product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Myocilin Antibody
catalog :
AF2537
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rhesus macaque
application :
western blot, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 2
Reference
Lynch J, Dolman A, Guo C, Dolan K, Xiang C, Reda S, et al. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle. PLoS ONE. 2018;13:e0206801 pubmed publisher
Lynch J, Li B, Katoli P, Xiang C, Leehy B, Rangaswamy N, et al. Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. J Biol Chem. 2018;293:20137-20156 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2537
SKU :
AF2537
product name :
Human Myocilin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Myocilin Antibody from R&D Systems is a goat polyclonal antibody to Myocilin. This antibody reacts with human,primate - macaca mulatta (rhesus macaque),transgenic mouse. The Human Myocilin Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Simple Western.
target :
Myocilin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 50 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Myocilin, Arg33-Met504, Accession # Q99972
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Primate - Macaca mulatta (Rhesus Macaque),Transgenic Mouse
specificity :
Detects human Myocilin in direct ELISAs and Western blots.
gene symbol :
MYOC
top caption :
Detection of Human Myocilin antibody by Western Blot.
accessionNumbers :
Q99972
applications :
Simple Western,Western Blot,Immunocytochemistry
USD :
489 USD
alt names :
GLC1A, GLC1Amyocilin, GPOA, JOAG, JOAG1, MYOC, myocilin, trabecular meshwork inducible glucocorticoid response, TIGR, TIGRmutated trabecular meshwork-induced glucocorticoid response protein, Trabecular meshwork-induced glucocorticoid response protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.