Human DDR2 Antibody | R&D Systems AF2538 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human DDR2 Antibody

catalog :

AF2538

quantity :

100 ug (also 25 ug)

price :

529 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 6

Reference
Han T, Mignatti P, Abramson S, Attur M. Periostin interaction with discoidin domain receptor-1 (DDR1) promotes cartilage degeneration. PLoS ONE. 2020;15:e0231501 pubmed publisher
Jalan A, Sammon D, Hartgerink J, Brear P, Stott K, Hamaia S, et al. Chain alignment of collagen I deciphered using computationally designed heterotrimers. Nat Chem Biol. 2020;16:423-429 pubmed publisher
Nguyen E, Pereira B, Lawrence M, Ma X, Rebello R, Chan H, et al. Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment. Mol Cell Proteomics. 2019;: pubmed publisher
Tu M, Lee F, Jones R, Kimball A, Saravia E, Graziano R, et al. Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy. Sci Adv. 2019;5:eaav2437 pubmed publisher
Yeung D, Shanker N, Sohail A, Weiss B, Wang C, Wellmerling J, et al. Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I. J Mol Biol. 2019;431:368-390 pubmed publisher
Majkowska I, Shitomi Y, Ito N, Gray N, Itoh Y. Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts. J Biol Chem. 2017;292:6633-6643 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2538

SKU :

AF2538

product name :

Human DDR2 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human DDR2 Antibody from R&D Systems is a goat polyclonal antibody to DDR2. This antibody reacts with human,mouse. The Human DDR2 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry,Immunohistochemistry,Simple Western.

target :

DDR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 2.5 ug/mL, Immunohistochemistry 5-15 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human DDR2, Gln24-Arg399, Accession # Q16832

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human DDR2 in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human DDR1 is observed.

gene symbol :

DDR2

top caption :

Detection of Human DDR2 antibody by Simple WesternTM.

accessionNumbers :

Q16832

applications :

Immunohistochemistry,Simple Western,Immunoprecipitation,Western Blot,Immunocytochemistry

USD :

529 USD

alt names :

CD167 antigen-like family member B, CD167b antigen, Discoidin domain receptor 2, discoidin domain receptor family, member 2, discoidin domain receptor tyrosine kinase 2, discoidin domain-containing receptor 2, EC 2.7.10, EC 2.7.10.1, hydroxyaryl-protein kinase, migration-inducing gene 16 protein, neurotrophic tyrosine kinase receptor related 3, Neurotrophic tyrosine kinase, receptor-related 3, NTRKR3cell migration-inducing protein 20, Receptor protein-tyrosine kinase TKT, TKT, TKTMIG20a, Trk3, Tyro-10, TYRO10, Tyrosine-protein kinase TYRO10, tyrosylprotein kinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage