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Sci Adv. 2022;8:eabq0866 pubmed publisher
Ohgushi M, Taniyama N, Vandenbon A, Eiraku M. Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model. Cell Rep. 2022;39:110973 pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Groenewegen E, Rudraraju R, Neil J, et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. bioRxiv. 2022;: pubmed publisher
Lawrence M, Elhendawi M, Morlock M, Liu W, Liu S, Palakkan A, et al. Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity. iScience. 2022;25:103884 pubmed publisher
Saito Y, Matsumoto N, Yamanaka S, Yokoo T, Kobayashi E. Beneficial Impact of Interspecies Chimeric Renal Organoids Against a Xenogeneic Immune Response. Front Immunol. 2022;13:848433 pubmed publisher
Bejoy J, Qian E, WOODARD L. Accelerated protocol for the differentiation of podocytes from human pluripotent stem cells. STAR Protoc. 2021;2:100898 pubmed publisher
Zhu M, Shahbazi M, Martin A, Zhang C, Sozen B, Borsos M, et al. Human embryo polarization requires PLC signaling to mediate trophectoderm specification. elife. 2021;10: pubmed publisher
Meistermann D, Bruneau A, Loubersac S, Reignier A, Firmin J, François Campion V, et al. Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification. Cell Stem Cell. 2021;28:1625-1640.e6 pubmed publisher
Howden S, Wilson S, Groenewegen E, Starks L, Forbes T, Tan K, et al. Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk. Cell Stem Cell. 2020;: pubmed publisher
Uchimura K, Wu H, Yoshimura Y, Humphreys B. Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling. Cell Rep. 2020;33:108514 pubmed publisher
Shahbazi M, Wang T, Tao X, Weatherbee B, Sun L, Zhan Y, et al. Developmental potential of aneuploid human embryos cultured beyond implantation. Nat Commun. 2020;11:3987 pubmed publisher
Yu A, Zhao L, Eaton K, Ho S, Chen J, Poe S, et al. Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis. Cell Rep. 2020;31:107471 pubmed publisher
Tan Z, Rak Raszewska A, Skovorodkin I, Vainio S. Mouse Embryonic Stem Cell-Derived Ureteric Bud Progenitors Induce Nephrogenesis. Cells. 2020;9: pubmed publisher
Li C, Li X, Bi Z, Sugino K, Wang G, Zhu T, et al. Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. elife. 2020;9: pubmed publisher
Nomura S, Takahashi H, Suzuki J, Kuwahara M, Yamashita M, Sawasaki T. Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro. Sci Rep. 2019;9:17335 pubmed publisher
Dvorakova M, Macova I, Bohuslavova R, Anderova M, Fritzsch B, Pavlinkova G. Early ear neuronal development, but not olfactory or lens development, can proceed without SOX2. Dev Biol. 2020;457:43-56 pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Soo J, Scurr M, Spijker H, et al. A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids. J Am Soc Nephrol. 2019;30:1811-1823 pubmed publisher
Combes A, Phipson B, Lawlor K, Dorison A, Patrick R, Zappia L, et al. Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk. Development. 2019;146: pubmed publisher
Howden S, Vanslambrouck J, Wilson S, Tan K, Little M. Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation. EMBO Rep. 2019;20: pubmed publisher
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Shahi P, Wang C, Chou J, Hagerling C, Gonzalez Velozo H, Ruderisch A, et al. GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis. Oncogene. 2017;36:5567-5575 pubmed publisher
product information
master code :
AF2605
SKU :
AF2605
product name :
Human GATA-3 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human GATA-3 Antibody from R&D Systems is a goat polyclonal antibody to GATA-3. This antibody reacts with bovine,human,mouse,porcine,primate - chlorocebus pygerythrus (vervet monkey),primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),rat,xenograft. The Human GATA-3 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Simple Western.
target :
GATA-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human GATA-3, Pro135-Ser258, Accession # P23771
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Bovine,Human,Mouse,Porcine,Primate - Chlorocebus pygerythrus (Vervet Monkey),Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Rat,Xenograft
specificity :
Detects human and mouse GATA-3 in direct ELISAs and Western blots.
gene symbol :
GATA3
top caption :
Detection of Human and Mouse GATA-3 antibody by Western Blot.
accessionNumbers :
P23771
applications :
Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Simple Western
USD :
499 USD
alt names :
131320, GATA binding protein 3, GATA3, GATA-binding factor 3, GATA-binding protein 3, HDRMGC5199, MGC2346, MGC5445, trans-acting T-cell-specific transcription factor GATA-3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.