Human MMR/CD206 Antibody | R&D Systems AF2534 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human MMR/CD206 Antibody

catalog :

AF2534

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; loading ...; fig 1c	Bajor M, Graczyk Jarzynka A, Marhelava K, Burdzińska A, Muchowicz A, Góral A, et al. PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells. J Immunother Cancer. 2022;10: pubmed publisher
western blot; mouse; 1:1000; loading ...; fig s3a	Fang Y, Jiang Q, Li S, Zhu H, Xu R, Song N, et al. Opposing functions of β-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3. Cell Death Differ. 2021;28:1822-1836 pubmed publisher
	Chang Y, Liu J, Jiang Y, Ma A, Yeo Y, Guo Q, et al. Graph Fourier transform for spatial omics representation and analyses of complex organs. Res Sq. 2024;: pubmed publisher
	Antwi M, Dumitriu G, Sim xf3 n Santamaria J, Romano J, Li R, Smedsr xf8 d B, et al. Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmpgt/gt mouse model of slowly progressing liver fibrosis. PLoS ONE. 2023;18:e0293526 pubmed publisher
	Digifico E, Erreni M, Mannarino L, Marchini S, Ummarino A, Anfray C, et al. Important functional role of the protein osteopontin in the progression of malignant pleural mesothelioma. Front Immunol. 2023;14:1116430 pubmed publisher
	Southerland K, Xu Y, Peters D, Wei X, Lin X, Xiang Y, et al. Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells. bioRxiv. 2023;: pubmed publisher
	Larionova I, Kiselev A, Kazakova E, Liu T, Patysheva M, Iamshchikov P, et al. Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF. Front Immunol. 2023;14:1000497 pubmed publisher
	Heng Y, Zhu X, Lin H, Jingyu M, Ding X, Tao L, et al. CD206+ tumor-associated macrophages interact with CD4+ tumor-infiltrating lymphocytes and predict adverse patient outcome in human laryngeal squamous cell carcinoma. J Transl Med. 2023;21:167 pubmed publisher
	Yilmaz M, Demir E, Firatli Y, Firatli E, G xfc rsoy U. Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease. Curr Issues Mol Biol. 2022;44:4704-4713 pubmed publisher
	Horiba S, Kami R, Tsutsui T, Hosoi J. IL-34 Downregulation‒Associated M1/M2 Macrophage Imbalance Is Related to Inflammaging in Sun-Exposed Human Skin. JID Innov. 2022;2:100112 pubmed publisher
	Li G, Li X, Yang L, Wang S, Dai Y, Fekry B, et al. Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice. Life Sci Alliance. 2022;5: pubmed publisher
	Madden P, Thomas Y, Blair R, Samer S, Doyle M, Midkiff C, et al. An immunoPET probe to SARS-CoV-2 reveals early infection of the male genital tract in rhesus macaques. Res Sq. 2022;: pubmed publisher
	Larsen A, Sim xf3 n Santamar xed a J, Elvevold K, Ericzon B, Mortensen K, McCourt P, et al. Autofluorescence in freshly isolated adult human liver sinusoidal cells. Eur J Histochem. 2021;65: pubmed publisher
	Finlin B, Memetimin H, Confides A, Zhu B, Westgate P, Dupont Versteegden E, et al. Macrophages expressing uncoupling protein 1 increase in adipose tissue in response to cold in humans. Sci Rep. 2021;11:23598 pubmed publisher
	Dymowska M, Aksamit A, Zielniok K, Kniotek M, Kaleta B, Roszczyk A, et al. Interaction between Macrophages and Human Mesenchymal Stromal Cells Derived from Bone Marrow and Wharton's Jelly-A Comparative Study. Pharmaceutics. 2021;13: pubmed publisher
	Gao Z, Lu A, Daquinag A, Yu Y, Huard M, Tseng C, et al. Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy. Biomolecules. 2021;11: pubmed publisher
	Bhandari S, Li R, Simon Santamaria J, McCourt P, Johansen S, Smedsrød B, et al. Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. BMC Mol Cell Biol. 2020;21:85 pubmed publisher
