product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse MMR/CD206 Antibody
catalog :
AF2535
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 163
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig s7f
Cortes J, Filip I, Albero R, Patiño Galindo J, Quinn S, Lin W, et al. Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma. Cell Rep. 2022;39:110695 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 5c
Zheng Z, Chen J, Lyu H, Lam S, Lu G, Chan W, et al. Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage. Stroke Vasc Neurol. 2021;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5e
Li J, Sun Z, Luo G, Wang S, Cui H, Yao Z, et al. Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult. Front Immunol. 2021;12:649285 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig s3b
Lindfors S, Polianskyte Prause Z, Bouslama R, Lehtonen E, Mannerla M, Nisen H, et al. Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia. 2021;64:1866-1879 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Chu A, Kok S, TSUI J, Lin M, Aguirre B, Wadehra M. Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface. J Reprod Immunol. 2021;145:103309 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1a
Li Z, Song Y, He T, Wen R, Li Y, Chen T, et al. M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice. Theranostics. 2021;11:1232-1248 pubmed publisher
Korte N, Barkaway A, Wells J, Freitas F, Sethi H, Andrews S, et al. Inhibiting Ca2+ channels in Alzheimer's disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. Nat Neurosci. 2024;27:2086-2100 pubmed publisher
Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, et al. Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice. Int Immunopharmacol. 2024;132:111962 pubmed publisher
Mader M, Napole A, Wu D, Atkins M, Scavetti A, Shibuya Y, et al. Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis. Nat Neurosci. 2024;27:901-912 pubmed publisher
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Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, et al. CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023;42:112092 pubmed publisher
Park B, Wu D, Kwon K, Kim M, Kim T, Lee J, et al. Implantation and tracing of green fluorescent protein-expressing adipose-derived stem cells in peri-implant capsular fibrosis. Stem Cell Res Ther. 2023;14:22 pubmed publisher
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Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, et al. IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders. Int Immunopharmacol. 2023;114:109479 pubmed publisher
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product information
brand :
R&D Systems
master code :
AF2535
SKU :
AF2535
product name :
Mouse MMR/CD206 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse MMR/CD206 Antibody from R&D Systems is a goat polyclonal antibody to MMR/CD206/Mannose Receptor. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse MMR/CD206 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Flow Cytometry,IHC-Pr,Immunocytochemistry,IHC/IF,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,CyTOF-ready.
target :
MMR/CD206
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, CyTOF-ready
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse MMR/CD206, Leu19-Ala1388, Accession # Q2HZ94
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse MMR/CD206 in direct ELISAs and Western blots. In direct ELISAs, less than 45% cross-reactivity with recombinant human MMR is observed.
gene symbol :
MRC1
top caption :
Detection of Mouse MMR/CD206 antibody by Western Blot.
accessionNumbers :
Q2HZ94
applications :
CyTOF-ready,IHC/IF,IHC-Pr,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunofluorescence,Immunocytochemistry
USD :
499 USD
alt names :
CD206, CLEC13D, CLEC13Dmacrophage mannose receptor 1, C-type lectin domain family 13 member D, mannose receptor, C type 1, MMRCD206 antigen, MRC1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.