product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human FGF-23 Antibody
catalog :
AF2604
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, neutralization, immunoprecipitation
more info or order :
citations: 4
Reference
The E, Zhai Y, Yao Q, Ao L, Fullerton D, Meng X. Molecular Interaction of Soluble Klotho with FGF23 in the Pathobiology of Aortic Valve Lesions Induced by Chronic Kidney Disease. Int J Biol Sci. 2024;20:3412-3425 pubmed publisher
Brandebura A, Kolson D, Amick E, Ramadan J, Kersting M, Nichol R, et al. Transcriptional profiling reveals roles of intercellular Fgf9 signaling in astrocyte maturation and synaptic refinement during brainstem development. J Biol Chem. 2022;298:102176 pubmed publisher
Yanucil C, Kentrup D, Campos I, Czaya B, Heitman K, Westbrook D, et al. Soluble α-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney disease. Kidney Int. 2022;102:261-279 pubmed publisher
Smith E, Tan S, Holt S, Hewitson T. FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts. Sci Rep. 2017;7:3345 pubmed publisher
product information
master code :
AF2604
SKU :
AF2604
product name :
Human FGF-23 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human FGF-23 Antibody from R&D Systems is a goat polyclonal antibody to FGF-23. This antibody reacts with human,mouse,rat. The Human FGF-23 Antibody has been validated for the following applications: Neutralization,Immunoprecipitation,Immunohistochemistry,In vivo assay,Western Blot.
target :
FGF-23
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human FGF-23, Tyr25-Ile251, Accession # Q9GZV9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human FGF-23 in direct ELISAs and Western blots.
gene symbol :
FGF23
endotoxin note :
<0.24 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by FGF-23 and Neutralization by Human FGF-23 Antibody.
accessionNumbers :
Q9GZV9
applications :
Neutralization,Immunoprecipitation,Immunohistochemistry,In vivo assay,Western Blot
USD :
519 USD
alt names :
ADHR, FGF23, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.