	Taylor S, Whitfield M, Barratt J, Didangelos A. The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix. J Immunol. 2020;205:2243-2254 pubmed publisher
	Kosmac K, Gonzalez Freire M, McDermott M, White S, Walton R, Sufit R, et al. Correlations of Calf Muscle Macrophage Content With Muscle Properties and Walking Performance in Peripheral Artery Disease. J Am Heart Assoc. 2020;9:e015929 pubmed publisher
	Podolsky M, Yang C, Valenzuela C, Datta R, Huang S, Nishimura S, et al. Age-dependent regulation of cell-mediated collagen turnover. JCI Insight. 2020;5: pubmed publisher
	Jensen K, Jacobsen M, Schrøder H, Aagaard P, Nielsen J, Jørgensen A, et al. The immune system in sporadic inclusion body myositis patients is not compromised by blood-flow restricted exercise training. Arthritis Res Ther. 2019;21:293 pubmed publisher
	Cui C, Driscoll R, Piao Y, Chia C, Gorospe M, Ferrucci L. Skewed macrophage polarization in aging skeletal muscle. Aging Cell. 2019;18:e13032 pubmed publisher
	De Vlieger G, Vanhorebeek I, Wouters P, Derese I, Casaer M, Debaveye Y, et al. The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT. Crit Care. 2019;23:270 pubmed publisher
	Liu B, Hutchison A, Thompson C, Lange K, Heilbronn L. Markers of adipose tissue inflammation are transiently elevated during intermittent fasting in women who are overweight or obese. Obes Res Clin Pract. 2019;13:408-415 pubmed publisher
	Nielsen M, Andersen M, Rittig N, Rødgaard Hansen S, Grønbaek H, Moestrup S, et al. The macrophage-related biomarkers sCD163 and sCD206 are released by different shedding mechanisms. J Leukoc Biol. 2019;106:1129-1138 pubmed publisher
	Zhang T, Liu L, Lai W, Zeng Y, Xu H, Lan Q, et al. Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis. Oncol Rep. 2019;41:2790-2802 pubmed publisher
	Yang R, Wu M, Lin S, Nargund R, Li X, Kelly T, et al. A glucose-responsive insulin therapy protects animals against hypoglycemia. JCI Insight. 2018;3: pubmed publisher
	Malada Edelstein Y, Hadad N, Levy R. Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia. J Neuroinflammation. 2017;14:33 pubmed publisher
	Øie C, Snapkov I, Elvevold K, Sveinbjørnsson B, Smedsrød B. FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides. PLoS ONE. 2016;11:e0160602 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2534

SKU :

AF2534

product name :

Human MMR/CD206 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human MMR/CD206 Antibody from R&D Systems is a goat polyclonal antibody to MMR/CD206/Mannose Receptor. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque),rat,transgenic mouse. The Human MMR/CD206 Antibody has been validated for the following applications: Immunohistochemistry,Functional Assay,Bioassay,Flow Cytometry,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.

target :

MMR/CD206

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 3-15 ug/mL, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human MMR/CD206, Leu19-Lys1383 (Thr399Ala) & (Leu407Phe), Accession # P22897

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque),Rat,Transgenic Mouse

specificity :

Detects human MMR/CD206 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse MMR is observed.

gene symbol :

MRC1

top caption :

Detection of Human MMR/CD206 antibody by Western Blot.

accessionNumbers :

P22897

applications :

Simple Western,Bioassay,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Functional Assay,ELISA Capture

USD :

519 USD

alt names :

CD206, CLEC13D, CLEC13Dmacrophage mannose receptor 1, C-type lectin domain family 13 member D, mannose receptor, C type 1, MMRCD206 antigen, MRC1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage