product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human SOX3 Antibody
catalog :
AF2569
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Whiley P, Nathaniel B, Stanton P, Hobbs R, Loveland K. Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours. Front Cell Dev Biol. 2023;11:1237273 pubmed publisher
Prakash Yadav R, Leskinen S, Ma L, M xe4 kel xe4 J, Kotaja N. Chromatin remodelers HELLS, WDHD1 and BAZ1A are dynamically expressed during mouse spermatogenesis. Reproduction. 2023;165:49-63 pubmed publisher
Sun Y, Wang L, Zhu T, Wu B, Wang G, Luo Z, et al. Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022;38:110542 pubmed publisher
Thomson E, Dawson R, H ng C, Adikusuma F, Piltz S, Thomas P. The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development. PLoS ONE. 2021;16:e0258538 pubmed publisher
Suzuki S, McCarrey J, Hermann B. An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia. Cell Rep. 2021;34:108752 pubmed publisher
McAninch D, Mäkelä J, La H, Hughes J, Lovell Badge R, Hobbs R, et al. SOX3 promotes generation of committed spermatogonia in postnatal mouse testes. Sci Rep. 2020;10:6751 pubmed publisher
Legrand J, Chan A, La H, Rossello F, Ankö M, Fuller Pace F, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278 pubmed publisher
La H, Mäkelä J, Chan A, Rossello F, Nefzger C, Legrand J, et al. Identification of dynamic undifferentiated cell states within the male germline. Nat Commun. 2018;9:2819 pubmed publisher
product information
master code :
AF2569
SKU :
AF2569
product name :
Human SOX3 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human SOX3 Antibody from R&D Systems is a goat polyclonal antibody to SOX3. This antibody reacts with human,mouse,transgenic mouse. The Human SOX3 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot.
target :
SOX3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human SOX3, Met1-Leu230, Accession # P41225
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human SOX3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) SOX2, rhSOX7, rhSOX10, and rhSOX17 is observed.
gene symbol :
SOX3
top caption :
SOX3 antibody in NTera-2 Human Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
P41225
applications :
Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot
USD :
469 USD
alt names :
GHDX, MRGH, panhypopituitarism, PHP, PHPX, SOXB, SRY (sex determining region Y)-box 3, transcription factor SOX-3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.