Human/Rhesus Macaque IL-18/IL-1F4 Antibody | R&D Systems AF2548 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Rhesus Macaque IL-18/IL-1F4 Antibody

catalog :

AF2548

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rhesus macaque

application :

western blot, ELISA, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 6

Reference
Exconde P, Hernandez Chavez C, Bourne C, Richards R, Bray M, Lopez J, et al. The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases. Cell Rep. 2023;42:113581 pubmed publisher
Kahm Y, Kim I, Kim R. RanBP1: A Potential Therapeutic Target for Cancer Stem Cells in Lung Cancer and Glioma. Int J Mol Sci. 2023;24: pubmed publisher
Exconde P, Hernandez Chavez C, Bray M, Lopez J, Srivastava T, Egan M, et al. The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases. bioRxiv. 2023;: pubmed publisher
Wang Q, Hsiao J, Yardeny N, Huang H, O Mara C, Orth He E, et al. The NLRP1 and CARD8 inflammasomes detect reductive stress. Cell Rep. 2023;42:111966 pubmed publisher
Rao S, Chen Q, Wang Q, Orth He E, Saoi M, Griswold A, et al. M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome. Nat Chem Biol. 2022;18:565-574 pubmed publisher
Xu Y, Wang J, Xu W, Ding F, Ding W. Prohibitin 2-mediated mitophagy attenuates renal tubular epithelial cells injury by regulating mitochondrial dysfunction and NLRP3 inflammasome activation. Am J Physiol Renal Physiol. 2019;316:F396-F407 pubmed publisher

product information

master code :

AF2548

SKU :

AF2548

product name :

Human/Rhesus Macaque IL-18/IL-1F4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Rhesus Macaque IL-18/IL-1F4 Antibody from R&D Systems is a goat polyclonal antibody to IL-18/IL-1F4. This antibody reacts with human,rhesus macaque. The Human/Rhesus Macaque IL-18/IL-1F4 Antibody has been validated for the following applications: Bioassay,Western Blot,Neutralization,ELISA,Simple Western,Immunocytochemistry,Knockout Validated.

target :

IL-18/IL-1F4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant rhesus macaque IL-18/IL-1F4, Tyr37-Asp193, Accession # AAK13416

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Rhesus Macaque

specificity :

Detects rhesus macaque IL-18/IL-1F4 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse IL-18, recombinant rat IL-18, and recombinant porcine IL-18 is observed.

gene symbol :

IL18

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human IL-18/IL-1F4 antibody by Western Blot.

accessionNumbers :

AAK13416

applications :

Bioassay,Western Blot,Neutralization,ELISA,Simple Western,Immunocytochemistry,Knockout Validated

USD :

519 USD

alt names :

Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage